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UniProtKB - D3ZTE9 (D3ZTE9_RAT)
Protein
Submitted name:
PLAG1-like zinc finger 2
Gene
Plagl2
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: RGD
- metal ion binding Source: UniProtKB-KW
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific DNA binding Source: RGD
GO - Biological processi
- chylomicron assembly Source: RGD
- lipid metabolic process Source: RGD
- positive regulation of intrinsic apoptotic signaling pathway Source: RGD
- positive regulation of transcription by RNA polymerase II Source: RGD
- post-embryonic development Source: RGD
- regulation of transcription by RNA polymerase II Source: GO_Central
- transcription, DNA-templated Source: InterPro
Keywordsi
Molecular function | DNA-bindingARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: PLAG1-like zinc finger 2Submitted name: Pleiomorphic adenoma gene-like 2 (Predicted), isoform CRA_aImported |
Gene namesi | ORF Names:rCG_37391Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1307999, Plagl2 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleus Source: RGD
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSRNOG00000010086, Expressed in thymus and 22 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 68 – 97 | C2H2-typeInterPro annotationAdd BLAST | 30 | |
Domaini | 98 – 125 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 127 – 154 | C2H2-typeInterPro annotationAdd BLAST | 28 |
Sequence similaritiesi
Belongs to the krueppel C2H2-type zinc-finger protein family.ARBA annotation
Keywords - Domaini
RepeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000160566 |
HOGENOMi | CLU_1532070_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR027765, PLAG1/PLAGL2 IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR24408:SF20, PTHR24408:SF20, 1 hit |
Pfami | View protein in Pfam PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
D3ZTE9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTTFFTSVPP WIQDAKQEEE VGWKLVPRPR GREAESQVKC QCEISGTPFS
60 70 80 90 100
NGEKLRPHSL PHPEQRPYSC PQLHCGKAFA SKYKLYRHMA THSAQKPHQC
110 120 130 140 150
MYCDKMFHRK DHLRNHLQTH DPNKEALHCS ECGKNYNTKL GYRRHLAMHA
160 170
ASSGDLSCKV CNWVFSKYIM TPSSS
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0G2JZX7 | A0A0G2JZX7_RAT | PLAG1-like zinc finger 2 | Plagl2 Plagl2_predicted, rCG_37391 | 496 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH474050 Genomic DNA Translation: EDL86010.1 |
RefSeqi | NP_001099998.1, NM_001106528.1 |
Genome annotation databases
Ensembli | ENSRNOT00000068592.2; ENSRNOP00000059668.1; ENSRNOG00000010086.8 |
GeneIDi | 296281 |
KEGGi | rno:296281 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH474050 Genomic DNA Translation: EDL86010.1 |
RefSeqi | NP_001099998.1, NM_001106528.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000059668 |
Genome annotation databases
Ensembli | ENSRNOT00000068592.2; ENSRNOP00000059668.1; ENSRNOG00000010086.8 |
GeneIDi | 296281 |
KEGGi | rno:296281 |
Organism-specific databases
CTDi | 5326 |
RGDi | 1307999, Plagl2 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000160566 |
HOGENOMi | CLU_1532070_0_0_1 |
Gene expression databases
Bgeei | ENSRNOG00000010086, Expressed in thymus and 22 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR027765, PLAG1/PLAGL2 IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR24408:SF20, PTHR24408:SF20, 1 hit |
Pfami | View protein in Pfam PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | D3ZTE9_RAT | |
Accessioni | D3ZTE9Primary (citable) accession number: D3ZTE9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 20, 2010 | |
Last modified: | May 25, 2022 | |
This is version 91 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |