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Protein
Submitted name:

Scratch family transcriptional repressor 2

Gene

Scrt2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

  • DNA binding Source: GO_Central
  • DNA-binding transcription factor activity Source: GO_Central

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Scratch family transcriptional repressor 2Imported
Gene namesi
Name:Scrt2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1564796 Scrt2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiD3ZNS5
PRIDEiD3ZNS5

Expressioni

Gene expression databases

BgeeiENSRNOG00000005148 Expressed in 2 organ(s), highest expression level in brain

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000006833

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini155 – 182C2H2-typeInterPro annotationAdd BLAST28
Domaini186 – 213C2H2-typeInterPro annotationAdd BLAST28
Domaini212 – 239C2H2-typeInterPro annotationAdd BLAST28
Domaini240 – 267C2H2-typeInterPro annotationAdd BLAST28
Domaini268 – 298C2H2-typeInterPro annotationAdd BLAST31

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2462 Eukaryota
ENOG41106JS LUCA
GeneTreeiENSGT00390000011027
InParanoidiD3ZNS5
KOiK09219
OMAiLYDGIHS
OrthoDBiEOG091G0Q0V
PhylomeDBiD3ZNS5
TreeFamiTF315515

Family and domain databases

InterProiView protein in InterPro
IPR029794 SCRATCH1/2
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR44270 PTHR44270, 1 hit
PfamiView protein in Pfam
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 5 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 4 hits
PS50157 ZINC_FINGER_C2H2_2, 5 hits

Sequencei

Sequence statusi: Complete.

D3ZNS5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPRSFLVKKI KADGFQCSGV PAPTYHPLET AYVLPGTRGP PGDNGYVAHC
60 70 80 90 100
MPPSGYDGEQ KPGLELAPTE PAYPAAASEE YSDPESPQSS LSARYFRGEA
110 120 130 140 150
AVTDSYSMDA FFISDGRSRR RRAGAGGDAA GAGDGGGGGE RAGRSGATAG
160 170 180 190 200
GGHRHACAEC GKTYATSSNL SRHKQTHRSL DSQLARKCPT CGKAYVSMPA
210 220 230 240 250
LAMHVLTHNL RHKCGVCGKA FSRPWLLQGH MRSHTGEKPF GCAHCGKAFA
260 270 280 290 300
DRSNLRAHMQ THSAFKHYRC RQCDKSFALK SYLHKHCEAA CVKAAEPPPS

AGPAS
Length:305
Mass (Da):32,423
Last modified:April 20, 2010 - v1
Checksum:i91FD03054EDCCFE5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07054319 Genomic DNA No translation available.
RefSeqiNP_001178834.1, NM_001191905.1
UniGeneiRn.228224

Genome annotation databases

EnsembliENSRNOT00000006833; ENSRNOP00000006833; ENSRNOG00000005148
GeneIDi366229
KEGGirno:366229
UCSCiRGD:1564796 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07054319 Genomic DNA No translation available.
RefSeqiNP_001178834.1, NM_001191905.1
UniGeneiRn.228224

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000006833

Proteomic databases

PaxDbiD3ZNS5
PRIDEiD3ZNS5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000006833; ENSRNOP00000006833; ENSRNOG00000005148
GeneIDi366229
KEGGirno:366229
UCSCiRGD:1564796 rat

Organism-specific databases

CTDi85508
RGDi1564796 Scrt2

Phylogenomic databases

eggNOGiKOG2462 Eukaryota
ENOG41106JS LUCA
GeneTreeiENSGT00390000011027
InParanoidiD3ZNS5
KOiK09219
OMAiLYDGIHS
OrthoDBiEOG091G0Q0V
PhylomeDBiD3ZNS5
TreeFamiTF315515

Gene expression databases

BgeeiENSRNOG00000005148 Expressed in 2 organ(s), highest expression level in brain

Family and domain databases

InterProiView protein in InterPro
IPR029794 SCRATCH1/2
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR44270 PTHR44270, 1 hit
PfamiView protein in Pfam
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 5 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 4 hits
PS50157 ZINC_FINGER_C2H2_2, 5 hits
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZNS5_RAT
AccessioniPrimary (citable) accession number: D3ZNS5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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