Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 79 (29 Sep 2021)
Sequence version 2 (22 Jul 2015)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Family with sequence similarity 171, member B

Gene

Fam171b

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Family with sequence similarity 171, member BImported
Submitted name:
Similar to RIKEN cDNA D430039N05 gene (Predicted), isoform CRA_aImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Fam171bImported
Synonyms:RGD1562526_predictedImported
ORF Names:rCG_26509Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Rat genome database

More...
RGDi
1562526, Fam171b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei287 – 311HelicalSequence analysisAdd BLAST25

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
D3ZTG3

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
D3ZTG3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000004783, Expressed in frontal cortex and 21 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
D3ZTG3, RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000006504

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
D3ZTG3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni411 – 440DisorderedSequence analysisAdd BLAST30
Regioni709 – 760DisorderedSequence analysisAdd BLAST52

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi411 – 439Polar residuesSequence analysisAdd BLAST29
Compositional biasi735 – 760Basic and acidic residuesSequence analysisAdd BLAST26

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM171 family.ARBA annotation

Keywords - Domaini

SignalARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QRHY, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183184

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_019729_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
D3ZTG3

Identification of Orthologs from Complete Genome Data

More...
OMAi
KMPMHSH

Database of Orthologous Groups

More...
OrthoDBi
406002at2759

TreeFam database of animal gene trees

More...
TreeFami
TF331338

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018890, Uncharacterised_FAM171

The PANTHER Classification System

More...
PANTHERi
PTHR31626, PTHR31626, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10577, UPF0560, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D3ZTG3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEVAGASFTL VVPVSVFMLK VQVNDIISRQ YLSQAVVEVF VNYTKTNSTV
60 70 80 90 100
TRSNGAVLIK VPYRLGLSLT IIAYKDGYVL TPLPWKTGRM PIYSSVTLSL
110 120 130 140 150
FPQSQANIWL FEDTVLITGK LTDAKSQPSV QFSKASIKLP DNHHISNVTG
160 170 180 190 200
YLTVLQQFLK GDNFLSAIGI TYSTGFENVE LTPHAAICVK IYSGGKELNV
210 220 230 240 250
AGPIHISLPL LHTSNVNVGD RIPAWTFNMK IGAWVHHDWG TVKEHNGHLI
260 270 280 290 300
WTYDAPHLGY WIAAPSPSTL DLGINEDFPN VIGYHTAFLT AILGGTIVII
310 320 330 340 350
IVCLAALLCY CREKYGTPQK RERNITKLEI LKRDQTTSTT HINHISSVKV
360 370 380 390 400
ALKAEDKPQL FNAKTSSYSP QKKETTKTET EERIPMVKTR DNFKIYNEDV
410 420 430 440 450
SFLSVNHNNY SRNPTQSLEP SIGSKQPKHM NNNLSPSLGD AQEEKRYLTG
460 470 480 490 500
NDEVYGRSHL PEQLMHIYSQ PIAILQTSDL FSMPDQLHAA KSATLPRKGQ
510 520 530 540 550
LVYGQLMEPV NRENFTQTLP KMPMHSHTQD PDAREEDIVL EGQQSLPSQT
560 570 580 590 600
SDWSRYSNSL LESVSVPGTL NEAVVMTPFS SELQGISEQT LLELSKGKPS
610 620 630 640 650
PHPRAWFVSL DGKPVAQVRH SFIDLKKGKR TQSNDTSLDS GVDMNEHQLS
660 670 680 690 700
RKLEREKTFI KSMHQPKILY LEDLDLSSSE SGTTVCSPED PALRHILDGG
710 720 730 740 750
GGVIIEHPRE ESPGSKSTVE DFEANVSPTK KRGRPLPLAK RDSKTNIWKK
760
REERPLIPIN
Length:760
Mass (Da):84,822
Last modified:July 22, 2015 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB875E6C08B7ED118
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AABR07052734 Genomic DNA No translation available.
CH473949 Genomic DNA Translation: EDL79296.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000006504; ENSRNOP00000006504; ENSRNOG00000004783

UCSC genome browser

More...
UCSCi
RGD:1562526, rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07052734 Genomic DNA No translation available.
CH473949 Genomic DNA Translation: EDL79296.1

3D structure databases

SMRiD3ZTG3
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000006504

PTM databases

PhosphoSitePlusiD3ZTG3
SwissPalmiD3ZTG3

Genome annotation databases

EnsembliENSRNOT00000006504; ENSRNOP00000006504; ENSRNOG00000004783
UCSCiRGD:1562526, rat

Organism-specific databases

RGDi1562526, Fam171b

Phylogenomic databases

eggNOGiENOG502QRHY, Eukaryota
GeneTreeiENSGT00950000183184
HOGENOMiCLU_019729_0_1_1
InParanoidiD3ZTG3
OMAiKMPMHSH
OrthoDBi406002at2759
TreeFamiTF331338

Gene expression databases

BgeeiENSRNOG00000004783, Expressed in frontal cortex and 21 other tissues
GenevisibleiD3ZTG3, RN

Family and domain databases

InterProiView protein in InterPro
IPR018890, Uncharacterised_FAM171
PANTHERiPTHR31626, PTHR31626, 1 hit
PfamiView protein in Pfam
PF10577, UPF0560, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD3ZTG3_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D3ZTG3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: September 29, 2021
This is version 79 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again