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Protein
Submitted name:

Leucine rich repeat containing 4C (Predicted), isoform CRA_a

Gene

Lrrc4c

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Leucine rich repeat containing 4C (Predicted), isoform CRA_aImported
Submitted name:
Leucine-rich repeat-containing 4CImported
Gene namesi
Name:Lrrc4cImported
Synonyms:Lrrc4c_predictedImported
ORF Names:rCG_27044Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1311013 Lrrc4c

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei528 – 548HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 44Sequence analysisAdd BLAST44
ChainiPRO_501528789445 – 640Sequence analysisAdd BLAST596

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000029798 Expressed in 8 organ(s), highest expression level in brain

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000044234

Structurei

3D structure databases

SMRiD3ZXT1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini354 – 442Ig-likeInterPro annotationAdd BLAST89

Keywords - Domaini

Leucine-rich repeatSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0619 Eukaryota
COG4886 LUCA
GeneTreeiENSGT00760000118831
KOiK07523
OMAiIMTHGAY
OrthoDBiEOG091G037N
TreeFamiTF324303

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR013106 Ig_V-set
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR026906 LRR_5
IPR032675 LRR_dom_sf
IPR026878 LRRC4C
IPR000372 LRRNT
PANTHERiPTHR24369:SF8 PTHR24369:SF8, 1 hit
PfamiView protein in Pfam
PF07679 I-set, 1 hit
PF13306 LRR_5, 1 hit
PF13855 LRR_8, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00408 IGc2, 1 hit
SM00406 IGv, 1 hit
SM00369 LRR_TYP, 8 hits
SM00013 LRRNT, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS51450 LRR, 7 hits

Sequencei

Sequence statusi: Complete.

D3ZXT1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLNKMTLHPQ QIMIGPRFNR ALFDPLLVVL LALQLLVVAG LVRAQTCPSV
60 70 80 90 100
CSCSNQFSKV ICVRKNLREV PDGISTNTRL LNLHENQIQI IKVNSFKHLR
110 120 130 140 150
HLEILQLSRN HIRTIEIGAF NGLANLNTLE LFDNRLTTIP NGAFVYLSKL
160 170 180 190 200
KELWLRNNPI ESIPSYAFNR IPSLRRLDLG ELKRLSYISE GAFEGLSNLR
210 220 230 240 250
YLNLAMCNLR EIPNLTPLIK LDELDLSGNH LSAIRPGSFQ GLMHLQKLWM
260 270 280 290 300
IQSQIQVIER NAFDNLQSLV EINLAHNNLT LLPHDLFTPL HHLERIHLHH
310 320 330 340 350
NPWNCNCDIL WLSWWIRDMA PSNTACCARC NTPPNLKGRY IGELDQNYFT
360 370 380 390 400
CYAPVIVEPP ADLNVTEGMA AELKCRASTS LTSVSWITPN GTVMTHGAYK
410 420 430 440 450
VRIAVLSDGT LNFTNVTVQD TGMYTCMVSN SVGNTTASAT LNVTAATTTP
460 470 480 490 500
FSYFSTVTVE TMEPSQDEAR TTDNNVGPTP VIDWETTNVT TSLTPQSTRS
510 520 530 540 550
TEKTFTIPVT DINSGIPGID EVMKTTKIII GCFVAITLMA AVMLVIFYKM
560 570 580 590 600
RKQHHRQNHH APTRTVEIIN VDDEITGDTP MESHLPMPAI EHEHLNHYNS
610 620 630 640
YKSPFNHTTT VNTINSIHSS VHEPLLIRMN SKDNVQETQI
Length:640
Mass (Da):71,992
Last modified:April 20, 2010 - v1
Checksum:i9810515A995CAB6B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07052952 Genomic DNA No translation available.
AABR07052953 Genomic DNA No translation available.
AABR07052954 Genomic DNA No translation available.
AABR07052955 Genomic DNA No translation available.
AABR07052956 Genomic DNA No translation available.
AABR07052957 Genomic DNA No translation available.
AABR07052958 Genomic DNA No translation available.
AABR07052959 Genomic DNA No translation available.
AABR07052960 Genomic DNA No translation available.
AABR07052961 Genomic DNA No translation available.
CH473949 Genomic DNA Translation: EDL79615.1
CH473949 Genomic DNA Translation: EDL79616.1
RefSeqiNP_001101223.1, NM_001107753.1
XP_017447211.1, XM_017591722.1
XP_017447212.1, XM_017591723.1
XP_017447213.1, XM_017591724.1
XP_017447214.1, XM_017591725.1
XP_017447215.1, XM_017591726.1
XP_017447216.1, XM_017591727.1
XP_017447217.1, XM_017591728.1
XP_017447218.1, XM_017591729.1
XP_017447219.1, XM_017591730.1
UniGeneiRn.219303

Genome annotation databases

EnsembliENSRNOT00000044595; ENSRNOP00000044234; ENSRNOG00000029798
GeneIDi311236
KEGGirno:311236
UCSCiRGD:1311013 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07052952 Genomic DNA No translation available.
AABR07052953 Genomic DNA No translation available.
AABR07052954 Genomic DNA No translation available.
AABR07052955 Genomic DNA No translation available.
AABR07052956 Genomic DNA No translation available.
AABR07052957 Genomic DNA No translation available.
AABR07052958 Genomic DNA No translation available.
AABR07052959 Genomic DNA No translation available.
AABR07052960 Genomic DNA No translation available.
AABR07052961 Genomic DNA No translation available.
CH473949 Genomic DNA Translation: EDL79615.1
CH473949 Genomic DNA Translation: EDL79616.1
RefSeqiNP_001101223.1, NM_001107753.1
XP_017447211.1, XM_017591722.1
XP_017447212.1, XM_017591723.1
XP_017447213.1, XM_017591724.1
XP_017447214.1, XM_017591725.1
XP_017447215.1, XM_017591726.1
XP_017447216.1, XM_017591727.1
XP_017447217.1, XM_017591728.1
XP_017447218.1, XM_017591729.1
XP_017447219.1, XM_017591730.1
UniGeneiRn.219303

3D structure databases

SMRiD3ZXT1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000044234

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000044595; ENSRNOP00000044234; ENSRNOG00000029798
GeneIDi311236
KEGGirno:311236
UCSCiRGD:1311013 rat

Organism-specific databases

CTDi57689
RGDi1311013 Lrrc4c

Phylogenomic databases

eggNOGiKOG0619 Eukaryota
COG4886 LUCA
GeneTreeiENSGT00760000118831
KOiK07523
OMAiIMTHGAY
OrthoDBiEOG091G037N
TreeFamiTF324303

Gene expression databases

BgeeiENSRNOG00000029798 Expressed in 8 organ(s), highest expression level in brain

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR013106 Ig_V-set
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR026906 LRR_5
IPR032675 LRR_dom_sf
IPR026878 LRRC4C
IPR000372 LRRNT
PANTHERiPTHR24369:SF8 PTHR24369:SF8, 1 hit
PfamiView protein in Pfam
PF07679 I-set, 1 hit
PF13306 LRR_5, 1 hit
PF13855 LRR_8, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00408 IGc2, 1 hit
SM00406 IGv, 1 hit
SM00369 LRR_TYP, 8 hits
SM00013 LRRNT, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS51450 LRR, 7 hits
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZXT1_RAT
AccessioniPrimary (citable) accession number: D3ZXT1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: September 12, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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