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UniProtKB - D3ZZ25 (D3ZZ25_RAT)
Protein
Submitted name:
Zinc finger protein 280C
Gene
Zfp280c
Organism
Rattus norvegicus (Rat)
Status
Functioni
May function as a transcription factor.
ARBA annotationGO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- regulation of transcription, DNA-templated Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger protein 280CImported |
Gene namesi | |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1564669, Zfp280c |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSRNOG00000006797, Expressed in testis and 20 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 305 – 325 | C2H2-typeInterPro annotationAdd BLAST | 21 | |
Domaini | 342 – 363 | C2H2-typeInterPro annotationAdd BLAST | 22 | |
Domaini | 372 – 393 | C2H2-typeInterPro annotationAdd BLAST | 22 | |
Domaini | 459 – 479 | C2H2-typeInterPro annotationAdd BLAST | 21 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 33 | DisorderedSequence analysisAdd BLAST | 33 | |
Regioni | 52 – 199 | DisorderedSequence analysisAdd BLAST | 148 | |
Regioni | 505 – 594 | DisorderedSequence analysisAdd BLAST | 90 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 16 | Acidic residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 52 – 87 | Polar residuesSequence analysisAdd BLAST | 36 | |
Compositional biasi | 101 – 199 | Polar residuesSequence analysisAdd BLAST | 99 | |
Compositional biasi | 505 – 580 | Polar residuesSequence analysisAdd BLAST | 76 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000162128 |
HOGENOMi | CLU_010097_1_0_1 |
InParanoidi | D3ZZ25 |
OMAi | PKCNIQF |
OrthoDBi | 105829at2759 |
TreeFami | TF331707 |
Family and domain databases
InterProi | View protein in InterPro IPR025243, DUF4195 IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF13836, DUF4195, 1 hit |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 9 hits |
SUPFAMi | SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 4 hits |
i Sequence
Sequence statusi: Complete.
D3ZZ25-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAELIMECEE EELEPWQQKV EESQNKDDDD DDDELIFVGE ISSSKPAISN
60 70 80 90 100
ILNRCSPGSS SKGLKNGSFS PALSNIFKPT NQHYRNPPSH PLIALPSFYP
110 120 130 140 150
APKSSESSDV QTVSKPTFLK TSPQDDSGAS SASLLDSTKD IPSSNVLQKS
160 170 180 190 200
TGVNQTLRLK HPSSSKVNSV NPKKPKTNAS ISETGRGSAS SLNMSPSEAS
210 220 230 240 250
SQVVLSNMNT SSIQSAAGKP SLRSCPKCNV KFSLLDPLKC HMKRCCPDMI
260 270 280 290 300
NKFLETLKSE NSKAVSRAII GSDKEKLIML VSDFYYGRHE GTIEEDQKAP
310 320 330 340 350
TTFKCFSCTK VLKNNIRFMN HMKHHLEFEK QNNETWESHT TCQHCYRQYP
360 370 380 390 400
NPFQLQCHIE STHTPHDFST ICKICELSFE TEHLLLQHMK DTHKPGEMPY
410 420 430 440 450
ICQVCQFRSS IFSDVETHFR SSHENTKNLL CPFCLKVSRM ATPYMNHYMR
460 470 480 490 500
HQKKGIYRCP KCRLQFLTSK EKIDHKLEHR TFIKPKELEG LPPGTKVTIR
510 520 530 540 550
ASLGSIQSRS SSPPSSTIPS TSLQLSVPKS KTTTTKNTTT KNNSKVSANK
560 570 580 590 600
VTTTSPQTMS TTTGKTNASK PGTGTTKSKA KPSNKQKRQR TRKNKFSIDL
610 620 630 640 650
RNLRCHQGTH TCIECHSKIK DFSSHFSTYI NCDFCKYTTN CNKAFTNHMS
660 670 680 690 700
SHNDHPSKQL CIFKKHSRAL RGITLVCLKC DFLADTSGLD RMAKHLNQRK
710 720
THTCQVVIEN VTERTGTSES TSDGLLK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07041619 Genomic DNA No translation available. AABR07041620 Genomic DNA No translation available. AABR07041621 Genomic DNA No translation available. |
RefSeqi | XP_006227598.1, XM_006227536.1 XP_006257604.1, XM_006257542.2 XP_008756778.1, XM_008758556.2 XP_008771764.1, XM_008773542.2 |
Genome annotation databases
Ensembli | ENSRNOT00000044435; ENSRNOP00000051158; ENSRNOG00000006797 |
GeneIDi | 302812 |
UCSCi | RGD:1564669, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07041619 Genomic DNA No translation available. AABR07041620 Genomic DNA No translation available. AABR07041621 Genomic DNA No translation available. |
RefSeqi | XP_006227598.1, XM_006227536.1 XP_006257604.1, XM_006257542.2 XP_008756778.1, XM_008758556.2 XP_008771764.1, XM_008773542.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000051158 |
Proteomic databases
PaxDbi | D3ZZ25 |
PeptideAtlasi | D3ZZ25 |
Genome annotation databases
Ensembli | ENSRNOT00000044435; ENSRNOP00000051158; ENSRNOG00000006797 |
GeneIDi | 302812 |
UCSCi | RGD:1564669, rat |
Organism-specific databases
CTDi | 208968 |
RGDi | 1564669, Zfp280c |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000162128 |
HOGENOMi | CLU_010097_1_0_1 |
InParanoidi | D3ZZ25 |
OMAi | PKCNIQF |
OrthoDBi | 105829at2759 |
TreeFami | TF331707 |
Gene expression databases
Bgeei | ENSRNOG00000006797, Expressed in testis and 20 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR025243, DUF4195 IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF13836, DUF4195, 1 hit |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 9 hits |
SUPFAMi | SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 4 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | D3ZZ25_RAT | |
Accessioni | D3ZZ25Primary (citable) accession number: D3ZZ25 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | July 22, 2015 | |
Last modified: | January 19, 2022 | |
This is version 76 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |