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UniProtKB - D3ZVI8 (D3ZVI8_RAT)
Protein
Submitted name:
Kruppel-like factor 13
Gene
Klf13
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: RGD
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: RGD
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: RGD
- sequence-specific double-stranded DNA binding Source: RGD
GO - Biological processi
- negative regulation of cell population proliferation Source: RGD
- negative regulation of erythrocyte differentiation Source: RGD
- positive regulation of transcription by RNA polymerase II Source: RGD
- regulation of transcription by RNA polymerase II Source: RGD
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Kruppel-like factor 13Submitted name: Similar to BTEB3 protein (Predicted), isoform CRA_aImported |
Gene namesi | ORF Names:rCG_24700Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1565099, Klf13 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000015822, Expressed in brain and 21 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 40 – 69 | C2H2-typeInterPro annotationAdd BLAST | 30 | |
Domaini | 70 – 97 | C2H2-typeInterPro annotationAdd BLAST | 28 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 88 – 131 | DisorderedSequence analysisAdd BLAST | 44 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 106 – 131 | Polar residuesSequence analysisAdd BLAST | 26 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000161911 |
HOGENOMi | CLU_002678_42_10_1 |
OMAi | VARPFAC |
OrthoDBi | 1318335at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 2 hits |
SUPFAMi | SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 2 hits PS50157, ZINC_FINGER_C2H2_2, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
D3ZVI8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSGHNSTFPG TPGLPGSLLC LTVGHFIYPC PNREPGERPF ACSWQECNKK
60 70 80 90 100
FARSDELARH YRTHTGEKKF SCPICEKRFM RSDHLTKHAR RHANFHPGML
110 120 130
QRRGGGSRTG SLSDYSRSDA SSPTISPASS P
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A8I5ZJF5 | A0A8I5ZJF5_RAT | Kruppel-like factor 13 | Klf13 | 289 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473980 Genomic DNA Translation: EDM08377.1 |
RefSeqi | NP_001102617.1, NM_001109147.1 |
Genome annotation databases
Ensembli | ENSRNOT00000066380.2; ENSRNOP00000063436.1; ENSRNOG00000015822.6 |
GeneIDi | 499171 |
KEGGi | rno:499171 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473980 Genomic DNA Translation: EDM08377.1 |
RefSeqi | NP_001102617.1, NM_001109147.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000063436 |
Genome annotation databases
Ensembli | ENSRNOT00000066380.2; ENSRNOP00000063436.1; ENSRNOG00000015822.6 |
GeneIDi | 499171 |
KEGGi | rno:499171 |
Organism-specific databases
CTDi | 51621 |
RGDi | 1565099, Klf13 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000161911 |
HOGENOMi | CLU_002678_42_10_1 |
OMAi | VARPFAC |
OrthoDBi | 1318335at2759 |
Gene expression databases
Bgeei | ENSRNOG00000015822, Expressed in brain and 21 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 2 hits |
SUPFAMi | SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 2 hits PS50157, ZINC_FINGER_C2H2_2, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | D3ZVI8_RAT | |
Accessioni | D3ZVI8Primary (citable) accession number: D3ZVI8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 20, 2010 | |
Last modified: | May 25, 2022 | |
This is version 84 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |