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UniProtKB - D3ZU42 (D3ZU42_RAT)
Protein
Submitted name:
CREB/ATF bZIP transcription factor
Gene
Crebzf
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity Source: InterPro
- identical protein binding Source: RGD
- transcription cis-regulatory region binding Source: GO_Central
GO - Biological processi
- negative regulation of gene expression, epigenetic Source: RGD
- negative regulation of transcription, DNA-templated Source: RGD
- positive regulation of transcription by RNA polymerase II Source: RGD
- regulation of DNA-binding transcription factor activity Source: RGD
- regulation of transcription by RNA polymerase II Source: RGD
- response to virus Source: RGD
Names & Taxonomyi
Protein namesi | Submitted name: CREB/ATF bZIP transcription factorSubmitted name: RCG39766, isoform CRA_bImported |
Gene namesi | Name:CrebzfImported ORF Names:rCG_39766Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1565584, Crebzf |
Subcellular locationi
Mitochondrion
- mitochondrion Source: Ensembl
Nucleus
- nucleoplasm Source: Ensembl
- nucleus Source: RGD
- RNA polymerase II transcription regulator complex Source: RGD
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSRNOG00000018987, Expressed in thymus and 19 other tissues |
Interactioni
GO - Molecular functioni
- identical protein binding Source: RGD
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000025653 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 218 – 265 | BZIPInterPro annotationAdd BLAST | 48 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 91 | DisorderedSequence analysisAdd BLAST | 91 | |
Regioni | 117 – 157 | DisorderedSequence analysisAdd BLAST | 41 | |
Regioni | 177 – 214 | DisorderedSequence analysisAdd BLAST | 38 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 230 – 264 | Sequence analysisAdd BLAST | 35 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 49 – 65 | Basic and acidic residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 197 – 211 | Polar residuesSequence analysisAdd BLAST | 15 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | ENOG502S3I0, Eukaryota |
GeneTreei | ENSGT00390000016589 |
HOGENOMi | CLU_073094_0_0_1 |
OMAi | PEDMDFL |
OrthoDBi | 1294014at2759 |
TreeFami | TF336153 |
Family and domain databases
InterProi | View protein in InterPro IPR004827, bZIP IPR046347, bZIP_sf |
Pfami | View protein in Pfam PF00170, bZIP_1, 1 hit |
SUPFAMi | SSF57959, SSF57959, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
D3ZU42-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRHSLTKLLA ASGRDFPSRR DSQEPPATRA PPPDPTGAAA GTETSRPGSP
60 70 80 90 100
DREQPHGDGG EPEARRGSRG SVAVRAPAPS PLKMEEEEED AIAMVPKEEQ
110 120 130 140 150
EDMDFLSGLE LADLLDPRQP DWHLEPGLSS PGPLSSSGGG SDSGGLLRGD
160 170 180 190 200
DDDETAAAEM QRFSDLLQRL LNGIGGCSSG SDRGGGEKRR RKSPGGGGGT
210 220 230 240 250
NDNNQATTKS PRKAAAAAAR LNRLKKKEYV MGLESRVRGL AAENQELRAE
260 270 280 290 300
NRELGKRVQA LQEESRYLRA VLANETGLAR LLSRLSGVGL RLTTSLFRDS
310 320 330 340 350
PAGDHDYALP VGKQPQELLE EDDAAGGVCL HVDKDKVSVE FCSACARKAS
SSLKIFFFR
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A8I6G6F0 | A0A8I6G6F0_RAT | CREB/ATF bZIP transcription factor | Crebzf rCG_39766 | 355 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473956 Genomic DNA Translation: EDM18543.1 CH473956 Genomic DNA Translation: EDM18544.1 |
RefSeqi | XP_006229750.1, XM_006229688.3 XP_008757868.1, XM_008759646.1 |
Genome annotation databases
Ensembli | ENSRNOT00000025653.6; ENSRNOP00000025653.3; ENSRNOG00000018987.6 |
GeneIDi | 293112 |
UCSCi | RGD:1565584, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473956 Genomic DNA Translation: EDM18543.1 CH473956 Genomic DNA Translation: EDM18544.1 |
RefSeqi | XP_006229750.1, XM_006229688.3 XP_008757868.1, XM_008759646.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000025653 |
Genome annotation databases
Ensembli | ENSRNOT00000025653.6; ENSRNOP00000025653.3; ENSRNOG00000018987.6 |
GeneIDi | 293112 |
UCSCi | RGD:1565584, rat |
Organism-specific databases
CTDi | 58487 |
RGDi | 1565584, Crebzf |
Phylogenomic databases
eggNOGi | ENOG502S3I0, Eukaryota |
GeneTreei | ENSGT00390000016589 |
HOGENOMi | CLU_073094_0_0_1 |
OMAi | PEDMDFL |
OrthoDBi | 1294014at2759 |
TreeFami | TF336153 |
Gene expression databases
Bgeei | ENSRNOG00000018987, Expressed in thymus and 19 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR004827, bZIP IPR046347, bZIP_sf |
Pfami | View protein in Pfam PF00170, bZIP_1, 1 hit |
SUPFAMi | SSF57959, SSF57959, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | D3ZU42_RAT | |
Accessioni | D3ZU42Primary (citable) accession number: D3ZU42 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 20, 2010 | |
Last modified: | May 25, 2022 | |
This is version 85 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |