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Entry version 51 (16 Jan 2019)
Sequence version 2 (03 Apr 2013)
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Protein
Submitted name:

Proline-rich 36

Gene

Prr36

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Proline-rich 36Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Prr36Imported
Synonyms:RGD1566084Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Rat genome database

More...
RGDi
1566084 Prr36

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
D3ZUH5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
D3ZUH5

PRoteomics IDEntifications database

More...
PRIDEi
D3ZUH5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000028892 Expressed in 9 organ(s), highest expression level in brain

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
D3ZUH5 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000063265

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
D3ZUH5

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
D3ZUH5

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1036 – 1079DUF4596InterPro annotationAdd BLAST44

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IXR7 Eukaryota
ENOG410YS4A LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154382

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
D3ZUH5

Identification of Orthologs from Complete Genome Data

More...
OMAi
MTTPPMQ

Database of Orthologous Groups

More...
OrthoDBi
675357at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027907 DUF4596

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15363 DUF4596, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

D3ZUH5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDKRDRIKSG AVPRMPASRT PGLLNPRPPS GSARPPPPVT SAALRVLEAN
60 70 80 90 100
GAMGRRPLVE RAPGACKATL PQTSKAALPQ STVHGAPARS AGSGPRSPAN
110 120 130 140 150
RPPASGKGER APMKTAGQGS ISSPGRASSG TARPGPVVQK GLQPPTKEPV
160 170 180 190 200
VRGKTPETPK RNTLSSGTRR VLSADSLGPT SGASSPAITR RPRVPATEVG
210 220 230 240 250
LPQPTPSARQ RPLTTEAPRK PVSSASEHSA TELSPAIRRR SVAGGSQQKP
260 270 280 290 300
VSRSLIPSAT PQLSPARSGV SPRATPRGPA HTSQLKSKGQ QALHPTQTTV
310 320 330 340 350
PRKNRPSVQS LVSASSLVAR TPPGAPSVQV PDDSLPTTLP PSPPATPPLP
360 370 380 390 400
ASLQLLQAHA SSQPMPHSQS GQGSPLPSPL PLQNLPSPPA TPPLLAPPAC
410 420 430 440 450
LGTEEASDSL PPRAGISPSL PPITQSMPNH QAPSASLPQE PLSVTPFSPA
460 470 480 490 500
PLPLAAPPPQ LLPSPPGSPQ NLPTPLVTPS KLPLSTLTAP PSPVNFSGSP
510 520 530 540 550
PLPQATPSNR NTPPLQDPLF LAIPPPVSSS SSTSPPLLVP LSSVATPPLR
560 570 580 590 600
LPPSPTLPTS PASLSTSPPA LASSPQQATP PPLPLSPLST QLSMGSLSPQ
610 620 630 640 650
ASASFSPTHP VQPHALPSPP LRASPITHPL PLSSPSASPP LPALLSPPAS
660 670 680 690 700
PPLEDPLSPP ASPSSPLATP PPEAPPSLGS PTLSPLTTPP PQASPPALPP
710 720 730 740 750
LPASTSSLDT GTCSLQGALL ALPLLQTSPP LTIPSLQTPS SLALPSLQCP
760 770 780 790 800
SSPLATATPP LQIPLVVLPT LQTPPSPLTT LPPGAPPGLT SPVVQPPSPP
810 820 830 840 850
ASPPLQAPRR PPTPGPDVPI SGPRLTLALA PAAPPPPSRS PSSTLSGPDL
860 870 880 890 900
AGHSSSATST PEELRGYDSG PEGCATISPA PDVELAACHP ASWSRSSAPP
910 920 930 940 950
LAVRGTPGVP LPWPPTAGPG SSDGLCTIYE AEGPESVAPT PGSLDVEPEP
960 970 980 990 1000
RPGPGSAKVT AAACAGASSR SPKSTRLGEL PLGALQASVV QHLLSRTLLL
1010 1020 1030 1040 1050
AAAEGAAAGS EGGSGGSGGG GISGGSRAPL SDAELGRWAE LLSPLDESRA
1060 1070
SITSVTSFSP DDVASPQGDW TVVEVETFH
Length:1,079
Mass (Da):108,187
Last modified:April 3, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i95D5DC40531D7ECB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3ZPT0D3ZPT0_RAT
Proline-rich 36
Prr36 RGD1566084
1,050Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AABR07034980 Genomic DNA No translation available.

NCBI Reference Sequences

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RefSeqi
XP_006248850.1, XM_006248788.3
XP_008767240.1, XM_008769018.2
XP_017453960.1, XM_017598471.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000068586; ENSRNOP00000063265; ENSRNOG00000028892

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
501795

UCSC genome browser

More...
UCSCi
RGD:1566084 rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07034980 Genomic DNA No translation available.
RefSeqiXP_006248850.1, XM_006248788.3
XP_008767240.1, XM_008769018.2
XP_017453960.1, XM_017598471.1

3D structure databases

ProteinModelPortaliD3ZUH5
SMRiD3ZUH5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000063265

Proteomic databases

jPOSTiD3ZUH5
PaxDbiD3ZUH5
PRIDEiD3ZUH5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000068586; ENSRNOP00000063265; ENSRNOG00000028892
GeneIDi501795
UCSCiRGD:1566084 rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80164
RGDi1566084 Prr36

Phylogenomic databases

eggNOGiENOG410IXR7 Eukaryota
ENOG410YS4A LUCA
GeneTreeiENSGT00940000154382
InParanoidiD3ZUH5
OMAiMTTPPMQ
OrthoDBi675357at2759

Gene expression databases

BgeeiENSRNOG00000028892 Expressed in 9 organ(s), highest expression level in brain
ExpressionAtlasiD3ZUH5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR027907 DUF4596
PfamiView protein in Pfam
PF15363 DUF4596, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD3ZUH5_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D3ZUH5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: January 16, 2019
This is version 51 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
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