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Protein
Submitted name:

Kruppel-like factor 8

Gene

Klf8

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Kruppel-like factor 8Imported
Gene namesi
Name:Klf8Imported
Synonyms:Klf8-ps1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi1565831 Klf8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiD3ZGU0
PRIDEiD3ZGU0

Expressioni

Gene expression databases

BgeeiENSRNOG00000039057 Expressed in 7 organ(s), highest expression level in brain

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000050482

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini270 – 299C2H2-typeInterPro annotationAdd BLAST30
Domaini300 – 329C2H2-typeInterPro annotationAdd BLAST30
Domaini330 – 355C2H2-typeInterPro annotationAdd BLAST26

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00760000118998
InParanoidiD3ZGU0
KOiK09205
OMAiGQQILHL
OrthoDBiEOG091G1BN0
PhylomeDBiD3ZGU0
TreeFamiTF350556

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 3 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits

Sequencei

Sequence statusi: Complete.

D3ZGU0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDKFINNMDV RIKTESDSME VFKQVTGPVP TRDPSVRGDR RNMTSPPFLA
60 70 80 90 100
ASPMENPALF NDIKIEPPEE LLESDFNTPQ VEPVDLSFHK PKAPLQPASM
110 120 130 140 150
LQAPIRPPKP PTAPQAIMVS TSADTVTSAA IPTVLTPGSI LASSQGTGGQ
160 170 180 190 200
PILHVIHTIP SVSLPNKMSG LKTIPLVVQS LPMVYTSLPA DGSPAAITVP
210 220 230 240 250
LIGGDGKSAG SVKVDPASMC PLEFPSDSDE SAIESGSSAL QSLQGFHHEP
260 270 280 290 300
ATMVHMQGEE SLDLKRRRIH QCDFAGCSKV YTKSSHLKAH RRIHTGEKPY
310 320 330 340 350
KCTWDGCSWK FARSDELTRH FRKHTGIKPF RCTDCNRSFS RSDHLSLHRR

RHDTM
Length:355
Mass (Da):38,871
Last modified:April 20, 2010 - v1
Checksum:i5E4693536AC78804
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07037335 Genomic DNA No translation available.
AABR07037336 Genomic DNA No translation available.
AABR07037337 Genomic DNA No translation available.
AABR07037338 Genomic DNA No translation available.
RefSeqiXP_008756602.1, XM_008758380.2
XP_008756603.1, XM_008758381.1
XP_008756604.1, XM_008758382.2
XP_008756605.1, XM_008758383.2
XP_008771325.1, XM_008773103.2
XP_008771326.1, XM_008773104.1
XP_008771327.1, XM_008773105.2
XP_008771328.1, XM_008773106.2
XP_017443675.1, XM_017588186.1
XP_017443676.1, XM_017588187.1
XP_017443677.1, XM_017588188.1
XP_017443678.1, XM_017588189.1
XP_017443679.1, XM_017588190.1
XP_017443680.1, XM_017588191.1
XP_017443681.1, XM_017588192.1
XP_017443682.1, XM_017588193.1
XP_017457752.1, XM_017602263.1
XP_017457753.1, XM_017602264.1
XP_017457754.1, XM_017602265.1
XP_017457755.1, XM_017602266.1
XP_017457756.1, XM_017602267.1
XP_017457757.1, XM_017602268.1
XP_017457758.1, XM_017602269.1
XP_017457759.1, XM_017602270.1

Genome annotation databases

EnsembliENSRNOT00000041039; ENSRNOP00000050482; ENSRNOG00000039057
GeneIDi302582
KEGGirno:302582

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07037335 Genomic DNA No translation available.
AABR07037336 Genomic DNA No translation available.
AABR07037337 Genomic DNA No translation available.
AABR07037338 Genomic DNA No translation available.
RefSeqiXP_008756602.1, XM_008758380.2
XP_008756603.1, XM_008758381.1
XP_008756604.1, XM_008758382.2
XP_008756605.1, XM_008758383.2
XP_008771325.1, XM_008773103.2
XP_008771326.1, XM_008773104.1
XP_008771327.1, XM_008773105.2
XP_008771328.1, XM_008773106.2
XP_017443675.1, XM_017588186.1
XP_017443676.1, XM_017588187.1
XP_017443677.1, XM_017588188.1
XP_017443678.1, XM_017588189.1
XP_017443679.1, XM_017588190.1
XP_017443680.1, XM_017588191.1
XP_017443681.1, XM_017588192.1
XP_017443682.1, XM_017588193.1
XP_017457752.1, XM_017602263.1
XP_017457753.1, XM_017602264.1
XP_017457754.1, XM_017602265.1
XP_017457755.1, XM_017602266.1
XP_017457756.1, XM_017602267.1
XP_017457757.1, XM_017602268.1
XP_017457758.1, XM_017602269.1
XP_017457759.1, XM_017602270.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000050482

Proteomic databases

PaxDbiD3ZGU0
PRIDEiD3ZGU0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000041039; ENSRNOP00000050482; ENSRNOG00000039057
GeneIDi302582
KEGGirno:302582

Organism-specific databases

CTDi11279
RGDi1565831 Klf8

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00760000118998
InParanoidiD3ZGU0
KOiK09205
OMAiGQQILHL
OrthoDBiEOG091G1BN0
PhylomeDBiD3ZGU0
TreeFamiTF350556

Gene expression databases

BgeeiENSRNOG00000039057 Expressed in 7 organ(s), highest expression level in brain

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 3 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZGU0_RAT
AccessioniPrimary (citable) accession number: D3ZGU0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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