Nhlh1

Functionⁱ

GO - Molecular functionⁱ

protein dimerization activity Source: InterPro
RNA polymerase II regulatory region sequence-specific DNA binding Source: GO_Central
RNA polymerase II transcription factor activity, sequence-specific DNA binding Source: GO_Central
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: Ensembl

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Nescient helix loop helix 1Imported Submitted name: Nescient helix loop helix 1 (Predicted), isoform CRA_aImported
Gene namesⁱ	Name:Nhlh1Imported Synonyms:Nhlh1_predictedImported ORF Names:rCG_20238Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 13

Organism-specific databases

Rat genome database More...RGDⁱ	1310261 Nhlh1

RGDⁱ

1310261 Nhlh1

Subcellular locationⁱ

GO - Cellular component

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000005166 Expressed in 1 organ(s), highest expression level in Ammon's horn

Bgeeⁱ

ENSRNOG00000005166 Expressed in 1 organ(s), highest expression level in Ammon's horn

Interactionⁱ

GO - Molecular functionⁱ

protein dimerization activity Source: InterPro

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000006862

STRINGⁱ

10116.ENSRNOP00000006862

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	75 – 127	BHLHInterPro annotationAdd BLAST		53

Phylogenomic databases

eggNOGⁱ	KOG4029 Eukaryota ENOG411227D LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119097
KEGG Orthology (KO) More...KOⁱ	K09075
OMAⁱ	MMLNSDA

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00083 HLH, 1 hit
Gene3Dⁱ	4.10.280.10, 1 hit
InterProⁱ	View protein in InterPro IPR011598 bHLH_dom IPR036638 HLH_DNA-bd_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00010 HLH, 1 hit
SMARTⁱ	View protein in SMART SM00353 HLH, 1 hit
SUPFAMⁱ	SSF47459 SSF47459, 1 hit
PROSITEⁱ	View protein in PROSITE PS50888 BHLH, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

D3ZN93-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MMLNSDTMEL DLPPTHSETE SGFSDCGGGP GPDGAGSGDP GVGQVRSLEL 
        60         70         80         90        100
GESGRKDLQH LSREERRRRR RATAKYRTAH ATRERIRVEA FNLAFAELRK 
       110        120        130 
LLPTLPPDKK LSKIEILRLA ICYISYLNHV LDV

Length:133

Mass (Da):14,814

Last modified:April 20, 2010 - v1

Checksum:ⁱF98B1F6177EBD6AB

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07021769 Genomic DNA No translation available. CH473985 Genomic DNA Translation: EDL94673.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001099440.1, NM_001105970.1 XP_006250342.1, XM_006250280.2
UniGeneⁱ	Rn.203557

Genome annotation databases

Ensemblⁱ	ENSRNOT00000006862; ENSRNOP00000006862; ENSRNOG00000005166
GeneIDⁱ	289230
KEGGⁱ	rno:289230
UCSC genome browser More...UCSCⁱ	RGD:1310261 rat

Protein	Similar proteins		Species	Score	Length	Source
D3ZN93	Helix-loop-helix protein 1		HUMAN		133	UniRef90_Q02575
NHLH1 isoform 1		PANTR		133
Nescient helix-loop-helix 1		SAIBB		133
Uncharacterized protein		Cebus capucinus imitator		133
Uncharacterized protein		OTOGA		133
+78

Protein	Similar proteins		Species	Score	Length	Source
D3ZN93	Helix-loop-helix protein 2		HUMAN		135	UniRef50_Q02577
NHLH2 isoform 1		PANTR		135
NHLH2 isoform 1		PONAB		135
Uncharacterized protein		PROCO		135
Uncharacterized protein		MACMU		135
+196

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07021769 Genomic DNA No translation available. CH473985 Genomic DNA Translation: EDL94673.1
RefSeqⁱ	NP_001099440.1, NM_001105970.1 XP_006250342.1, XM_006250280.2
UniGeneⁱ	Rn.203557

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000006862

STRINGⁱ

10116.ENSRNOP00000006862

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000006862; ENSRNOP00000006862; ENSRNOG00000005166
GeneIDⁱ	289230
KEGGⁱ	rno:289230
UCSCⁱ	RGD:1310261 rat

Organism-specific databases

CTDⁱ	4807
RGDⁱ	1310261 Nhlh1

Phylogenomic databases

eggNOGⁱ	KOG4029 Eukaryota ENOG411227D LUCA
GeneTreeⁱ	ENSGT00760000119097
KOⁱ	K09075
OMAⁱ	MMLNSDA

Gene expression databases

Bgeeⁱ	ENSRNOG00000005166 Expressed in 1 organ(s), highest expression level in Ammon's horn

Bgeeⁱ

ENSRNOG00000005166 Expressed in 1 organ(s), highest expression level in Ammon's horn

Family and domain databases

CDDⁱ	cd00083 HLH, 1 hit
Gene3Dⁱ	4.10.280.10, 1 hit
InterProⁱ	View protein in InterPro IPR011598 bHLH_dom IPR036638 HLH_DNA-bd_sf
Pfamⁱ	View protein in Pfam PF00010 HLH, 1 hit
SMARTⁱ	View protein in SMART SM00353 HLH, 1 hit
SUPFAMⁱ	SSF47459 SSF47459, 1 hit
PROSITEⁱ	View protein in PROSITE PS50888 BHLH, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	D3ZN93_RAT
Accessionⁱ	D3ZN93Primary (citable) accession number: D3ZN93
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 20, 2010
	Last sequence update:	April 20, 2010
	Last modified:	September 12, 2018
	This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - D3ZN93 (D3ZN93_RAT)

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Nescient helix loop helix 1

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Organism-specific databases

Subcellular locationⁱ

Nucleus

Expressionⁱ

Gene expression databases

Interactionⁱ

GO - Molecular functionⁱ

Protein-protein interaction databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - D3ZN93 (D3ZN93_RAT)

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Nescient helix loop helix 1

Nhlh1

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ