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Protein
Submitted name:

Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

Gene

Plod1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDioxygenaseImported, Oxidoreductase
LigandIronSAAS annotation, Metal-bindingSAAS annotation

Enzyme and pathway databases

ReactomeiR-RNO-1650814 Collagen biosynthesis and modifying enzymes

Names & Taxonomyi

Protein namesi
Submitted name:
Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1Imported
Submitted name:
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1Imported
Gene namesi
Name:Plod1Imported
ORF Names:rCG_31468Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi621382 Plod1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_501528779919 – 728Sequence analysisAdd BLAST710

Proteomic databases

PRIDEiD3ZQ74

Expressioni

Gene expression databases

BgeeiENSRNOG00000007763 Expressed in 10 organ(s), highest expression level in heart

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini637 – 728Fe2OG dioxygenaseInterPro annotationAdd BLAST92

Keywords - Domaini

CollagenImported, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1971 Eukaryota
ENOG410Y4QU LUCA
GeneTreeiENSGT00550000074427
KOiK00473
OMAiKFEMGHV
OrthoDBiEOG091G02DK
TreeFamiTF313826

Family and domain databases

InterProiView protein in InterPro
IPR029044 Nucleotide-diphossugar_trans
IPR005123 Oxoglu/Fe-dep_dioxygenase
IPR006620 Pro_4_hyd_alph
IPR001006 Procol_lys_dOase
PfamiView protein in Pfam
PF03171 2OG-FeII_Oxy, 1 hit
SMARTiView protein in SMART
SM00702 P4Hc, 1 hit
SUPFAMiSSF53448 SSF53448, 1 hit
PROSITEiView protein in PROSITE
PS51471 FE2OG_OXY, 1 hit
PS01325 LYS_HYDROXYLASE, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.iShow all

D3ZQ74-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRSLLLLASL AWLLLAQAKD DAKLEDNLLV LTVATKETEG FRRFKRSAQF
60 70 80 90 100
FNYKIQSLGL GEDWSAAGGP SAAGGGQKVR LLKKALKKYA DKEDLVILFV
110 120 130 140 150
DSYDVVFASG PRELLKKFQQ AKSRVVFSAE ELIYPDRRLE AKYPTVPDGK
160 170 180 190 200
RFLGSGGFIG YAPSLSKLVA EWEGQDNDSD QLFYTKIFLD PEKREQINIS
210 220 230 240 250
LDHRCRIFQN LDGALDEVVL KFEMGHVRAR NLAYDTLPVV IHGNGPTKLQ
260 270 280 290 300
VNYLGNYIPR FWTFETGCTV CDEGLRSLKG IGDEALPTVL VGVFIEQPTP
310 320 330 340 350
FLSLFFRRLL HLRYPQKQMR LFIHNQEQHH KLQVEQFLAE HGGEYQSVKL
360 370 380 390 400
VGPEVRMANA DARNMGADLC RQDQTCTYYF SVDADVALTE PNSLRLLIEQ
410 420 430 440 450
NKNVIAPLMT RHGRLWSNFW GALSADGYYA RSEDYVDIVQ GRRVGVWNVP
460 470 480 490 500
YISNIYLIKG SALRAELRHV DLFHYSKLDP DMSFCANVRQ QEVFMFLTNR
510 520 530 540 550
HTFGHLLSLD NYQTTHLHND LWEVFSNPED WKEKYIHENY TKALAGKLVE
560 570 580 590 600
TPCPDVYWFP IFTEVACDEL VEEMEHYGQW SLGDNKDNRI QGGYENVPTI
610 620 630 640 650
DIHMNQITFE REWHKFLVEY IAPLTEKLYP GYYTKAQFDL AFVVRYKPDE
660 670 680 690 700
QPSLMPHHDA STFTINIALN RVGEDYEGGG CRFLRYNCSV RAPRKGWALM
710 720
HPGRLTHYHE GLPTTKGTRY IAVSFVDP
Length:728
Mass (Da):83,613
Last modified:April 3, 2013 - v2
Checksum:iF3219D9FFFF03CB9
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q63321PLOD1_RAT
Procollagen-lysine,2-oxoglutarate 5...
Plod1 Plod
728Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097784 Genomic DNA No translation available.
CH473968 Genomic DNA Translation: EDL81085.1
RefSeqiNP_446279.2, NM_053827.2
UniGeneiRn.4445

Genome annotation databases

EnsembliENSRNOT00000010433; ENSRNOP00000010433; ENSRNOG00000007763
GeneIDi116552
KEGGirno:116552

Similar proteinsi

Entry informationi

Entry nameiD3ZQ74_RAT
AccessioniPrimary (citable) accession number: D3ZQ74
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: September 12, 2018
This is version 72 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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