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Protein
Submitted name:

Zinc finger with KRAB and SCAN domains 2

Gene

Zkscan2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

Biological processTranscription, Transcription regulationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger with KRAB and SCAN domains 2Imported
Gene namesi
Name:Zkscan2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1359568 Zkscan2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiD3ZXU0
PRIDEiD3ZXU0

Expressioni

Gene expression databases

BgeeiENSRNOG00000024245 Expressed in 2 organ(s), highest expression level in brain

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000020281

Structurei

3D structure databases

ProteinModelPortaliD3ZXU0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 126SCAN boxInterPro annotationAdd BLAST82
Domaini222 – 293KRABInterPro annotationAdd BLAST72
Domaini768 – 795C2H2-typeInterPro annotationAdd BLAST28
Domaini796 – 823C2H2-typeInterPro annotationAdd BLAST28
Domaini824 – 851C2H2-typeInterPro annotationAdd BLAST28
Domaini852 – 879C2H2-typeInterPro annotationAdd BLAST28
Domaini880 – 907C2H2-typeInterPro annotationAdd BLAST28
Domaini908 – 935C2H2-typeInterPro annotationAdd BLAST28

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00530000063287
InParanoidiD3ZXU0
KOiK09229
OMAiTFRKCFR
OrthoDBiEOG091G02KC
TreeFamiTF336839

Family and domain databases

CDDicd07936 SCAN, 1 hit
Gene3Di1.10.4020.10, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR003309 SCAN_dom
IPR038269 SCAN_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF02023 SCAN, 1 hit
PF00096 zf-C2H2, 6 hits
SMARTiView protein in SMART
SM00431 SCAN, 1 hit
SM00355 ZnF_C2H2, 6 hits
SUPFAMiSSF57667 SSF57667, 4 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS50804 SCAN_BOX, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 6 hits
PS50157 ZINC_FINGER_C2H2_2, 6 hits

Sequencei

Sequence statusi: Complete.

D3ZXU0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATVINPQMD VEVEECLIMK VEKDSGWASE PILERSDSTE CESFRKCFRQ
60 70 80 90 100
FCYEDVTGPH EAFSKLWELC CRWLKPEMRS KEQILEQLVI EQFLTILPEK
110 120 130 140 150
IQAWAQRQCP ESGEEAVALV VHLEKETRRL RKQVSGPQHS EKQAPPRTVW
160 170 180 190 200
EVANYEPEQL ETQHRVVSRE EAGNFHSGHQ EQLNQKREHR PLPKNAHSSV
210 220 230 240 250
WAPVPSSEWT AVDEEATTQE PVRDIHTVRS FPYKRSVQQV PAHRDLYHEI
260 270 280 290 300
RKESACSVVS LGDTVSAPNK IAQLEQKKEP WTVGLHSSNK RTSVLQSKIS
310 320 330 340 350
KEKSVHAVQI PARNAGKVWR EQQQWGLEDE KIAGVHWSYE ETKTFLAILK
360 370 380 390 400
ESRFYETLQA CPRNSQVYGA VAEWLRECGF LRTPEQCRTK FKSLQKSYRK
410 420 430 440 450
VRNGHMLEPC AFFEDMDALL NPEAHTSSTE RPKAVISLPL KRTAVSAKEQ
460 470 480 490 500
VSLVEEEEGA EDSDGDEVGI EFVRKSEIRA APILFQNLSG VHWGYEETKT
510 520 530 540 550
FLDILQETRF YEALQACHRK SKLYGVVAEQ LRECGFLRTP EQCRTKFKSL
560 570 580 590 600
QKSYRKVKNG HVLESCAFYK EMDALVNCRT AALPTNTSEE IPSLSRQERG
610 620 630 640 650
HIEVEPQEPT TWEPEESSQE AVLEDSGSER MSEEEITEEP EFEGSAGLPQ
660 670 680 690 700
SPTDFEIGNI IKEAPTQVIF KDTESHRALI EKPKRFVSQN TNPSKYGKRE
710 720 730 740 750
CFSGRHWENL QGVRQGKLMS QPRDTGKAVV HQRPFVGRRP YRLLKYGENF
760 770 780 790 800
GRSARLVCRM THQKENPYKC GVCGKCFGRS RSLIRHQRIH TGEKPFKCLD
810 820 830 840 850
CGKSFNDSSN FGAHLRIHTG EKPYRCRECG KCFSQSSSLI IHQRTHTGEK
860 870 880 890 900
PYQCEECGKS FTNSSHFSAH RRAHTGENPY KCGDCEKSFN NCTRFREHRR
910 920 930 940 950
IHTGEKPYTC AQCGKHFNKS SFLTKHREIH IREKPLPYSP SVYSPENLLK
960
ARSAELRKTF
Length:960
Mass (Da):110,506
Last modified:April 3, 2013 - v2
Checksum:iA89CD08133F9FE88
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07005667 Genomic DNA No translation available.
RefSeqiXP_001079250.1, XM_001079250.6
XP_006230261.1, XM_006230199.3
UniGeneiRn.162453

Genome annotation databases

EnsembliENSRNOT00000020281; ENSRNOP00000020281; ENSRNOG00000024245
GeneIDi368120
KEGGirno:368120

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07005667 Genomic DNA No translation available.
RefSeqiXP_001079250.1, XM_001079250.6
XP_006230261.1, XM_006230199.3
UniGeneiRn.162453

3D structure databases

ProteinModelPortaliD3ZXU0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000020281

Proteomic databases

PaxDbiD3ZXU0
PRIDEiD3ZXU0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000020281; ENSRNOP00000020281; ENSRNOG00000024245
GeneIDi368120
KEGGirno:368120

Organism-specific databases

CTDi342357
RGDi1359568 Zkscan2

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00530000063287
InParanoidiD3ZXU0
KOiK09229
OMAiTFRKCFR
OrthoDBiEOG091G02KC
TreeFamiTF336839

Gene expression databases

BgeeiENSRNOG00000024245 Expressed in 2 organ(s), highest expression level in brain

Family and domain databases

CDDicd07936 SCAN, 1 hit
Gene3Di1.10.4020.10, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR003309 SCAN_dom
IPR038269 SCAN_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF02023 SCAN, 1 hit
PF00096 zf-C2H2, 6 hits
SMARTiView protein in SMART
SM00431 SCAN, 1 hit
SM00355 ZnF_C2H2, 6 hits
SUPFAMiSSF57667 SSF57667, 4 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS50804 SCAN_BOX, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 6 hits
PS50157 ZINC_FINGER_C2H2_2, 6 hits
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZXU0_RAT
AccessioniPrimary (citable) accession number: D3ZXU0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: November 7, 2018
This is version 68 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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