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UniProtKB - D3ZP58 (D3ZP58_RAT)

Protein
Submitted name:

MGA, MAX dimerization protein

Gene

Mga

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Enzyme and pathway databases

ReactomeiR-RNO-8953750 Transcriptional Regulation by E2F6

Names & Taxonomyi

Protein namesi
Submitted name:
MGA, MAX dimerization proteinImported
Gene namesi
Name:MgaImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1561597 Mga

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiD3ZP58
PRIDEiD3ZP58

PTM databases

iPTMnetiD3ZP58
PhosphoSitePlusiD3ZP58

Expressioni

Gene expression databases

BgeeiENSRNOG00000006378 Expressed in 9 organ(s), highest expression level in spleen
ExpressionAtlasiD3ZP58 baseline and differential

Interactioni

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000060519

Structurei

3D structure databases

ProteinModelPortaliD3ZP58
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2403 – 2454BHLHInterPro annotationAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1128 – 1148Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3585 Eukaryota
ENOG410XSTS LUCA
GeneTreeiENSGT00900000140847
InParanoidiD3ZP58
OMAiMQEAQEF
OrthoDBiEOG091G0I8R
TreeFamiTF106341

Family and domain databases

CDDicd00083 HLH, 1 hit
cd00182 TBOX, 1 hit
Gene3Di2.60.40.820, 1 hit
4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR032060 DUF4801
IPR036638 HLH_DNA-bd_sf
IPR037935 MAX_gene-associated_protein
IPR008967 p53-like_TF_DNA-bd
IPR036960 T-box_sf
IPR001699 TF_T-box
IPR018186 TF_T-box_CS
PANTHERiPTHR11267 PTHR11267, 1 hit
PTHR11267:SF32 PTHR11267:SF32, 1 hit
PfamiView protein in Pfam
PF16059 DUF4801, 1 hit
PF00010 HLH, 1 hit
PF00907 T-box, 1 hit
PRINTSiPR00937 TBOX
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SM00425 TBOX, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
SSF49417 SSF49417, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
PS01264 TBOX_2, 1 hit
PS50252 TBOX_3, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

D3ZP58-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEEKQQIILA NQDGGTVTGA APTFFVILKQ PGNGKTDQGI LVTNRDARAL 
        60         70         80         90        100
LSRESSPGKS KEKICLPADC TVGKITVTLD NNSMWNEFHN RSTEMILTKQ 
       110        120        130        140        150
GRRMFPYCRY WITGLDSNLK YILVMDISPV DSHRYKWNGR WWEPSGKAEP 
       160        170        180        190        200
HILGRVFIHP ESPSTGHYWM HQPVSFYKLK LTNNTLDQEG HIILHSMHRY 
       210        220        230        240        250
LPRLHLVPAE KATEVIQLNG PGVHTFTFPQ TEFFAVTAYQ NIQITQLKID 
       260        270        280        290        300
YNPFAKGFRD DGLSSKPQRD GKQRNSSDQE GNSVSSSPGH RVRLTEGEGS 
       310        320        330        340        350
EIHSGDFDPV LRGHETSSLG LEKAPNNVKQ DFLGFMNTDS THEVPQLKRE 
       360        370        380        390        400
ISESHVSSFE ENSQISSPLN PNGNFNVVIK EEPLDDYDYE LGECPEGITV 
       410        420        430        440        450
KQEETDEETD VYSNSDDDPI LEKQLKRHNK VDNLEADHSS YKWLPNSPGV 
       460        470        480        490        500
AKAKMFKLDA GKMPVVYLEP CAVTKSTVKI SELPDNMLST SRKDKSMLAE 
       510        520        530        540        550
LEYLPAYIEN SDETGFCLSK DSENSLRKHS SDLRMVQKYT LLKEPHWKYP 
       560        570        580        590        600
DIFDSSSTEK THDSSKGSTE DSFSGKEDLG KKRTTMLKMA IPSKTVNASQ 
       610        620        630        640        650
SASPNTPGKR GRPRKLRLSK AGRPPKNTGK SLTASKNIPV GPGNTFPDVK 
       660        670        680        690        700
PDLEDVDGVL FVSFESKEAL DIHAVDGTTE EPSSVQTTTT NDSGSRTRIS 
       710        720        730        740        750
QLEKELIEDL KSLRHKQVIH PALQEVGLKL NSVDPTMSID LKYLGVQLPL 
       760        770        780        790        800
APATSFPLWN VTGTNPASPD AGFPFVSRTG KTNDFTKIKG WRGKFHNASA 
       810        820        830        840        850
SRNEGGNSET SLKNRSAFCS DKLDEYLENE GKLMETSMGF SSNAPTAPTS 
       860        870        880        890        900
PVVYQLPTKS TSYVRTLDSV LKKQSTISPS TSHSVKPHSV TTASRKTKAQ 
       910        920        930        940        950
NKQTTVSGRT KSSYKSILPY PVSPKQKNSH VSPGDKITKN SLSSASDNQV 
       960        970        980        990       1000
TNLVVPSIDE SAFPKQISLR QAQQQHIQQQ GTRPPGLSKS QVKLMDLEDC 
      1010       1020       1030       1040       1050
ALWEGKPRTY ITEERADVSL TTLLTAQASL KTKPIHTIIR KRAPPCNNDF 
      1060       1070       1080       1090       1100
CRLGCVCSSL ALEKRQPAHC RRPDCMFGCT CLKRKVVLVK GGSKTKHLHK 
      1110       1120       1130       1140       1150
KAANRDPLFY DTLGEGGREG GGGVREDEEQ LKEKKKRKKL EYTVCEAEPE 
      1160       1170       1180       1190       1200
QPVRHYPLWV KVDGEVDPEP VYIPTPSVIE PIKPLVLPQP DASSTTIKGK 
      1210       1220       1230       1240       1250
LTPGIKPTRA YTPKPNPVIR EEDKDPVYLY FESMMTCARV RVYERKKDEQ 
      1260       1270       1280       1290       1300
RQLSPPLSPS SSFQQQSSCY SSPENHATKE LDSEQTLKQL ICDLEDDSDK 
      1310       1320       1330       1340       1350
SQEKTWKSSC NEGESSSTSY VHQRSPGGPT KLIEIISDCN WEEDRNKILS 
      1360       1370       1380       1390       1400
ILSQHINSNM PQSLKVGSFI IELASQRKCR GEKTPPVYSS RVKISMPSSQ 
      1410       1420       1430       1440       1450
DQDDMAEKSG SETPDGPLSP GKMDDISPVQ TDALDSVRER LHGGKGLPFY 
      1460       1470       1480       1490       1500
AGLSPSGKLV AYKRKPSSTT SGLIQVASNA KVAASRKPRT LLPSTSNSKM 
      1510       1520       1530       1540       1550
ASSGPTTNRS GKNLKAFVPA KRPIAARPSP GGVFTQFVMS KVGALQQKIP 
      1560       1570       1580       1590       1600
GVRTPQPLTG PQKFSIRPSP VMVVAPVVSS EQVQVCSTVT AAVTTSPQVV 
      1610       1620       1630       1640       1650
LENVTAVPSL TANSDMGAKE ATYSSSASTA GVVEISETNN TTPVTSTQST 
      1660       1670       1680       1690       1700
ATVNLTKTTG ITTSPVASVS FPKPLVASPT ITLPVASTAS TSIVMVTTAA 
      1710       1720       1730       1740       1750
SSSVVTTPTS SLSSVPIILS GINGSPPVSQ RPENAPQIPV TTPQISPNNV 
      1760       1770       1780       1790       1800
KRTGPRLLLI PVQQGSPTLR PIPNPQLQGQ RMVLQPVRSP SGMNLFRHPN 
      1810       1820       1830       1840       1850
GQIVQLLPLH QIRGSNTQPS LQPVVFRNPG SVVGIRLPTP CKSSETPSSS 
      1860       1870       1880       1890       1900
SSSAFSVMSP VIQAVGSSPT VNVISQAPSL LSSGSSFVSQ AGTLTLRISP 
      1910       1920       1930       1940       1950
PETQNLASKT ASESKITPST GGQPVGTASL IPLQSGSFAL LQLPGQKPVP 
      1960       1970       1980       1990       2000
NSVLQHVASL QIKKESQNTD QKDESNSIKR EKETKKALSS KDEVVDPEAN 
      2010       2020       2030       2040       2050
IMKQNSGIIA SEDTFNNSLD DRGDLLDEES LREDTRPYEY SYSTGSHTDE 
      2060       2070       2080       2090       2100
DKDGDEESGN KNENSPKEKQ TVPEVRAGSE NINIMTLQNV RKVRPQKYVE 
      2110       2120       2130       2140       2150
VKVEQQQGSE NPDDFLVLSK EESKFELSGS QVKEQKSNSQ TEAKKDCEDS 
      2160       2170       2180       2190       2200
LGKDSLRERW RKHLKGPLTH KYVGISQDFK KEADVQLFTE MKPCQDNSER 
      2210       2220       2230       2240       2250
DISELLGKSG TIESGGIFKT EDGSWSGISS SAAFSIIPRR ATKGRRGSRR 
      2260       2270       2280       2290       2300
FQGHFLLSKE HMKPKQQANG GRSSADFTVL DLEDEDEEDE NEKTDDSIDE 
      2310       2320       2330       2340       2350
IVDVVSGYQS EEVDVEKNNY VDYIEDDEQV DVETVEELSE EINFTYKKTT 
      2360       2370       2380       2390       2400
AAHTQSFRQQ CHSLISADEK ASEKSRKVSL ISSKLKDDCW SDKPHKETEA 
      2410       2420       2430       2440       2450
FAYYRRTHTA NERRRRGEMR DLFEKLKITL GLLHSSKVSK SLILNRAFSE 
      2460       2470       2480       2490       2500
IQGLTDQADK LIGQKNLLSR KRSILIRKVS SLSGKTEEVV LKKLEYIYAK 
      2510       2520       2530       2540       2550
QQALEAQKRK KKMGSDEFGL SPRISTQLEG SSSSVDLGQM FMSNRRGKPL 
      2560       2570       2580       2590       2600
ILSRRRDQAT ENASPSDTPH SSANLVMTPQ GQLLTLKGPL FSAPVVAVSP 
      2610       2620       2630       2640       2650
ALLEAGLKPQ VASSTMAQSE NDDLFMMPRI VNVTSLAAEE DLGGMSGNKY 
      2660       2670       2680       2690       2700
LHEVPDGKPA LDHLRDVSGN EASSLKDTER ISSRGNHRDS RMALGPTQVF 
      2710       2720       2730       2740       2750
LANKDSGFPH VPDVSTMQAA QEFIPKKMSG DLRGHRHKWK ECELRGERLK 
      2760       2770       2780       2790       2800
SKESQFHKLK MKDLKDSSIE MELRKVASAI EEAALDPSEL LTNMEDEDDT 
      2810       2820       2830       2840       2850
DETLTSLLNE IAFLNQQLND DSGLAELSGS LDTEFPGDAQ QAFISKLAPG 
      2860       2870       2880       2890       2900
NRSAFQVGHL GTGVKELPDV QEESESISPL LLHLEDDDFS ENEKQLGDTA 
      2910       2920       2930       2940       2950
SEPDVLKIVI DSEIKDSLVS HRKSSDGGQS TSGLPAEPES VSSPPILHMK 
      2960       2970       2980       2990       3000
TGPENSSTDT LWRPMPKLAP LGLKVANPPS DADGQSLKVM PALAPIAAKV 
      3010       3020       3030       3040 
GSVGHKMNTT GSDQEGRGSK MMPTLAPVVT KLGNSGVPSS SSGK
Length:3,044
Mass (Da):333,677
Last modified:April 3, 2013 - v2
Checksum:i7EF990750EE5EDE6
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D4A6F9D4A6F9_RAT
MGA, MAX dimerization protein
Mga
2,926Annotation score:
D3ZJB5D3ZJB5_RAT
MGA, MAX dimerization protein
Mga
3,005Annotation score:
D3ZMQ0D3ZMQ0_RAT
MGA, MAX dimerization protein
Mga
2,835Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07053506 Genomic DNA No translation available.
AABR07053507 Genomic DNA No translation available.
RefSeqiXP_006234862.1, XM_006234800.3

Genome annotation databases

EnsembliENSRNOT00000067865; ENSRNOP00000060519; ENSRNOG00000006378
GeneIDi499874

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07053506 Genomic DNA No translation available.
AABR07053507 Genomic DNA No translation available.
RefSeqiXP_006234862.1, XM_006234800.3

3D structure databases

ProteinModelPortaliD3ZP58
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000060519

PTM databases

iPTMnetiD3ZP58
PhosphoSitePlusiD3ZP58

Proteomic databases

PaxDbiD3ZP58
PRIDEiD3ZP58

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000067865; ENSRNOP00000060519; ENSRNOG00000006378
GeneIDi499874

Organism-specific databases

CTDi23269
RGDi1561597 Mga

Phylogenomic databases

eggNOGiKOG3585 Eukaryota
ENOG410XSTS LUCA
GeneTreeiENSGT00900000140847
InParanoidiD3ZP58
OMAiMQEAQEF
OrthoDBiEOG091G0I8R
TreeFamiTF106341

Enzyme and pathway databases

ReactomeiR-RNO-8953750 Transcriptional Regulation by E2F6

Gene expression databases

BgeeiENSRNOG00000006378 Expressed in 9 organ(s), highest expression level in spleen
ExpressionAtlasiD3ZP58 baseline and differential

Family and domain databases

CDDicd00083 HLH, 1 hit
cd00182 TBOX, 1 hit
Gene3Di2.60.40.820, 1 hit
4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR032060 DUF4801
IPR036638 HLH_DNA-bd_sf
IPR037935 MAX_gene-associated_protein
IPR008967 p53-like_TF_DNA-bd
IPR036960 T-box_sf
IPR001699 TF_T-box
IPR018186 TF_T-box_CS
PANTHERiPTHR11267 PTHR11267, 1 hit
PTHR11267:SF32 PTHR11267:SF32, 1 hit
PfamiView protein in Pfam
PF16059 DUF4801, 1 hit
PF00010 HLH, 1 hit
PF00907 T-box, 1 hit
PRINTSiPR00937 TBOX
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SM00425 TBOX, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
SSF49417 SSF49417, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
PS01264 TBOX_2, 1 hit
PS50252 TBOX_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZP58_RAT
AccessioniPrimary (citable) accession number: D3ZP58
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 3, 2013
Last modified: November 7, 2018
This is version 76 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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