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UniProtKB - D3ZV33 (D3ZV33_RAT)

Entry version 76 (26 Feb 2020)
Sequence version 1 (20 Apr 2010)
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Protein
Submitted name:

Pogo transposable element with ZNF domain (Predicted), isoform CRA_a

Gene

Pogz

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Pogo transposable element with ZNF domain (Predicted), isoform CRA_aImported
Submitted name:
Pogo transposable element-derived with ZNF domainImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PogzImported
Synonyms:Pogz_predictedImported
ORF Names:rCG_51791Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Rat genome database

More...RGDi		1309980 Pogz

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSRNOG00000053599 Expressed in skeletal muscle tissue and 9 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		10116.ENSRNOP00000063205

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini438 – 465C2H2-typeInterPro annotationAdd BLAST28
Domaini474 – 502C2H2-typeInterPro annotationAdd BLAST29
Domaini959 – 1029HTH CENPB-typeInterPro annotationAdd BLAST71

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni185 – 239DisorderedSequence analysisAdd BLAST55
Regioni279 – 305DisorderedSequence analysisAdd BLAST27
Regioni356 – 402DisorderedSequence analysisAdd BLAST47
Regioni815 – 838DisorderedSequence analysisAdd BLAST24
Regioni851 – 913DisorderedSequence analysisAdd BLAST63
Regioni1304 – 1357DisorderedSequence analysisAdd BLAST54

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi185 – 233PolarSequence analysisAdd BLAST49
Compositional biasi857 – 871Pro-richSequence analysisAdd BLAST15
Compositional biasi881 – 895PolarSequence analysisAdd BLAST15
Compositional biasi1312 – 1336PolyampholyteSequence analysisAdd BLAST25
Compositional biasi1342 – 1357AcidicSequence analysisAdd BLAST16

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721 Eukaryota
KOG3105 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000160649

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004875 DDE_SF_endonuclease_dom
IPR009057 Homeobox-like_sf
IPR006600 HTH_CenpB_DNA-bd_dom
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03184 DDE_1, 1 hit
PF03221 HTH_Tnp_Tc5, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00674 CENPB, 1 hit
SM00355 ZnF_C2H2, 8 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46689 SSF46689, 1 hit
SSF57667 SSF57667, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51253 HTH_CENPB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 5 hits
PS50157 ZINC_FINGER_C2H2_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

D3ZV33-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADTDLFMEC EEEELEPWQK ISDVIEDSVV EDYNSVDKTT PAGNTLVQQG 
        60         70         80         90        100
GQPLILTQNP TPGLGTMVTQ PVLRPVQVMQ NANHVTSSPV ASQPIFITTQ 
       110        120        130        140        150
GFPVRNVRPV QNAMNQVGIV LNVQQGQTVR PITLVPAPGT QFVKPTVGVP 
       160        170        180        190        200
QVFSQMTPVR PGSTMPVRPT TNTFTTVIPA TLTIRSTVPQ SQSQQTKSTP 
       210        220        230        240        250
STSTTPIATQ PTALGQLAGQ PPGQPNQTSN PKLAPSFPSP PAVSIASFVT 
       260        270        280        290        300
VKRPGVTGEN SNEVAKLVNT LNTIPSLGQS PGPVVVSNNS SAQRTSGPES 
       310        320        330        340        350
SMKVTSSIPV FDLQDGGRKI CPRCNAQFRV TEALRGHMCY CCPEMVEYQK 
       360        370        380        390        400
KGKSLDAEPS VPSAAKPASP EKTAPVTSTP SSTPIPALSP PTKVPEPSES 
       410        420        430        440        450
AGDTVQTKLI MLVDDFYYGR DGGKAAQLTS FPKVATSFRC PHCTKRLKNN 
       460        470        480        490        500
IRFMNHMKHH VELDQQNGEV DGHTICQHCY RQFSTPFQLQ CHLENVHSPY 
       510        520        530        540        550
ESTTKCKICE WAFESEPLFL QHMKDTHKPG EMPYVCQVCQ YRSSLYSEVD 
       560        570        580        590        600
VHFRMIHEDT RHLLCPYCLK VFKNGNAFQQ HYMRHQKRNV YHCNKCRLQF 
       610        620        630        640        650
LFAKDKIEHK LQHHKTFRKP KQLEGLKPGT KVTIRASRGQ PRTVPVSSND 
       660        670        680        690        700
APSGALQEAA PLTSADPLPV FLYPPVQRNV QKRAVRKMSV MGRQTCLECS 
       710        720        730        740        750
FEIPDFPNHF PTYVHCSLCR YSTCCSRAYA NHMINNHVPR KSPKYLALFK 
       760        770        780        790        800
NFVSGIKLAC TSCTFATSVG DAMAKHLVFN PSHRSSNILP RGLSWMSYSR 
       810        820        830        840        850
LGQTPERVLD RSMKNTYLPP PLLPNKAATV KPVGATSAEP QELAGPVLQA 
       860        870        880        890        900
LPSPASTATP PATPTHPQPS ALPPLATEGT ECLNVNEQEE GSPVTQEPEP 
       910        920        930        940        950
ASGAGSGGSG VGKKEQLSVK KLRVVLFALC CNTEQAAEHF RNPQRRIRRW 
       960        970        980        990       1000
LRRFQASQGE NLEGKYLSFE AEEKLAEWVL IQREQQLPVN EETLFQKATK 
      1010       1020       1030       1040       1050
IGRSLEGGFK ISYEWAVRFM LRHHLTPHAR RAVAHTLPKH VAENAGLFIE 
      1060       1070       1080       1090       1100
FVQRQIHNQD LPLSMIVAID EISLFLDTEV LSSDDRKENA LQTVGTGEPW 
      1110       1120       1130       1140       1150
CDVVLAILAD GTVLPTLVFF RGQANRLANV PDSILLEAKD SGYSDDEIME 
      1160       1170       1180       1190       1200
LWSTRVWKKH TACQHSKSML VMDCHRTHLS EEVLALLSAS STLPAVVPAG 
      1210       1220       1230       1240       1250
CSSKIQPLDV CIKRTVKNFL HKKWKEQARE MADAACDSDV LLQLVLVWLG 
      1260       1270       1280       1290       1300
EVLSVIGDSP DLVQRSFLVA SVLPGPDGNV NSPTRNADMQ EELIASLEEQ 
      1310       1320       1330       1340       1350
LKLNGEQSEE HSASAPRPRS SPEETVEPES LHQLFEGESE TESFYGFEEA 

DLDLMEI
Length:1,357
Mass (Da):149,852
Last modified:April 20, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD2F93D465CEC36CD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JY58A0A0G2JY58_RAT
Pogo transposable element-derived w...
Pogz
1,410Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AABR07012474 Genomic DNA No translation available.
AABR07012475 Genomic DNA No translation available.
AABR07072762 Genomic DNA No translation available.
AC130969 Genomic DNA No translation available.
CH474015 Genomic DNA Translation: EDL85769.1

NCBI Reference Sequences

More...RefSeqi		XP_008759519.1, XM_008761297.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSRNOT00000084023; ENSRNOP00000070100; ENSRNOG00000053599

Database of genes from NCBI RefSeq genomes

More...GeneIDi		310658

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07012474 Genomic DNA No translation available.
AABR07012475 Genomic DNA No translation available.
AABR07072762 Genomic DNA No translation available.
AC130969 Genomic DNA No translation available.
CH474015 Genomic DNA Translation: EDL85769.1
RefSeqiXP_008759519.1, XM_008761297.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000063205

Genome annotation databases

EnsembliENSRNOT00000084023; ENSRNOP00000070100; ENSRNOG00000053599
GeneIDi310658

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		23126
RGDi1309980 Pogz

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
KOG3105 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000160649

Gene expression databases

BgeeiENSRNOG00000053599 Expressed in skeletal muscle tissue and 9 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR004875 DDE_SF_endonuclease_dom
IPR009057 Homeobox-like_sf
IPR006600 HTH_CenpB_DNA-bd_dom
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF03184 DDE_1, 1 hit
PF03221 HTH_Tnp_Tc5, 1 hit
SMARTiView protein in SMART
SM00674 CENPB, 1 hit
SM00355 ZnF_C2H2, 8 hits
SUPFAMiSSF46689 SSF46689, 1 hit
SSF57667 SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS51253 HTH_CENPB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 5 hits
PS50157 ZINC_FINGER_C2H2_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD3ZV33_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D3ZV33
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: February 26, 2020
This is version 76 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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