Glis2

Functionⁱ

GO - Molecular functionⁱ

RNA polymerase II regulatory region sequence-specific DNA binding Source: Ensembl
transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cell differentiation involved in kidney development Source: Ensembl
negative regulation of DNA-binding transcription factor activity Source: Ensembl
negative regulation of smoothened signaling pathway Source: Ensembl
negative regulation of transcription by RNA polymerase II Source: Ensembl
positive regulation of protein localization to nucleus Source: Ensembl
regulation of transcription from RNA polymerase II promoter involved in kidney development Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: GLIS family zinc finger 2Imported Submitted name: GLIS family zinc finger 2 (Predicted), isoform CRA_aImported
Gene namesⁱ	Name:Glis2Imported Synonyms:Glis2_predictedImported ORF Names:rCG_49824Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 10

Organism-specific databases

Rat genome database More...RGDⁱ	1309177 Glis2

RGDⁱ

1309177 Glis2

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

PRIDEⁱ	D3ZIA9

PRIDEⁱ

D3ZIA9

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000004766 Expressed in 10 organ(s), highest expression level in adult mammalian kidney

Bgeeⁱ

ENSRNOG00000004766 Expressed in 10 organ(s), highest expression level in adult mammalian kidney

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000006680

STRINGⁱ

10116.ENSRNOP00000006680

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	202 – 234	C2H2-typeInterPro annotationAdd BLAST	33
Domainⁱ	235 – 262	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	263 – 292	C2H2-typeInterPro annotationAdd BLAST	30
Domainⁱ	293 – 317	C2H2-typeInterPro annotationAdd BLAST	25

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00900000140802
KEGG Orthology (KO) More...KOⁱ	K09233
OMAⁱ	DKCLSPE
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0IZP
TreeFamⁱ	TF351425

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 2 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 3 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

D3ZIA9-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MHSLDEPLDL KLSITKLRAA REKRERTLGV PRHHALHREL GLVDDSPTPG 
        60         70         80         90        100
SPGSPPPGFL LNPKFPEKLD GRFSAAPLVD LSLSPPSGLD SPNGSSSLSP 
       110        120        130        140        150
ERQGNGDLPP LPTAVDFQPL RYLDGVPSSF QFFLPLGSGG ALHLPASSFL 
       160        170        180        190        200
TPPKDKCLSP ELPLAKQLVC RWAKCNQLFE LLQDLVDHVN DHHVKPEQDA 
       210        220        230        240        250
RYCCHWEGCA RHGRGFNARY KMLIHIRTHT NEKPHRCPTC NKSFSRLENL 
       260        270        280        290        300
KIHNRSHTGE KPYVCPYEGC NKRYSNSSDR FKHTRTHYVD KPYYCKMPGC 
       310        320        330        340        350
HKRYTDPSSL RKHIKAHGHF VSHEQQELLQ LRPPPKPPLP TPDSGSYVSG 
       360        370        380        390        400
AQIIIPNPAA LFGGPSLPGL PLPLAPGPLD LSALACGNGG GGGGGMGPGL 
       410        420        430        440        450
PGSVLPLNLA KNPLLPSPFG AGGLGLPVVS LLGGSAGSKA EGEKGRGSVP 
       460        470        480        490        500
ARVLGLEDHK TSLERTERSR SRPSPDGLPL LPGTVLDLST GNSAASSPEA 
       510        520 
LTPGWVVIPP GSVLLKPAVV N

Length:521

Mass (Da):55,895

Last modified:April 20, 2010 - v1

Checksum:ⁱ36693D47C529E8C6

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07029167 Genomic DNA No translation available. CH474017 Genomic DNA Translation: EDL96297.1 CH474017 Genomic DNA Translation: EDL96298.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001100448.1, NM_001106978.1 XP_017452708.1, XM_017597219.1
UniGeneⁱ	Rn.166996

Genome annotation databases

Ensemblⁱ	ENSRNOT00000006680; ENSRNOP00000006680; ENSRNOG00000004766
GeneIDⁱ	302946
KEGGⁱ	rno:302946
UCSC genome browser More...UCSCⁱ	RGD:1309177 rat

Protein	Similar proteins		Species	Score	Length	Source
D3ZIA9	Zinc finger protein GLIS2		MOUSE		521	UniRef90_Q8VDL9
Zinc finger protein GLIS2		HUMAN		524
GLIS family zinc finger 2		CANLF		627
Zinc finger protein GLIS2		CRIGR		549
Uncharacterized protein		NEOLE		530
+112

Protein	Similar proteins		Species	Score	Length	Source
D3ZIA9	Zinc finger protein GLIS2		MOUSE		521	UniRef50_Q8VDL9
Zinc finger protein GLIS2		HUMAN		524
GLIS family zinc finger 2		CANLF		627
Zinc finger protein GLIS2		CRIGR		549
Uncharacterized protein		NEOLE		530
+248

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07029167 Genomic DNA No translation available. CH474017 Genomic DNA Translation: EDL96297.1 CH474017 Genomic DNA Translation: EDL96298.1
RefSeqⁱ	NP_001100448.1, NM_001106978.1 XP_017452708.1, XM_017597219.1
UniGeneⁱ	Rn.166996

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000006680

STRINGⁱ

10116.ENSRNOP00000006680

Proteomic databases

PRIDEⁱ	D3ZIA9

PRIDEⁱ

D3ZIA9

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000006680; ENSRNOP00000006680; ENSRNOG00000004766
GeneIDⁱ	302946
KEGGⁱ	rno:302946
UCSCⁱ	RGD:1309177 rat

Organism-specific databases

CTDⁱ	84662
RGDⁱ	1309177 Glis2

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00900000140802
KOⁱ	K09233
OMAⁱ	DKCLSPE
OrthoDBⁱ	EOG091G0IZP
TreeFamⁱ	TF351425

Gene expression databases

Bgeeⁱ	ENSRNOG00000004766 Expressed in 10 organ(s), highest expression level in adult mammalian kidney

Bgeeⁱ

ENSRNOG00000004766 Expressed in 10 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 2 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 3 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	D3ZIA9_RAT
Accessionⁱ	D3ZIA9Primary (citable) accession number: D3ZIA9
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 20, 2010
	Last sequence update:	April 20, 2010
	Last modified:	October 10, 2018
	This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - D3ZIA9 (D3ZIA9_RAT)

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GLIS family zinc finger 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ