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Protein
Submitted name:

SIM bHLH transcription factor 1

Gene

Sim1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
SIM bHLH transcription factor 1Imported
Submitted name:
Single-minded 1 (Predicted)Imported
Gene namesi
Name:Sim1Imported
Synonyms:Sim1_predictedImported
ORF Names:rCG_58489Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 20

Organism-specific databases

RGDi1309949 Sim1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiD3ZMU8

Expressioni

Gene expression databases

BgeeiENSRNOG00000037600 Expressed in 3 organ(s), highest expression level in adult mammalian kidney

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000053843

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 53BHLHInterPro annotationAdd BLAST53
Domaini77 – 140PASInterPro annotationAdd BLAST64
Domaini233 – 270PASInterPro annotationAdd BLAST38
Domaini336 – 765Single-minded C-terminalInterPro annotationAdd BLAST430

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG3559 Eukaryota
ENOG410XY57 LUCA
GeneTreeiENSGT00760000118788
KOiK09100
OMAiERPGSQH
OrthoDBiEOG091G06FQ
TreeFamiTF317772

Family and domain databases

CDDicd00083 HLH, 1 hit
cd00130 PAS, 2 hits
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR001610 PAC
IPR000014 PAS
IPR035965 PAS-like_dom_sf
IPR013767 PAS_fold
IPR013655 PAS_fold_3
IPR010578 SIM_C
PfamiView protein in Pfam
PF00010 HLH, 1 hit
PF00989 PAS, 1 hit
PF08447 PAS_3, 1 hit
PF06621 SIM_C, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SM00086 PAC, 1 hit
SM00091 PAS, 2 hits
SUPFAMiSSF47459 SSF47459, 1 hit
SSF55785 SSF55785, 2 hits
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
PS50112 PAS, 2 hits
PS51302 SIM_C, 1 hit

Sequencei

Sequence statusi: Complete.

D3ZMU8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKEKSKNAAR TRREKENSEF YELAKLLPLP SAITSQLDKA SIIRLTTSYL
60 70 80 90 100
KMRVVFPEGL GEAWGHTSRT SPLDNVGREL GSHLLQTLDG FIFVVAPDGK
110 120 130 140 150
IMYISETASV HLGLSQVELT GNSIYEYIHP ADHDEMTAVL TAHQPYHSHF
160 170 180 190 200
VQEYEIERSF FLRMKCVLAK RNAGLTCGGY KVIHCSGYLK IRQYSLDMSP
210 220 230 240 250
FDGCYQNVGL VAVGHSLPPS AVTEIKLHSN MFMFRASLDM KLIFLDSRVA
260 270 280 290 300
ELTGYEPQDL IEKTLYHHVH GCDTFHLRCA HHLLLVKGQV TTKYYRFLAK
310 320 330 340 350
HGGWVWVQSY ATIVHNSRSS RPHCIVSVNY VLTDTEYKGL QLSLDQISPS
360 370 380 390 400
KPTFSYTSSS TPTITDNRKG AKSRLSSSKS KSRTSPYPQY SGFHTERSES
410 420 430 440 450
DHDSQWGGSP LTDTASPQLL DPERPGSQHE LSCAYRQFPD RGSLCYGFAL
460 470 480 490 500
DHSRLVEDRH FHTQACEGGR CEAGRYFLGA PPAGRDPWWG SRAALPLTKA
510 520 530 540 550
SPESRETYEN SMPHITSVHR LHGRGHWDED SVVSSPDPGS ASESGDRYRS
560 570 580 590 600
EQYQNSPHEP SKIETLIRAT QQMIKEEENR LQLRKAPPDQ LASINGAGKK
610 620 630 640 650
HSLCFANYQQ PPPAGEVCHS SALTSTSPCD HIQQREGKML SPHENDYDNS
660 670 680 690 700
PTALSRISSP SSDRITKSSL ILAKDYLHSD MSPHQTAGDH PAISPNCFGS
710 720 730 740 750
HRQYFDKHAY TLTGYALEHL YDSETIRNYS LGCNGSHFDV TSHLRMQPDP
760
AQGHKGTSVI ITNGS
Length:765
Mass (Da):85,532
Last modified:April 20, 2010 - v1
Checksum:iF49BC0AA9EE52F80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07045656 Genomic DNA No translation available.
AABR07045657 Genomic DNA No translation available.
AABR07045658 Genomic DNA No translation available.
CH474025 Genomic DNA Translation: EDL99652.1
RefSeqiNP_001101111.1, NM_001107641.1
XP_006256666.1, XM_006256604.2
XP_008771216.1, XM_008772994.2
XP_008771217.1, XM_008772995.2
XP_008771218.1, XM_008772996.1
UniGeneiRn.165946

Genome annotation databases

EnsembliENSRNOT00000057010; ENSRNOP00000053843; ENSRNOG00000037600
GeneIDi309888
KEGGirno:309888
UCSCiRGD:1309949 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07045656 Genomic DNA No translation available.
AABR07045657 Genomic DNA No translation available.
AABR07045658 Genomic DNA No translation available.
CH474025 Genomic DNA Translation: EDL99652.1
RefSeqiNP_001101111.1, NM_001107641.1
XP_006256666.1, XM_006256604.2
XP_008771216.1, XM_008772994.2
XP_008771217.1, XM_008772995.2
XP_008771218.1, XM_008772996.1
UniGeneiRn.165946

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000053843

Proteomic databases

PRIDEiD3ZMU8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000057010; ENSRNOP00000053843; ENSRNOG00000037600
GeneIDi309888
KEGGirno:309888
UCSCiRGD:1309949 rat

Organism-specific databases

CTDi6492
RGDi1309949 Sim1

Phylogenomic databases

eggNOGiKOG3559 Eukaryota
ENOG410XY57 LUCA
GeneTreeiENSGT00760000118788
KOiK09100
OMAiERPGSQH
OrthoDBiEOG091G06FQ
TreeFamiTF317772

Gene expression databases

BgeeiENSRNOG00000037600 Expressed in 3 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

CDDicd00083 HLH, 1 hit
cd00130 PAS, 2 hits
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR001610 PAC
IPR000014 PAS
IPR035965 PAS-like_dom_sf
IPR013767 PAS_fold
IPR013655 PAS_fold_3
IPR010578 SIM_C
PfamiView protein in Pfam
PF00010 HLH, 1 hit
PF00989 PAS, 1 hit
PF08447 PAS_3, 1 hit
PF06621 SIM_C, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SM00086 PAC, 1 hit
SM00091 PAS, 2 hits
SUPFAMiSSF47459 SSF47459, 1 hit
SSF55785 SSF55785, 2 hits
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
PS50112 PAS, 2 hits
PS51302 SIM_C, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZMU8_RAT
AccessioniPrimary (citable) accession number: D3ZMU8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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