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UniProtKB - D3ZXB3 (D3ZXB3_RAT)
Protein
Submitted name:
Mesoderm posterior 2 (Predicted)
Gene
Mesp2
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: RGD
- DNA-binding transcription factor activity Source: RGD
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- protein dimerization activity Source: InterPro
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: RGD
- sequence-specific double-stranded DNA binding Source: RGD
GO - Biological processi
- heart morphogenesis Source: GO_Central
- mesodermal cell migration Source: RGD
- mesoderm formation Source: GO_Central
- Notch signaling pathway Source: RGD
- positive regulation of transcription by RNA polymerase II Source: RGD
- regulation of transcription by RNA polymerase II Source: GO_Central
- signal transduction involved in regulation of gene expression Source: RGD
- somite rostral/caudal axis specification Source: RGD
- somitogenesis Source: RGD
Names & Taxonomyi
Protein namesi | Submitted name: Mesoderm posterior 2 (Predicted)ImportedSubmitted name: Mesoderm posterior bHLH transcription factor 2 |
Gene namesi | ORF Names:rCG_24739Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1305959, Mesp2 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000014925, Expressed in stomach and 16 other tissues |
Interactioni
GO - Molecular functioni
- protein dimerization activity Source: InterPro
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000020047 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 81 – 135 | BHLHInterPro annotationAdd BLAST | 55 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 24 – 92 | DisorderedSequence analysisAdd BLAST | 69 | |
Regioni | 155 – 174 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 318 – 349 | DisorderedSequence analysisAdd BLAST | 32 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 24 – 67 | Polar residuesSequence analysisAdd BLAST | 44 | |
Compositional biasi | 320 – 349 | Polar residuesSequence analysisAdd BLAST | 30 |
Phylogenomic databases
eggNOGi | KOG4029, Eukaryota |
GeneTreei | ENSGT00530000063712 |
HOGENOMi | CLU_064749_0_0_1 |
OMAi | PYCPGMQ |
OrthoDBi | 1072866at2759 |
TreeFami | TF325707 |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR040259, Mesogenin/MesP |
PANTHERi | PTHR20937, PTHR20937, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
i Sequence
Sequence statusi: Complete.
D3ZXB3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAQSPQPQSL QGLDHWVFSQ GWGWARHSDS TSPASSSDSS GSCPCYATRP
60 70 80 90 100
PSQSTGPARS ARNTQVAPNA PRRARPAPAG GQRQSASERE KLRMRTLARA
110 120 130 140 150
LQELRRFLPP SVAPAGQSLT KIETLRLAIR YIGHLSALLG LSEDSLRRRR
160 170 180 190 200
RRSADAAFSH RCPQCPDDSS PSQAQMLGPS LGSDISSGLS WGCPPACPGP
210 220 230 240 250
IISPENLGSR ISNVDPWVTP PYCSQIQSPL HQSLERAADT SHWAPPHACP
260 270 280 290 300
GMQISPEPRN KTGHWTASTE PAELTKVYQS LSVSPEPCLA LGSPPLLPRP
310 320 330 340 350
SCQRLQPQPQ WGCWDHSAEA LSSSEDQGSS PALQLPVTSP TPSSGLQFSG
360
CPELWQEDLE GPPLNIFY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473980 Genomic DNA Translation: EDM08598.1 |
RefSeqi | NP_001099743.1, NM_001106273.1 |
Genome annotation databases
Ensembli | ENSRNOT00000020047.6; ENSRNOP00000020047.2; ENSRNOG00000014925.6 |
GeneIDi | 293046 |
KEGGi | rno:293046 |
UCSCi | RGD:1305959, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473980 Genomic DNA Translation: EDM08598.1 |
RefSeqi | NP_001099743.1, NM_001106273.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000020047 |
Genome annotation databases
Ensembli | ENSRNOT00000020047.6; ENSRNOP00000020047.2; ENSRNOG00000014925.6 |
GeneIDi | 293046 |
KEGGi | rno:293046 |
UCSCi | RGD:1305959, rat |
Organism-specific databases
CTDi | 145873 |
RGDi | 1305959, Mesp2 |
Phylogenomic databases
eggNOGi | KOG4029, Eukaryota |
GeneTreei | ENSGT00530000063712 |
HOGENOMi | CLU_064749_0_0_1 |
OMAi | PYCPGMQ |
OrthoDBi | 1072866at2759 |
TreeFami | TF325707 |
Gene expression databases
Bgeei | ENSRNOG00000014925, Expressed in stomach and 16 other tissues |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR040259, Mesogenin/MesP |
PANTHERi | PTHR20937, PTHR20937, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | D3ZXB3_RAT | |
Accessioni | D3ZXB3Primary (citable) accession number: D3ZXB3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 20, 2010 | |
Last modified: | May 25, 2022 | |
This is version 87 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |