Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 60 (16 Jan 2019)
Sequence version 3 (22 Jul 2015)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Unc-79 homolog, NALCN channel complex subunit

Gene

Unc79

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-RNO-2672351 Stimuli-sensing channels

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Unc-79 homolog, NALCN channel complex subunitImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Unc79Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Rat genome database

More...
RGDi
1311117 Unc79

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
D3ZSV8

PRoteomics IDEntifications database

More...
PRIDEi
D3ZSV8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000008728 Expressed in 7 organ(s), highest expression level in brain

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
D3ZSV8 RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000011775

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3685 Eukaryota
KOG4820 Eukaryota
ENOG410XSPU LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011802

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
D3ZSV8

Identification of Orthologs from Complete Genome Data

More...
OMAi
PYRDCEI

Database of Orthologous Groups

More...
OrthoDBi
81334at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR024855 UNC79

The PANTHER Classification System

More...
PANTHERi
PTHR21696 PTHR21696, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D3ZSV8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MISTLATFPP FLHKDIIEYL STSFLPMAIL GSSRREGVPA HVNLSASSML
60 70 80 90 100
MIAMQYTSNP VYHCQLLECL MKYKQEVWKD LLYVIAYGPS QVKPPAVQML
110 120 130 140 150
FHYWPNLKPP GAISEYRGLQ YTAWNPIHCQ HIECHNAINK PAVKMCIDPS
160 170 180 190 200
LSVALGDKPP PLYLCEECSE RISGDHSEWL IDVLLPQAEI SAICQKKNCS
210 220 230 240 250
SHVRRAVVTC FSAGCCGRHG NRPVRYCKRC HSNHHSNEVG ATAETHLYQT
260 270 280 290 300
SPPPINTREC GAEELVCAVE AVISLLKEAE FHAEQREHEL NRRRQLGLSS
310 320 330 340 350
SHHSLDNTDF DNKDDDKHDQ RLLSQFGIWF LVSLCTPSEN TPTESLARLV
360 370 380 390 400
AMVFQWFHST AYMMDDEVGS LVEKLKPQFV TKWLKTVCDV RFDVMVMCLL
410 420 430 440 450
PKPMEFARVG GYWDKSCSTV TQLKEGLNRI LCLIPYNVIS QSVWECIMPE
460 470 480 490 500
WLEAIRTEVP DNQLKEFREV LSKMFDIELC PLPFSMEEMF GFISCRFTGY
510 520 530 540 550
PSTVQEQALL WLHVLSELDI TVPLQLLISM FSDGVNSVKE LANQRKSRAN
560 570 580 590 600
ELAGNLASRR VSVASDPGRR GQHNTLSPFH SPFQSPFRSP MRSPFRSPFK
610 620 630 640 650
NFGHPGGRTI DFDCEDDDMN LNCFILMFDL LLKQMDLQDD GITMGLEHSL
660 670 680 690 700
SKDIISIINN VFQAPWGGSH SCQKDKKATE CSLCQSSILC YQLACELLER
710 720 730 740 750
LAPKEESRLV EPTDSLEDSL LSSRPEFILG PEGEEEENPA AKHGENPGNR
760 770 780 790 800
TVPSEHAAIK NDTERKFCYQ QLPVTLRLIY TIFQEMAKFE EPDILFNMLN
810 820 830 840 850
CLKILCLHGE CLYTARKDHP QFLAYIQDHM LIASLWRVVK SEFSQLSSLA
860 870 880 890 900
VPLLLHALSL PHGADIFWTI INGNFNSKDW KMRFEAVEKV AVICRFLDIH
910 920 930 940 950
SVTKNHLLKY SLAHAFCCFL TAVEDVNPAV ATRAGLLLDT IKRPALQGLC
960 970 980 990 1000
LCLDFQFDTV VKDRPTILSK LLLLHFLKQD IPALSWEFFV NRFETLSLEA
1010 1020 1030 1040 1050
QLHLDCNKEF PFPTTITAVR TNVANLSDAA LWKIKRARFA RNRQKSVRSL
1060 1070 1080 1090 1100
RDSVKGPAES KRALSLPETL TSKIPVRLTR HEQSAPALGG TPEQTPGQQS
1110 1120 1130 1140 1150
PENDNTIKDL LPEDAGIDHQ TVHQLITVLM KFMARDESSA ESDISSAKAF
1160 1170 1180 1190 1200
NTVKRHLYVL LGYDQQEGCF MIAPQKMRLS TCFNAFIAGI AQVMDYNINL
1210 1220 1230 1240 1250
GKHLLPLVVQ VLKYCSCPQL RHYFQQPPRC SLWSLKPHIR QMWLKALLVI
1260 1270 1280 1290 1300
LYKYPYRDCD VSKTLLHLIH ITVNTLNAQY HSCKPHATAG PLYTDNSNIS
1310 1320 1330 1340 1350
RYSEKEKEED SVFDESDIHD TPTGPCNKES QTFFARLKRI GGSRMVKGQP
1360 1370 1380 1390 1400
VGMSVQRSEI ELSEYRETGA LQDSVLHCVR EESIQKKKLR SLKQKSLDIG
1410 1420 1430 1440 1450
NADSLLFTLD EHRRKSCIDR CDIDKPPAQA AYITQRQNDH HGRSRQNSAT
1460 1470 1480 1490 1500
RPDNTEIPKN PGTEGFQETR RPVIPEVRLN CMETFEVRVD SPGKPAPRED
1510 1520 1530 1540 1550
LDLIDLSSDS TSGPEKHSIL STSDSDSLVF EPLPPLRIVE SDEEEMMNQG
1560 1570 1580 1590 1600
NGGPLGNNAA SSPSIPSQPS VLSLSTTPLV QVSVEDCSKD FSSKDSGNHQ
1610 1620 1630 1640 1650
SVSNEDSTVT ALDDLMDSEE LSKSEELREF ISGSPLTLKQ KRDLLQKSFA
1660 1670 1680 1690 1700
VPETSVDYNP EPGQAEEKPT SGAKTVLLKV PEDGENLTES ERPNPSAESD
1710 1720 1730 1740 1750
TEQNPERKVE EDGAEESEFK IQIVPRQRKQ RKIAVSAIQR EYLDISFNIL
1760 1770 1780 1790 1800
DKLGEQKDPD PSAKGLSTLE MPRESSSAPT LEAGAPETSS HSSISTQYRQ
1810 1820 1830 1840 1850
MKRGSLGVLT MSQLMKRQLE HQSSAPHNIS SWDTEQIQPG KGQCNVPMCL
1860 1870 1880 1890 1900
NPDLEGQPLR TRGATKSSLL SAPSIASMFV PAPEEFTEEQ PTVMADKCHD
1910 1920 1930 1940 1950
CGAILEEYDE ETLGLAIVVL STFIHLSPDL AAPLLLDIMQ SVGRLASSTT
1960 1970 1980 1990 2000
FSNQAESMMV PGNAAGVAKQ FLRCIFHQLA PNGIFPQLFQ SAIKDGTFLR
2010 2020 2030 2040 2050
TLATSLMDFN ELSSIAALSQ LLEGLNNKKN LPAGGAMIRC LENIATFMEA
2060 2070 2080 2090 2100
LPMDSPSSLW TTISNQFQTF FAKLPCVLPL KCSLDSSLRI MICLLKIPST
2110 2120 2130 2140 2150
NATRSLLEPF SKLLSFVIQN AVFTLAYLVE LCGLCYRAFT KERDKFYLSR
2160 2170 2180 2190 2200
SVVLELLQAL KLKSPLPDTN LLLLVQFICA DAGTKLAEST ILSKQMIASV
2210 2220 2230 2240 2250
PGCGTAAMEC IRQYVSEVLD FMADMHTLTK LKSHMKTCSQ PLHEDTFGGH
2260 2270 2280 2290 2300
LKVGLAQIAA MEISRGNHRD NKAVIRYLPW LYHPPSAMQQ GPKEFIECVS
2310 2320 2330 2340 2350
HIRLLSWLLL GSLTHNAVCP NASSPCLPIP LDAGSHIADH LIVILIGFPE
2360 2370 2380 2390 2400
QSKTCVLHMC SLFHAFIFAQ LWTVYCEQSA VATNVQNQNE FSFTAILTAL
2410 2420 2430 2440 2450
EFWSRVTPSI LQLMAHNKVM VEMVCLHVIS LMEALQECNS TIFVKLIPMW
2460 2470 2480 2490 2500
LPMIQSNTKY LSAGLQLRLQ AIQNNVNHHS LRTLPGSGQS SAGLAALRKW
2510 2520
LQCTQFKMAQ VEIQSSEAAS QFYPL
Length:2,525
Mass (Da):282,816
Last modified:July 22, 2015 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3854D10D9DFCCDED
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AABR07065414 Genomic DNA No translation available.
AABR07073257 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001258182.1, NM_001271253.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Rn.43444

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000011775; ENSRNOP00000011775; ENSRNOG00000008728

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
314401

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:314401

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07065414 Genomic DNA No translation available.
AABR07073257 Genomic DNA No translation available.
RefSeqiNP_001258182.1, NM_001271253.1
UniGeneiRn.43444

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011775

Proteomic databases

PaxDbiD3ZSV8
PRIDEiD3ZSV8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000011775; ENSRNOP00000011775; ENSRNOG00000008728
GeneIDi314401
KEGGirno:314401

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57578
RGDi1311117 Unc79

Phylogenomic databases

eggNOGiKOG3685 Eukaryota
KOG4820 Eukaryota
ENOG410XSPU LUCA
GeneTreeiENSGT00390000011802
InParanoidiD3ZSV8
OMAiPYRDCEI
OrthoDBi81334at2759

Enzyme and pathway databases

ReactomeiR-RNO-2672351 Stimuli-sensing channels

Gene expression databases

BgeeiENSRNOG00000008728 Expressed in 7 organ(s), highest expression level in brain
GenevisibleiD3ZSV8 RN

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR024855 UNC79
PANTHERiPTHR21696 PTHR21696, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD3ZSV8_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D3ZSV8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: January 16, 2019
This is version 60 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again