Bach2

Functionⁱ

GO - Molecular functionⁱ

DNA-binding transcription factor activity Source: GO_Central
RNA polymerase II distal enhancer sequence-specific DNA binding Source: GO_Central
transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

import into nucleus Source: Ensembl
protein ubiquitination Source: GOC
transcription by RNA polymerase II Source: GO_Central

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-bindingSAAS annotation
Biological process	Transcription, Transcription regulationSAAS annotation

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: BTB domain and CNC homolog 2Imported
Gene namesⁱ	Name:Bach2Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 5

Organism-specific databases

Rat genome database More...RGDⁱ	1562865 Bach2

RGDⁱ

1562865 Bach2

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	D3ZW33

PaxDbⁱ

D3ZW33

PTM databases

iPTMnetⁱ	D3ZW33
PhosphoSitePlusⁱ	D3ZW33

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000006170 Expressed in 9 organ(s), highest expression level in spleen

Bgeeⁱ

ENSRNOG00000006170 Expressed in 9 organ(s), highest expression level in spleen

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000063410

STRINGⁱ

10116.ENSRNOP00000063410

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	D3ZW33
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	37 – 103	BTBInterPro annotationAdd BLAST		67
Domainⁱ	650 – 695	BZIPInterPro annotationAdd BLAST		46

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	670 – 690	Sequence analysisAdd BLAST		21

Sequence similaritiesⁱ

Belongs to the bZIP family.SAAS annotation

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	ENOG410ISV4 Eukaryota ENOG410ZDVB LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00920000148991
InParanoidⁱ	D3ZW33
KEGG Orthology (KO) More...KOⁱ	K09042
OMAⁱ	IKVCPRS
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02EB
PhylomeDBⁱ	D3ZW33
TreeFamⁱ	TF326681

Family and domain databases

InterProⁱ	View protein in InterPro IPR000210 BTB/POZ_dom IPR004827 bZIP IPR004826 bZIP_Maf IPR011333 SKP1/BTB/POZ_sf IPR008917 TF_DNA-bd_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00651 BTB, 1 hit PF03131 bZIP_Maf, 1 hit
SMARTⁱ	View protein in SMART SM00338 BRLZ, 1 hit SM00225 BTB, 1 hit
SUPFAMⁱ	SSF47454 SSF47454, 1 hit SSF54695 SSF54695, 1 hit
PROSITEⁱ	View protein in PROSITE PS50097 BTB, 1 hit PS50217 BZIP, 1 hit PS00036 BZIP_BASIC, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

D3ZW33-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSVDEKPDSP MYVYESTVHC ANILLGLNDQ RKKDILCDVT LIVERKEFRA 
        60         70         80         90        100
HRAVLAACSE YFWQALVGQT KDDLVVSLPE EVTARGFGPL LQFAYTAKLL 
       110        120        130        140        150
LSRENIREVI RCAEFLRMHN LEDSCFSFLQ TQLLNREDGL FVCRKDSACQ 
       160        170        180        190        200
RPQEDHGNSA GEEEEEEETM DSETARMACA TDQMLPDPIS FEATAIPVAE 
       210        220        230        240        250
KEEALLPESE VPTDTKENSE KGALTQYPRY KKYQLACTKN VYSAASHGTS 
       260        270        280        290        300
GFAGTFSEES PGNSLKPGLS VGQIKSEPPN EETEEESITL CLSGDETDIK 
       310        320        330        340        350
DRPGDVEMDR KQPSPAPPPG TPTGATSLDR SRSVSSPSCL RSLFSIAKGV 
       360        370        380        390        400
ESTGLPSTSQ QHFVRSSACP FNKGISQGDL KTDYTPLAGN YGQPHVGQKD 
       410        420        430        440        450
VSNFAMGSPL RGPGPETLCK QEGELDRRSV IFSASTCDQP NTPVHSYSSV 
       460        470        480        490        500
SSLDKDLSEP VPKSLWVGAG QSLPSSQAYS HGGLMADHLP GRIRPNTSCP 
       510        520        530        540        550
VPIKVCPRSP PLETRTRTSS SCSSYSYAED GSGGSPCSLP LCEFSSSPCS 
       560        570        580        590        600
QGARFLATEH QEPGLMGDGM YNQVRPQIKC EQSYGTNSSD ESGSFSEADS 
       610        620        630        640        650
ESCPVQDRGQ EVKLPFPVDQ ITDLPRNDFQ MMIKMHKLTS EQLEFIHDIR 
       660        670        680        690        700
RRSKNRIAAQ RCRKRKLDCI QNLECEIRKL VCEKEKLLSE RNQLKVCMGE 
       710        720        730        740        750
LLDNFSCLSQ EVCRDIQSPE QIQALHRYCP VLIPMDLPGA SVNPPPLGVE 
       760        770        780        790        800
QSLAPSQCAV GGSVPCCLEP GAAPPGLPWV PSNTSENCTS GRRLEGSDPG 
       810        820        830 
TFSERGPPLE ARSQSVTVDF CQEMTEKCTT DEQPRKDYA

Length:839

Mass (Da):91,944

Last modified:April 20, 2010 - v1

Checksum:ⁱ250FBF6C5AC9AEDE

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07047782 Genomic DNA No translation available. AABR07047783 Genomic DNA No translation available. AABR07047784 Genomic DNA No translation available. AABR07047785 Genomic DNA No translation available. AABR07047786 Genomic DNA No translation available. AABR07047787 Genomic DNA No translation available.
NCBI Reference Sequences More...RefSeqⁱ	NP_001129226.1, NM_001135754.1 XP_008761840.1, XM_008763618.2 XP_017448834.1, XM_017593345.1 XP_017448835.1, XM_017593346.1 XP_017448836.1, XM_017593347.1 XP_017448837.1, XM_017593348.1 XP_017448838.1, XM_017593349.1
UniGeneⁱ	Rn.212302

Genome annotation databases

Ensemblⁱ	ENSRNOT00000065882; ENSRNOP00000063410; ENSRNOG00000006170
GeneIDⁱ	313125
KEGGⁱ	rno:313125
UCSC genome browser More...UCSCⁱ	RGD:1562865 rat

Protein	Similar proteins		Species	Score	Length	Source
D3ZW33	Transcription regulator protein BACH2	)	HUMAN		841	UniRef90_Q9BYV9
Uncharacterized protein		MACNE		974
BTB domain and CNC homolog 2		PANTR		973
Uncharacterized protein		CAVPO		885
BTB domain and CNC homolog 2		CANLF		849
+148

Protein	Similar proteins		Species	Score	Length	Source
D3ZW33	Transcription regulator protein BACH2	)	HUMAN		841	UniRef50_Q9BYV9
Transcription regulator protein BACH2		MOUSE		839
Uncharacterized protein		MACNE		974
BTB domain and CNC homolog 2		PANTR		973
Uncharacterized protein		CAVPO		885
+338

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07047782 Genomic DNA No translation available. AABR07047783 Genomic DNA No translation available. AABR07047784 Genomic DNA No translation available. AABR07047785 Genomic DNA No translation available. AABR07047786 Genomic DNA No translation available. AABR07047787 Genomic DNA No translation available.
RefSeqⁱ	NP_001129226.1, NM_001135754.1 XP_008761840.1, XM_008763618.2 XP_017448834.1, XM_017593345.1 XP_017448835.1, XM_017593346.1 XP_017448836.1, XM_017593347.1 XP_017448837.1, XM_017593348.1 XP_017448838.1, XM_017593349.1
UniGeneⁱ	Rn.212302

3D structure databases

ProteinModelPortalⁱ	D3ZW33
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000063410

STRINGⁱ

10116.ENSRNOP00000063410

PTM databases

iPTMnetⁱ	D3ZW33
PhosphoSitePlusⁱ	D3ZW33

Proteomic databases

PaxDbⁱ	D3ZW33

PaxDbⁱ

D3ZW33

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000065882; ENSRNOP00000063410; ENSRNOG00000006170
GeneIDⁱ	313125
KEGGⁱ	rno:313125
UCSCⁱ	RGD:1562865 rat

Organism-specific databases

CTDⁱ	60468
RGDⁱ	1562865 Bach2

Phylogenomic databases

eggNOGⁱ	ENOG410ISV4 Eukaryota ENOG410ZDVB LUCA
GeneTreeⁱ	ENSGT00920000148991
InParanoidⁱ	D3ZW33
KOⁱ	K09042
OMAⁱ	IKVCPRS
OrthoDBⁱ	EOG091G02EB
PhylomeDBⁱ	D3ZW33
TreeFamⁱ	TF326681

Gene expression databases

Bgeeⁱ	ENSRNOG00000006170 Expressed in 9 organ(s), highest expression level in spleen

Bgeeⁱ

ENSRNOG00000006170 Expressed in 9 organ(s), highest expression level in spleen

Family and domain databases

InterProⁱ	View protein in InterPro IPR000210 BTB/POZ_dom IPR004827 bZIP IPR004826 bZIP_Maf IPR011333 SKP1/BTB/POZ_sf IPR008917 TF_DNA-bd_sf
Pfamⁱ	View protein in Pfam PF00651 BTB, 1 hit PF03131 bZIP_Maf, 1 hit
SMARTⁱ	View protein in SMART SM00338 BRLZ, 1 hit SM00225 BTB, 1 hit
SUPFAMⁱ	SSF47454 SSF47454, 1 hit SSF54695 SSF54695, 1 hit
PROSITEⁱ	View protein in PROSITE PS50097 BTB, 1 hit PS50217 BZIP, 1 hit PS00036 BZIP_BASIC, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	D3ZW33_RAT
Accessionⁱ	D3ZW33Primary (citable) accession number: D3ZW33
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 20, 2010
	Last sequence update:	April 20, 2010
	Last modified:	September 12, 2018
	This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - D3ZW33 (D3ZW33_RAT)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

BTB domain and CNC homolog 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Cytosol

Nucleus

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ