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UniProtKB - D3ZM61 (D3ZM61_RAT)
Protein
Submitted name:
RCG31652, isoform CRA_b
Gene
Zfp653
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- AF-2 domain binding Source: RGD
- DNA-binding transcription factor binding Source: Ensembl
- transcription coregulator activity Source: GO_Central
- transcription corepressor activity Source: RGD
GO - Biological processi
- extracellular negative regulation of signal transduction Source: RGD
- negative regulation of nucleic acid-templated transcription Source: RGD
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: RCG31652, isoform CRA_bImportedSubmitted name: Zinc finger protein 653Imported |
Gene namesi | Name:Zfp653Imported ORF Names:rCG_31652Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1308754, Zfp653 |
Subcellular locationi
Extracellular region or secreted
- extracellular region Source: GOC
Nucleus
- nucleus Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000014065, Expressed in testis and 21 other tissues |
Interactioni
GO - Molecular functioni
- AF-2 domain binding Source: RGD
- DNA-binding transcription factor binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000018874 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 498 – 527 | C2H2-typeInterPro annotationAdd BLAST | 30 | |
Domaini | 528 – 555 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 556 – 583 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 586 – 614 | C2H2-typeInterPro annotationAdd BLAST | 29 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 46 | DisorderedSequence analysisAdd BLAST | 46 | |
Regioni | 93 – 115 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 174 – 235 | DisorderedSequence analysisAdd BLAST | 62 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 25 – 46 | Basic and acidic residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 189 – 209 | Polar residuesSequence analysisAdd BLAST | 21 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000160257 |
HOGENOMi | CLU_037389_0_0_1 |
OMAi | GAPLCPN |
OrthoDBi | 1318335at2759 |
TreeFami | TF332664 |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 3 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 5 hits |
SUPFAMi | SSF57667, SSF57667, 3 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 5 hits PS50157, ZINC_FINGER_C2H2_2, 4 hits |
i Sequence
Sequence statusi: Complete.
D3ZM61-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAERAPEPGA EAEAGAGGEA AAEEGAAGRK ARGRPRLTES DRARRRLESR
60 70 80 90 100
KKYDVRRVYL GEAHGPWVDL RRRSGWSDAK LAAYLISLER GQRSGRHGKP
110 120 130 140 150
WEQVPKKPKR KKRRRRNVNC LKNVVIWYED HKHRCPYEPH LAELDPTFGL
160 170 180 190 200
YTTAVWQCEA GHRYFQDLHS PLKPLSDSEP DSDKVGNGLA AGSSDSSSSS
210 220 230 240 250
SSSDSEEPPE TQPAKAPAAA AAVTPSSPTG SSGLITQEGV HIPFDVHHVE
260 270 280 290 300
SLAEQGTPLC QNPAGSGPEA LETVVCVPVP MQVGTGPGTL FENMPQEALG
310 320 330 340 350
EVVASCPVSG MVPGSQVIII AGPGYDALTA EGIHLNVAAG SGTPSSSLGE
360 370 380 390 400
EVSCAMMEGV AAYTQTEPEG TQHSTMDTTS IASIETKKEK EDLYMLKEEK
410 420 430 440 450
EDSVAPELAE LAATVPENTE AEAEVDGEEL DSSEMSAIIY EIPKEPEKRR
460 470 480 490 500
RSKRSRVMDA DGLLEMFHCP YEGCSQVYVA LSSFQNHVNL VHRKGKTKVC
510 520 530 540 550
PHPGCGKKFY LSNHLRRHMI IHSGVREFTC ETCGKSFKRK NHLEVHRRTH
560 570 580 590 600
TGETPLQCEI CGYQCRQRAS LNWHMKKHTA EVQYNFTCDR CGKRFEKLDS
610
VKFHTLKSHP DHKPA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07073372 Genomic DNA No translation available. CH473993 Genomic DNA Translation: EDL78238.1 |
RefSeqi | NP_001100277.1, NM_001106807.1 |
Genome annotation databases
Ensembli | ENSRNOT00000018874; ENSRNOP00000018874; ENSRNOG00000014065 |
GeneIDi | 300446 |
KEGGi | rno:300446 |
UCSCi | RGD:1308754, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07073372 Genomic DNA No translation available. CH473993 Genomic DNA Translation: EDL78238.1 |
RefSeqi | NP_001100277.1, NM_001106807.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000018874 |
Genome annotation databases
Ensembli | ENSRNOT00000018874; ENSRNOP00000018874; ENSRNOG00000014065 |
GeneIDi | 300446 |
KEGGi | rno:300446 |
UCSCi | RGD:1308754, rat |
Organism-specific databases
CTDi | 319601 |
RGDi | 1308754, Zfp653 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000160257 |
HOGENOMi | CLU_037389_0_0_1 |
OMAi | GAPLCPN |
OrthoDBi | 1318335at2759 |
TreeFami | TF332664 |
Gene expression databases
Bgeei | ENSRNOG00000014065, Expressed in testis and 21 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 3 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 5 hits |
SUPFAMi | SSF57667, SSF57667, 3 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 5 hits PS50157, ZINC_FINGER_C2H2_2, 4 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | D3ZM61_RAT | |
Accessioni | D3ZM61Primary (citable) accession number: D3ZM61 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 3, 2013 | |
Last modified: | January 19, 2022 | |
This is version 77 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |