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UniProtKB - D3ZN93 (D3ZN93_RAT)
Protein
Submitted name:
Nescient helix loop helix 1
Gene
Nhlh1
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: RGD
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- protein dimerization activity Source: InterPro
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: RGD
- sequence-specific double-stranded DNA binding Source: RGD
GO - Biological processi
- positive regulation of transcription by RNA polymerase II Source: RGD
- regulation of transcription by RNA polymerase II Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Nescient helix loop helix 1Submitted name: Nescient helix loop helix 1 (Predicted), isoform CRA_aImported |
Gene namesi | ORF Names:rCG_20238Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1310261, Nhlh1 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000005166, Expressed in brain and 4 other tissues |
Interactioni
GO - Molecular functioni
- protein dimerization activity Source: InterPro
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000006862 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 75 – 127 | BHLHInterPro annotationAdd BLAST | 53 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 79 | DisorderedSequence analysisAdd BLAST | 79 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 22 | Polar residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 50 – 64 | Basic and acidic residuesSequence analysisAdd BLAST | 15 |
Phylogenomic databases
eggNOGi | KOG4029, Eukaryota |
GeneTreei | ENSGT00940000162622 |
HOGENOMi | CLU_148882_1_0_1 |
OMAi | MLNSDQT |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR040238, TAL-like |
PANTHERi | PTHR13864, PTHR13864, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
i Sequence
Sequence statusi: Complete.
D3ZN93-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMLNSDTMEL DLPPTHSETE SGFSDCGGGP GPDGAGSGDP GVGQVRSLEL
60 70 80 90 100
GESGRKDLQH LSREERRRRR RATAKYRTAH ATRERIRVEA FNLAFAELRK
110 120 130
LLPTLPPDKK LSKIEILRLA ICYISYLNHV LDV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473985 Genomic DNA Translation: EDL94673.1 |
RefSeqi | NP_001099440.1, NM_001105970.1 XP_006250342.1, XM_006250280.2 |
Genome annotation databases
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473985 Genomic DNA Translation: EDL94673.1 |
RefSeqi | NP_001099440.1, NM_001105970.1 XP_006250342.1, XM_006250280.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000006862 |
Genome annotation databases
Organism-specific databases
CTDi | 4807 |
RGDi | 1310261, Nhlh1 |
Phylogenomic databases
eggNOGi | KOG4029, Eukaryota |
GeneTreei | ENSGT00940000162622 |
HOGENOMi | CLU_148882_1_0_1 |
OMAi | MLNSDQT |
Gene expression databases
Bgeei | ENSRNOG00000005166, Expressed in brain and 4 other tissues |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR040238, TAL-like |
PANTHERi | PTHR13864, PTHR13864, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | D3ZN93_RAT | |
Accessioni | D3ZN93Primary (citable) accession number: D3ZN93 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 20, 2010 | |
Last modified: | May 25, 2022 | |
This is version 91 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |