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Entry version 96 (10 Feb 2021)
Sequence version 1 (20 Apr 2010)
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Protein
Submitted name:

Nuclear receptor co-repressor 2

Gene

Ncor2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingARBA annotation, ReceptorImported

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-RNO-2173795, Downregulation of SMAD2/3:SMAD4 transcriptional activity
R-RNO-350054, Notch-HLH transcription pathway
R-RNO-383280, Nuclear Receptor transcription pathway
R-RNO-400206, Regulation of lipid metabolism by PPARalpha
R-RNO-9029569, NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
R-RNO-9623433, NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Nuclear receptor co-repressor 2Imported
Submitted name:
Nuclear receptor co-repressor 2 (Predicted), isoform CRA_aImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ncor2Imported
Synonyms:Ncor2_predictedImported
ORF Names:rCG_21882Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Rat genome database

More...
RGDi
1310293, Ncor2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
D3ZXN9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000001004, Expressed in brain and 21 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
D3ZXN9, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000001334

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
D3ZXN9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini427 – 478SANTInterPro annotationAdd BLAST52
Domaini606 – 657SANTInterPro annotationAdd BLAST52

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 25DisorderedSequence analysisAdd BLAST25
Regioni49 – 114DisorderedSequence analysisAdd BLAST66
Regioni143 – 169DisorderedSequence analysisAdd BLAST27
Regioni190 – 220DisorderedSequence analysisAdd BLAST31
Regioni487 – 618DisorderedSequence analysisAdd BLAST132
Regioni665 – 1071DisorderedSequence analysisAdd BLAST407
Regioni1177 – 1199DisorderedSequence analysisAdd BLAST23
Regioni1255 – 1279DisorderedSequence analysisAdd BLAST25
Regioni1346 – 1367DisorderedSequence analysisAdd BLAST22
Regioni1411 – 1444DisorderedSequence analysisAdd BLAST34
Regioni1480 – 1582DisorderedSequence analysisAdd BLAST103
Regioni1735 – 1827DisorderedSequence analysisAdd BLAST93
Regioni1858 – 1879DisorderedSequence analysisAdd BLAST22
Regioni1899 – 1987DisorderedSequence analysisAdd BLAST89
Regioni2002 – 2079DisorderedSequence analysisAdd BLAST78
Regioni2133 – 2226DisorderedSequence analysisAdd BLAST94
Regioni2339 – 2458DisorderedSequence analysisAdd BLAST120

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili299 – 319Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi53 – 77PolarSequence analysisAdd BLAST25
Compositional biasi78 – 113PolyampholyteSequence analysisAdd BLAST36
Compositional biasi190 – 209PolyampholyteSequence analysisAdd BLAST20
Compositional biasi492 – 510PolarSequence analysisAdd BLAST19
Compositional biasi511 – 563PolyampholyteSequence analysisAdd BLAST53
Compositional biasi585 – 607PolarSequence analysisAdd BLAST23
Compositional biasi703 – 717AcidicSequence analysisAdd BLAST15
Compositional biasi736 – 752PolarSequence analysisAdd BLAST17
Compositional biasi772 – 813Pro-richSequence analysisAdd BLAST42
Compositional biasi831 – 883PolyampholyteSequence analysisAdd BLAST53
Compositional biasi902 – 922PolarSequence analysisAdd BLAST21
Compositional biasi989 – 1003Pro-richSequence analysisAdd BLAST15
Compositional biasi1005 – 1019PolarSequence analysisAdd BLAST15
Compositional biasi1046 – 1061Pro-richSequence analysisAdd BLAST16
Compositional biasi1177 – 1196PolarSequence analysisAdd BLAST20
Compositional biasi1526 – 1554PolarSequence analysisAdd BLAST29
Compositional biasi1555 – 1581PolyampholyteSequence analysisAdd BLAST27
Compositional biasi1739 – 1762PolarSequence analysisAdd BLAST24
Compositional biasi1763 – 1782PolyampholyteSequence analysisAdd BLAST20
Compositional biasi1799 – 1827PolarSequence analysisAdd BLAST29
Compositional biasi1927 – 1952PolarSequence analysisAdd BLAST26
Compositional biasi2025 – 2048PolyampholyteSequence analysisAdd BLAST24
Compositional biasi2212 – 2226PolarSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the N-CoR nuclear receptor corepressors family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1878, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159022

Identification of Orthologs from Complete Genome Data

More...
OMAi
EPGRSIH

Database of Orthologous Groups

More...
OrthoDBi
12227at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00167, SANT, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009057, Homeobox-like_sf
IPR031557, N-CoR_GPS2_interact
IPR001005, SANT/Myb
IPR017884, SANT_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15784, GPS2_interact, 1 hit
PF00249, Myb_DNA-binding, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00717, SANT, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689, SSF46689, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51293, SANT, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

D3ZXN9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGSTQPVAQ TWRAAEPRYP PHGISYPVQI ARPHTDVGLL EYQHHPRDYT
60 70 80 90 100
SHLSPGSIIQ PQRRRPSLLS EFQPGSERSQ ELHLRPESRT FLPELGKPDI
110 120 130 140 150
EFTESKRPRL ELLPDTLLRP APLLATGQPS GSEDLTKDRS LAGKLEPVSP
160 170 180 190 200
PSPPHADPEL ELTPSRLSKE ELIQNMDRVD REITMVEQQI SKLKKKQQQL
210 220 230 240 250
EEEAAKPPEP EKPVSPPPIE SKHRSLVQII YDENRKKAEA AHRILEGLGP
260 270 280 290 300
QVELPLYNQP SDTRQYHENI KINQAMRKKL ILYFKRRNHA RKQWEQRFCQ
310 320 330 340 350
RYDQLMEAWE KKVERIENNP RRRAKESKVR EYYEKQFPEI RKQRELQERM
360 370 380 390 400
QSRVGQRGSG LSMSAARSEH EVSEIIDGLS EQENLEKQMR QLAVIPPMLY
410 420 430 440 450
DADQQRIKFI NMNGLMDDPM KVYKDRQVTN MWSEQERDTF REKFMQHPKN
460 470 480 490 500
FGLIASFLER KTVAECVLYY YLTKKNENYK SLVRRSYRRR GKSQQQQQQQ
510 520 530 540 550
QQQQQQQMAR SSQEEKEEKE KEKEADKEEE KQDAENEKEE LSKEKTDDTS
560 570 580 590 600
GEDNDEKEAV ASKGRKTANS QGRRKGRITR SMANEANHEE TATPQQSSEL
610 620 630 640 650
ASMEMNESSR WTEEEMETAK KGLLEHGRNW SAIARMVGSK TVSQCKNFYF
660 670 680 690 700
NYKKRQNLDE ILQQHKLKME KERNARRKKK KTPAAASEET AFPPAAEDEE
710 720 730 740 750
MEASGASANE EELAEEAEAS QASGNEVPRV GECSGPAAVN NSSDTESVPS
760 770 780 790 800
PRTEATKDAG PKPASTEALP AATQPPVPPP EEPATVPDEP CPAPDASGPP
810 820 830 840 850
SPVASPPPAA PPAAVDKDEQ DQAATVPQTE DAKEQKSEAE ELVIDVGKTE
860 870 880 890 900
EPEAPEEPPE SVKSDHKEET EEEPEDKAKG PEAIETVSEA PLKVEEAGSK
910 920 930 940 950
AAVTKGSSSG ATQDSDSSAT CSADEVDEPE GGDKGRLLSP RPSLLTPAGD
960 970 980 990 1000
PRASTSPQKP LDLKQLKQRA AAIPPIVTKV HEPPREDTVP PKPAPPVPPP
1010 1020 1030 1040 1050
TQHLQPEGDV SQQSGGSPRG KCRSPVPPAE KEAEKASFFP AFPAEGPKLP
1060 1070 1080 1090 1100
TEPPRWTSGL PFPIPPREVI KTSPHAADPS AFSYTPPGHP LPLGLHDSAR
1110 1120 1130 1140 1150
PVLPRPPISN PPPLISSAKH PGVLERQLGT ISQQGMSVQL RVPHSEHAKA
1160 1170 1180 1190 1200
PMGPLTMGLP LAVDPKKLGT ALGSTASGSI TKGLPSTRTA DGPSYRGSIT
1210 1220 1230 1240 1250
HGTPADVLYK GTISRIVGED SPSRLDRARE DTLPKGHVIY EGKKGHVLSY
1260 1270 1280 1290 1300
EGGMSVSQCS KEDGRSSSGP PHETAAPKRT YDMMEGRVGR TITSASIEGL
1310 1320 1330 1340 1350
MGRAIPEQHS PHLKEQHHIR GSITQGIPRS YVEAQEDYLR REAKLLKREG
1360 1370 1380 1390 1400
TPPPPPPPRD LTETYKTRPL DPLGPLKLKP THEGVVATVK EAGRSIHEIP
1410 1420 1430 1440 1450
REELRRTPEL PLAPRPLKEG SITQGTPLKY DSGVPSSGSK KHDVRSIIGS
1460 1470 1480 1490 1500
PGRPFPALHP LDIMADARAL ERACYEESLK SRSGTSSGAG GSITRGAPVV
1510 1520 1530 1540 1550
VPELGKPRQS PLAYEDHGAP FTSHLPRGSP VTTREPTPRL QEGSLLSSKA
1560 1570 1580 1590 1600
SQDRKLTSTP REIAKSPHST VPEHHPHPIS PYEHLLRGVT GVDLYRGHIP
1610 1620 1630 1640 1650
LAFDPTSIPR GIPLEAAAAA YYLPRHLAPS PTYPHLYPPY LIRGYPDTAA
1660 1670 1680 1690 1700
LENRQTIIND YITSQQMHHN AASAMAQRAD MLRGLSPRES SLALNYAAGP
1710 1720 1730 1740 1750
RGIIDLSQVP HLPVLVPPTP GTPATAIDRL AYLPTAPPPF SSRHSSSPLS
1760 1770 1780 1790 1800
PGGPTHLAKP TATSSSERER ERERERDKSI LTSTTTVEHA PIWRPGTEQS
1810 1820 1830 1840 1850
SGAGGSSRPA SHTHQHSPIS PRTQDALQQR PSVLHNTSMK GVVTSVEPGT
1860 1870 1880 1890 1900
PTVLRWARST STSSPVRPAA TFPPATHCPL GGTLEGVYPT LMEPVLLPKE
1910 1920 1930 1940 1950
TSRVTRPERP RVDAGHAFLT KPPAREPASS PSKSSEPRSL APPSSSHTAI
1960 1970 1980 1990 2000
ARTPAKSLAP HHASPDLPAP TSASDLHREK TQSKPFSIQE LELRSLGYHS
2010 2020 2030 2040 2050
GAGYSPDGVE PISPVSSPSL THDKGLSKPL EELEKSHLEG ELRHKQPGPM
2060 2070 2080 2090 2100
KLSGEAAHLP HLRPLPESQP SSSPLLQTAP GIKGHQRVVT LAQHISEVIT
2110 2120 2130 2140 2150
QDYTRHHPQQ LSGPLPAPLY SFPGASCPVL DLRRPPSDLY LPPPDHGTPA
2160 2170 2180 2190 2200
RGSPHSEGGK RSPEPSKTVL SSSEDAIEPV SPPEGMTEPG HARSTAYPLL
2210 2220 2230 2240 2250
YRDGEQGEPR MGSKSPGNTS QPPAFFSKLT ESNSAMVKSK KQEINKKLNT
2260 2270 2280 2290 2300
HNRNEPEYNI GQPGTEIFNM PAITGAGLMT CRSQAVQEHA STNMGLEAII
2310 2320 2330 2340 2350
RKALMGKYDQ WEEPPPLGAN AFNPLNASAS LPAAAMPITT ADGRSDHPLT
2360 2370 2380 2390 2400
SPGGGGKAKV SGRPSSRKAK SPAPGLAPGD RPPSVSSVHS EGDCNRRTPL
2410 2420 2430 2440 2450
TNRVWEDRPS SAGSTPFPYN PLIMRLQAGV MASPPPPGLA AGSGPLAGPH
2460 2470
HAWDEEPKPL LCSQYETLSD SE
Length:2,472
Mass (Da):269,996
Last modified:April 20, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9871751C3645229A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JU91A0A0G2JU91_RAT
Nuclear receptor co-repressor 2
Ncor2
2,463Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AABR07036302 Genomic DNA No translation available.
CH473973 Genomic DNA Translation: EDM13562.1

NCBI Reference Sequences

More...
RefSeqi
NP_001101804.1, NM_001108334.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000001334; ENSRNOP00000001334; ENSRNOG00000001004

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
360801

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:360801

UCSC genome browser

More...
UCSCi
RGD:1310293, rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07036302 Genomic DNA No translation available.
CH473973 Genomic DNA Translation: EDM13562.1
RefSeqiNP_001101804.1, NM_001108334.1

3D structure databases

SMRiD3ZXN9
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000001334

Proteomic databases

PRIDEiD3ZXN9

Genome annotation databases

EnsembliENSRNOT00000001334; ENSRNOP00000001334; ENSRNOG00000001004
GeneIDi360801
KEGGirno:360801
UCSCiRGD:1310293, rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9612
RGDi1310293, Ncor2

Phylogenomic databases

eggNOGiKOG1878, Eukaryota
GeneTreeiENSGT00940000159022
OMAiEPGRSIH
OrthoDBi12227at2759

Enzyme and pathway databases

ReactomeiR-RNO-2173795, Downregulation of SMAD2/3:SMAD4 transcriptional activity
R-RNO-350054, Notch-HLH transcription pathway
R-RNO-383280, Nuclear Receptor transcription pathway
R-RNO-400206, Regulation of lipid metabolism by PPARalpha
R-RNO-9029569, NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
R-RNO-9623433, NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis

Gene expression databases

BgeeiENSRNOG00000001004, Expressed in brain and 21 other tissues
ExpressionAtlasiD3ZXN9, baseline and differential

Family and domain databases

CDDicd00167, SANT, 1 hit
InterProiView protein in InterPro
IPR009057, Homeobox-like_sf
IPR031557, N-CoR_GPS2_interact
IPR001005, SANT/Myb
IPR017884, SANT_dom
PfamiView protein in Pfam
PF15784, GPS2_interact, 1 hit
PF00249, Myb_DNA-binding, 1 hit
SMARTiView protein in SMART
SM00717, SANT, 2 hits
SUPFAMiSSF46689, SSF46689, 2 hits
PROSITEiView protein in PROSITE
PS51293, SANT, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD3ZXN9_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D3ZXN9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: February 10, 2021
This is version 96 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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