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Protein

Kinesin-like protein

Gene

Kif3b

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi96 – 103ATPPROSITE-ProRule annotation8

GO - Molecular functioni

  • ATPase activity Source: GO_Central
  • ATP binding Source: UniProtKB-UniRule
  • intraciliary transport particle B binding Source: Ensembl
  • microtubule binding Source: RGD
  • microtubule motor activity Source: GO_Central
  • Rho GTPase binding Source: Ensembl

GO - Biological processi

  • microtubule-based movement Source: GO_Central
  • mitotic spindle assembly Source: Ensembl
  • positive regulation of cytokinesis Source: RGD

Keywordsi

Molecular functionMotor proteinPROSITE-ProRule annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-RNO-2132295 MHC class II antigen presentation
R-RNO-5620924 Intraflagellar transport
R-RNO-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-RNO-983189 Kinesins

Names & Taxonomyi

Protein namesi
Recommended name:
Kinesin-like proteinUniRule annotation
Gene namesi
Name:Kif3bImported
Synonyms:Kif3b_predictedImported
ORF Names:rCG_37464Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1306815 Kif3b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MicrotubuleUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiD3ZI07

Expressioni

Gene expression databases

BgeeiENSRNOG00000010361 Expressed in 9 organ(s), highest expression level in testis

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000013804

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 340Kinesin motorInterPro annotationAdd BLAST332

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili355 – 375Sequence analysisAdd BLAST21
Coiled coili436 – 473Sequence analysisAdd BLAST38
Coiled coili482 – 519Sequence analysisAdd BLAST38
Coiled coili541 – 579Sequence analysisAdd BLAST39

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0240 Eukaryota
COG5059 LUCA
GeneTreeiENSGT00930000150817
KOiK20196
OMAiDMPARTT
TreeFamiTF105223

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
PANTHERiPTHR24115 PTHR24115, 1 hit
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

Sequencei

Sequence statusi: Complete.

D3ZI07-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKLKSSESV RVVVRCRPMN GKEKAAAYDK VVDVDVKLGQ VSVKNPKGTS
60 70 80 90 100
HEMPKTFTFD AVYDWNAKQF ELYDETFRPL VDSVLQGFNG TIFAYGQTGT
110 120 130 140 150
GKTYTMEGVR GDPEKRGVIP NSFDHIFTHI SRSQNQQYLV RASYLEIYQE
160 170 180 190 200
EIRDLLSKDQ TKRLELKERP DTGVYVKDLS SFVTKSVKEI EHVMNVGNQN
210 220 230 240 250
RSVGATNMNE HSSRSHAIFV ITVECSEVGL DGENHIRVGK LNLVDLAGSE
260 270 280 290 300
RQAKTGAQGE RLKEATKINL SLSALGNVIS ALVDGKSTHI PYRDSKLTRL
310 320 330 340 350
LQDSLGGNAK TVMVANVGPA SYNVEETLTT LRYANRAKNI KNKPRVNEDP
360 370 380 390 400
KDALLREFQE EIARLKAQLE KRSIGRRKRR EKRREGGGSG GGGEEEEEEG
410 420 430 440 450
EEGEEEGDDK DDYWREQQEK LEIEKRAIVE DHSLVAEEKM RLLKEKEKKM
460 470 480 490 500
EDLRREKDAA EMLGAKIKAM ESKLLVGGKN IVDHTNEQQK ILEQKRQEIA
510 520 530 540 550
EQKRREREIQ QQMESRDEET LELKETYTSL QQEVDIKTKK LKKLFSKLQA
560 570 580 590 600
VKAEIHDLQE EHIKERQELE QTQNELTREL KLKHLIIENF IPLEEKNKIM
610 620 630 640 650
NRSFFDDEED HWKLHPITRL ENQQMMKRPV SAVGYKRPLS QHARMSMMIR
660 670 680 690 700
PEPRYRAENI MLLELDMPSR TTRDYEGPAI SPKVQAALDA ALQDEDEIQV
710 720 730 740
DASSFESTAN RKAKARPKSG RKSGASSSSS GNPASQFYPQ SRGLVPK
Length:747
Mass (Da):85,257
Last modified:April 20, 2010 - v1
Checksum:iB61B931C6F1B5E1C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07054336 Genomic DNA No translation available.
AABR07054337 Genomic DNA No translation available.
CH474050 Genomic DNA Translation: EDL86006.1
RefSeqiNP_001099999.1, NM_001106529.1
XP_006235349.1, XM_006235287.3
XP_006235350.1, XM_006235288.1
XP_006235351.1, XM_006235289.3
XP_017447091.1, XM_017591602.1
UniGeneiRn.41581

Genome annotation databases

EnsembliENSRNOT00000013804; ENSRNOP00000013804; ENSRNOG00000010361
ENSRNOT00000085757; ENSRNOP00000072820; ENSRNOG00000010361
GeneIDi296284
KEGGirno:296284

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07054336 Genomic DNA No translation available.
AABR07054337 Genomic DNA No translation available.
CH474050 Genomic DNA Translation: EDL86006.1
RefSeqiNP_001099999.1, NM_001106529.1
XP_006235349.1, XM_006235287.3
XP_006235350.1, XM_006235288.1
XP_006235351.1, XM_006235289.3
XP_017447091.1, XM_017591602.1
UniGeneiRn.41581

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000013804

Proteomic databases

PRIDEiD3ZI07

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000013804; ENSRNOP00000013804; ENSRNOG00000010361
ENSRNOT00000085757; ENSRNOP00000072820; ENSRNOG00000010361
GeneIDi296284
KEGGirno:296284

Organism-specific databases

CTDi9371
RGDi1306815 Kif3b

Phylogenomic databases

eggNOGiKOG0240 Eukaryota
COG5059 LUCA
GeneTreeiENSGT00930000150817
KOiK20196
OMAiDMPARTT
TreeFamiTF105223

Enzyme and pathway databases

ReactomeiR-RNO-2132295 MHC class II antigen presentation
R-RNO-5620924 Intraflagellar transport
R-RNO-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-RNO-983189 Kinesins

Gene expression databases

BgeeiENSRNOG00000010361 Expressed in 9 organ(s), highest expression level in testis

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
PANTHERiPTHR24115 PTHR24115, 1 hit
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZI07_RAT
AccessioniPrimary (citable) accession number: D3ZI07
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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