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Protein

Gamma-tubulin complex component

Gene

Tubgcp3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.UniRule annotation

GO - Molecular functioni

  • gamma-tubulin binding Source: GO_Central
  • structural constituent of cytoskeleton Source: GO_Central

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-380270 Recruitment of mitotic centrosome proteins and complexes
R-RNO-380320 Recruitment of NuMA to mitotic centrosomes

Names & Taxonomyi

Protein namesi
Recommended name:
Gamma-tubulin complex componentUniRule annotation
Gene namesi
Name:Tubgcp3Imported
ORF Names:rCG_43222Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 16

Organism-specific databases

RGDi1305726 Tubgcp3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation, MicrotubuleUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiD3ZMR7

Expressioni

Gene expression databases

BgeeiENSRNOG00000017085 Expressed in 9 organ(s), highest expression level in spleen
ExpressionAtlasiD3ZMR7 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000060338

Family & Domainsi

Sequence similaritiesi

Belongs to the TUBGCP family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2000 Eukaryota
ENOG410XQ5B LUCA
GeneTreeiENSGT00850000132278
KOiK16570

Family and domain databases

InterProiView protein in InterPro
IPR007259 GCP
PANTHERiPTHR19302 PTHR19302, 1 hit
PfamiView protein in Pfam
PF04130 Spc97_Spc98, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

D3ZMR7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATPDQKSPN VLLQNLCCRI LGRSEADVAQ QFQFAVRVIG SNFAPTVERD
60 70 80 90 100
EFLVAEKIKK ELIRQRREAD AALFSELHRK LHSQGVLKNK WSILYLLLNL
110 120 130 140 150
SEDPRKQASK VTSYASLFAQ ALPRDAHSTP YYCARPQTLP LNYQDRSTQS
160 170 180 190 200
SGSLGSSGIS SIGMCGLSGP TPVQPFLPGQ SHQAPGVGDG LRQQLGPRLA
210 220 230 240 250
WTLTGNQPSQ TPTSKAFPNA LSRNLTRSRR EGDPGGTSEV TEAALVRDIL
260 270 280 290 300
YVFQGIDGKN IKMSSTENCY KVEAKANLSK SLRDTAVRLA ELGWLHNKIR
310 320 330 340 350
KYADQRSLDR SFGLVGQSFC AALHQELKEY YRLLSVLHSQ LQLEDDQGVN
360 370 380 390 400
VGLESSLTLR RLLVWTYDPK IRLKTLAALV DHCQGRKGGE LASAVHAYTK
410 420 430 440 450
TGDPYMKSLV QHILSLVSHP VLSFLYRWIY DGELEDTYHE FFVASDPTVK
460 470 480 490 500
TDRLWHDKYT LRKSMIPSFI TMDQSRKVLL IGKSINFLHQ VCHDQTPTTK
510 520 530 540 550
MIAVTKSAES PRDAADLFTD LENAFQGKID AAYFETSKYL LDVLNRKYSL
560 570 580 590 600
LEHMQAMRRY LLLGQGDFIR HLMDLLKSLL VTLGGMSSAW ITTSTDQLPL

CSHESA
Length:606
Mass (Da):67,899
Last modified:April 20, 2010 - v1
Checksum:iCD977E49B68C237A
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JUU7A0A0G2JUU7_RAT
Gamma-tubulin complex component
Tubgcp3
902Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC127756 Genomic DNA No translation available.
CH473970 Genomic DNA Translation: EDM08853.1
RefSeqiNP_001100793.1, NM_001107323.1
UniGeneiRn.99777

Genome annotation databases

EnsembliENSRNOT00000068416; ENSRNOP00000060338; ENSRNOG00000017085
GeneIDi306599
KEGGirno:306599

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC127756 Genomic DNA No translation available.
CH473970 Genomic DNA Translation: EDM08853.1
RefSeqiNP_001100793.1, NM_001107323.1
UniGeneiRn.99777

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000060338

Proteomic databases

PRIDEiD3ZMR7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000068416; ENSRNOP00000060338; ENSRNOG00000017085
GeneIDi306599
KEGGirno:306599

Organism-specific databases

CTDi10426
RGDi1305726 Tubgcp3

Phylogenomic databases

eggNOGiKOG2000 Eukaryota
ENOG410XQ5B LUCA
GeneTreeiENSGT00850000132278
KOiK16570

Enzyme and pathway databases

ReactomeiR-RNO-380270 Recruitment of mitotic centrosome proteins and complexes
R-RNO-380320 Recruitment of NuMA to mitotic centrosomes

Gene expression databases

BgeeiENSRNOG00000017085 Expressed in 9 organ(s), highest expression level in spleen
ExpressionAtlasiD3ZMR7 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR007259 GCP
PANTHERiPTHR19302 PTHR19302, 1 hit
PfamiView protein in Pfam
PF04130 Spc97_Spc98, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZMR7_RAT
AccessioniPrimary (citable) accession number: D3ZMR7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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