Ascl4

Functionⁱ

GO - Molecular functionⁱ

protein dimerization activity Source: InterPro
RNA polymerase II regulatory region sequence-specific DNA binding Source: GO_Central

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

regulation of transcription by RNA polymerase II Source: GO_Central

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Achaete-scute family bHLH transcription factor 4Imported
Gene namesⁱ	Name:Ascl4Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 7

Organism-specific databases

Rat genome database More...RGDⁱ	1307533 Ascl4

RGDⁱ

1307533 Ascl4

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	D3ZS54

PaxDbⁱ

D3ZS54

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000031493 Expressed in 7 organ(s), highest expression level in adult mammalian kidney

Bgeeⁱ

ENSRNOG00000031493 Expressed in 7 organ(s), highest expression level in adult mammalian kidney

Interactionⁱ

GO - Molecular functionⁱ

protein dimerization activity Source: InterPro

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000051020

STRINGⁱ

10116.ENSRNOP00000051020

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	D3ZS54
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	59 – 111	BHLHInterPro annotationAdd BLAST		53

Phylogenomic databases

eggNOGⁱ	KOG4029 Eukaryota ENOG411227D LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063321
InParanoidⁱ	D3ZS54
KEGG Orthology (KO) More...KOⁱ	K09067
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0OGL
PhylomeDBⁱ	D3ZS54
TreeFamⁱ	TF322889

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00083 HLH, 1 hit
Gene3Dⁱ	4.10.280.10, 1 hit
InterProⁱ	View protein in InterPro IPR011598 bHLH_dom IPR036638 HLH_DNA-bd_sf IPR015660 MASH1/Ascl1a-like
PANTHERⁱ	PTHR13935 PTHR13935, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00010 HLH, 1 hit
SMARTⁱ	View protein in SMART SM00353 HLH, 1 hit
SUPFAMⁱ	SSF47459 SSF47459, 1 hit
PROSITEⁱ	View protein in PROSITE PS50888 BHLH, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

D3ZS54-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MEKCKSAGLL ALHSPLRASP LGALARREPC RVSARQDTAD CARRRPCPSL 
        60         70         80         90        100
PPGGVAEPAF LRQRNERERQ RVRCVNEGYA RLRQHLPREL AGQRLSKVET 
       110        120        130        140 
LRAAIGYIKQ LQELLERHRP DLNSDGESKA SSGASPCSSE PEERG

Length:145

Mass (Da):16,090

Last modified:April 20, 2010 - v1

Checksum:ⁱ6AA87B6B29555F53

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC136584 Genomic DNA No translation available.
NCBI Reference Sequences More...RefSeqⁱ	XP_006226038.1, XM_006225976.3 XP_006241232.1, XM_006241170.3

Genome annotation databases

Ensemblⁱ	ENSRNOT00000044252; ENSRNOP00000051020; ENSRNOG00000031493
GeneIDⁱ	299687
KEGGⁱ	rno:299687
UCSC genome browser More...UCSCⁱ	RGD:1307533 rat

Similar proteinsⁱ

50% Identity

Protein	Similar proteins		Species	Score	Length	Source
D3ZS54	Achaete-scute family bHLH transcription factor 4		HORSE		162	UniRef50_F6ZHM0
achaete-scute homolog 4		MESAU		144
Putative achaete-scute-like protein		CRIGR		144
Achaete-scute family bHLH transcription factor 4		MOUSE		144
achaete-scute homolog 4		Enhydra lutris kenyoni		171
+13

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC136584 Genomic DNA No translation available.
RefSeqⁱ	XP_006226038.1, XM_006225976.3 XP_006241232.1, XM_006241170.3

3D structure databases

ProteinModelPortalⁱ	D3ZS54
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000051020

STRINGⁱ

10116.ENSRNOP00000051020

Proteomic databases

PaxDbⁱ	D3ZS54

PaxDbⁱ

D3ZS54

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000044252; ENSRNOP00000051020; ENSRNOG00000031493
GeneIDⁱ	299687
KEGGⁱ	rno:299687
UCSCⁱ	RGD:1307533 rat

Organism-specific databases

CTDⁱ	121549
RGDⁱ	1307533 Ascl4

Phylogenomic databases

eggNOGⁱ	KOG4029 Eukaryota ENOG411227D LUCA
GeneTreeⁱ	ENSGT00530000063321
InParanoidⁱ	D3ZS54
KOⁱ	K09067
OrthoDBⁱ	EOG091G0OGL
PhylomeDBⁱ	D3ZS54
TreeFamⁱ	TF322889

Gene expression databases

Bgeeⁱ	ENSRNOG00000031493 Expressed in 7 organ(s), highest expression level in adult mammalian kidney

Bgeeⁱ

ENSRNOG00000031493 Expressed in 7 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

CDDⁱ	cd00083 HLH, 1 hit
Gene3Dⁱ	4.10.280.10, 1 hit
InterProⁱ	View protein in InterPro IPR011598 bHLH_dom IPR036638 HLH_DNA-bd_sf IPR015660 MASH1/Ascl1a-like
PANTHERⁱ	PTHR13935 PTHR13935, 1 hit
Pfamⁱ	View protein in Pfam PF00010 HLH, 1 hit
SMARTⁱ	View protein in SMART SM00353 HLH, 1 hit
SUPFAMⁱ	SSF47459 SSF47459, 1 hit
PROSITEⁱ	View protein in PROSITE PS50888 BHLH, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	D3ZS54_RAT
Accessionⁱ	D3ZS54Primary (citable) accession number: D3ZS54
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 20, 2010
	Last sequence update:	April 20, 2010
	Last modified:	September 12, 2018
	This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - D3ZS54 (D3ZS54_RAT)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Achaete-scute family bHLH transcription factor 4

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ