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Protein
Submitted name:

Lamin B2

Gene

Lmnb2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Lamin B2Imported
Gene namesi
Name:Lmnb2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1563803 Lmnb2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Intermediate filamentPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiD3ZLC1
PeptideAtlasiD3ZLC1
PRIDEiD3ZLC1

Expressioni

Gene expression databases

BgeeiENSRNOG00000025742 Expressed in 9 organ(s), highest expression level in testis
GenevisibleiD3ZLC1 RN

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000022336

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 398IF rodInterPro annotationAdd BLAST357
Domaini458 – 577LTDInterPro annotationAdd BLAST120

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili39 – 80Sequence analysisAdd BLAST42
Coiled coili89 – 137Sequence analysisAdd BLAST49
Coiled coili159 – 214Sequence analysisAdd BLAST56
Coiled coili296 – 376Sequence analysisAdd BLAST81

Sequence similaritiesi

Belongs to the intermediate filament family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0977 Eukaryota
ENOG410Y2H6 LUCA
GeneTreeiENSGT00910000143989
InParanoidiD3ZLC1
KOiK07611
OMAiEEIAYKF
OrthoDBiEOG091G063B
TreeFamiTF101181

Family and domain databases

Gene3Di2.60.40.1260, 1 hit
InterProiView protein in InterPro
IPR001664 IF
IPR039008 IF_rod_dom
IPR001322 Lamin_tail_dom
IPR036415 Lamin_tail_dom_sf
PANTHERiPTHR23239 PTHR23239, 1 hit
PfamiView protein in Pfam
PF00038 Filament, 1 hit
PF00932 LTD, 1 hit
SMARTiView protein in SMART
SM01391 Filament, 1 hit
SUPFAMiSSF74853 SSF74853, 1 hit
PROSITEiView protein in PROSITE
PS51842 IF_ROD_2, 1 hit
PS51841 LTD, 1 hit

Sequencei

Sequence statusi: Complete.

D3ZLC1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAPDPGSSA DPPAAATAMA SLPPRAGSAT PLSPTRLSRL QEKEELRELN
60 70 80 90 100
DRLAHYIDRV RALELENDKL LLRISEKEEV TTREVSGIKT LYESELADAR
110 120 130 140 150
RVLDETARER ARLQIEIGKV QAELEEAKKS AKKREGELTV ARGRVKDLES
160 170 180 190 200
LFHRSEAELA AALGDKHVLE TEVAELRAQL AKAEDGHAVA KKQLEKETLM
210 220 230 240 250
RVDLENHCQS LQEELAFSKS VFEEEVQETR RRHERHLVEV DSSRQQEYDF
260 270 280 290 300
KIAQALEELR SQHDEQVRLY RLELEQTYQA KLDNTKLISD QNDKAARAAR
310 320 330 340 350
EELKEARMRV ESLSYQLSGL QKQASAAEDH IRELEEALAG ERDKFRNMLD
360 370 380 390 400
AKEQEMAEVR DAMQQQLAEY QELLDIKLAL DMEICSYRKL LEGEEERLKL
410 420 430 440 450
SPSPSSRVTI SLATSSSSSS SSSGVGMSLG RGRSKRQRLE TEDTPGSPSS
460 470 480 490 500
ASSVSSGSRL AQQAGATGVV NIDEVDLEGR FVRLKNSSDK DQSLGNWRIK
510 520 530 540 550
KQVLEGEDIA YKFTPKYVLR AGQTVTVWAA GAGATHSPPS TLVWKNQSSW
560 570 580 590 600
GSGENFRTVL VNADGEEVAV QAAKPPSVQG HESREEEEEA EAEFGEEDLF
610
HQQGDPRTTS RGCRMM
Length:616
Mass (Da):68,851
Last modified:July 22, 2015 - v2
Checksum:i5D0F876C0CE2E398
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC103000 Genomic DNA No translation available.
RefSeqiNP_001292164.1, NM_001305235.1
XP_008763370.1, XM_008765148.2
XP_008763371.1, XM_008765149.2
UniGeneiRn.12408

Genome annotation databases

EnsembliENSRNOT00000022336; ENSRNOP00000022336; ENSRNOG00000025742
GeneIDi299625
KEGGirno:299625
UCSCiRGD:1563803 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC103000 Genomic DNA No translation available.
RefSeqiNP_001292164.1, NM_001305235.1
XP_008763370.1, XM_008765148.2
XP_008763371.1, XM_008765149.2
UniGeneiRn.12408

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000022336

Proteomic databases

PaxDbiD3ZLC1
PeptideAtlasiD3ZLC1
PRIDEiD3ZLC1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000022336; ENSRNOP00000022336; ENSRNOG00000025742
GeneIDi299625
KEGGirno:299625
UCSCiRGD:1563803 rat

Organism-specific databases

CTDi84823
RGDi1563803 Lmnb2

Phylogenomic databases

eggNOGiKOG0977 Eukaryota
ENOG410Y2H6 LUCA
GeneTreeiENSGT00910000143989
InParanoidiD3ZLC1
KOiK07611
OMAiEEIAYKF
OrthoDBiEOG091G063B
TreeFamiTF101181

Gene expression databases

BgeeiENSRNOG00000025742 Expressed in 9 organ(s), highest expression level in testis
GenevisibleiD3ZLC1 RN

Family and domain databases

Gene3Di2.60.40.1260, 1 hit
InterProiView protein in InterPro
IPR001664 IF
IPR039008 IF_rod_dom
IPR001322 Lamin_tail_dom
IPR036415 Lamin_tail_dom_sf
PANTHERiPTHR23239 PTHR23239, 1 hit
PfamiView protein in Pfam
PF00038 Filament, 1 hit
PF00932 LTD, 1 hit
SMARTiView protein in SMART
SM01391 Filament, 1 hit
SUPFAMiSSF74853 SSF74853, 1 hit
PROSITEiView protein in PROSITE
PS51842 IF_ROD_2, 1 hit
PS51841 LTD, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZLC1_RAT
AccessioniPrimary (citable) accession number: D3ZLC1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: November 7, 2018
This is version 68 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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