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Protein
Submitted name:

Kruppel-like factor 12

Gene

Klf12

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Kruppel-like factor 12Imported
Submitted name:
Kruppel-like factor 12 (Predicted), isoform CRA_aImported
Gene namesi
Name:Klf12Imported
Synonyms:Klf12_predictedImported
ORF Names:rCG_36965Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 15

Organism-specific databases

RGDi1309204 Klf12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiD3ZG44

Expressioni

Gene expression databases

BgeeiENSRNOG00000009145 Expressed in 9 organ(s), highest expression level in liver
ExpressionAtlasiD3ZG44 baseline and differential
GenevisibleiD3ZG44 RN

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000012424

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini334 – 363C2H2-typeInterPro annotationAdd BLAST30
Domaini364 – 393C2H2-typeInterPro annotationAdd BLAST30
Domaini394 – 416C2H2-typeInterPro annotationAdd BLAST23

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00760000118998
InParanoidiD3ZG44
KOiK09205
OMAiMYTTAVR
OrthoDBiEOG091G1BN0
TreeFamiTF350556

Family and domain databases

InterProiView protein in InterPro
IPR030447 KLF12
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR44639 PTHR44639, 1 hit
PfamiView protein in Pfam
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 3 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

D3ZG44-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNIHTKRKII KNLTTLENRM LMFDGMPAVR VKTELLESEQ GSPNVHNYPD
60 70 80 90 100
MEAIPLLLNN VKGEPPEDSL PVDHFQTQTE PVDLSINKAR TSPTAASSSP
110 120 130 140 150
VSMTASASSP SSTSTSSSSS SRPASSPTVI TSVSSASSSS TVLSPGPLVA
160 170 180 190 200
SASGMGGQQF LHIIHPVPPS SPMNLQSNKL SHVHRIPVVV QSVPVVYTAV
210 220 230 240 250
RSPGNVNNTI VVPLLEDGRS HGKVQFCTLI VIYYICLFFP AQMEPRGLSP
260 270 280 290 300
RQSKSDSDDD DLPNVTLDSV NETGSTALSI ARAVQEVHPS PVSRVRGNRM
310 320 330 340 350
NNQKFACSIS PFSIESTRRQ RRSESPDSRK RRIHRCDFEG CNKVYTKSSH
360 370 380 390 400
LKAHRRTHTG EKPYKCTWEG CTWKFARSDE LTRHYRKHTG VKPFKCADCD
410
RSFSRSDHLA LHRRRHMLV
Length:419
Mass (Da):46,289
Last modified:July 22, 2015 - v3
Checksum:iCCA852DB43DB58DF
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2K610A0A0G2K610_RAT
Kruppel-like factor 12
Klf12 Klf12_predicted, rCG_36965
402Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07019024 Genomic DNA No translation available.
AABR07019025 Genomic DNA No translation available.
AABR07019026 Genomic DNA No translation available.
AABR07019027 Genomic DNA No translation available.
AABR07019028 Genomic DNA No translation available.
AABR07019029 Genomic DNA No translation available.
AABR07019030 Genomic DNA No translation available.
AABR07019031 Genomic DNA No translation available.
CH473951 Genomic DNA Translation: EDM02426.1
RefSeqiNP_001100751.1, NM_001107281.1
UniGeneiRn.61602

Genome annotation databases

EnsembliENSRNOT00000012424; ENSRNOP00000012424; ENSRNOG00000009145
GeneIDi306110
KEGGirno:306110
UCSCiRGD:1309204 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07019024 Genomic DNA No translation available.
AABR07019025 Genomic DNA No translation available.
AABR07019026 Genomic DNA No translation available.
AABR07019027 Genomic DNA No translation available.
AABR07019028 Genomic DNA No translation available.
AABR07019029 Genomic DNA No translation available.
AABR07019030 Genomic DNA No translation available.
AABR07019031 Genomic DNA No translation available.
CH473951 Genomic DNA Translation: EDM02426.1
RefSeqiNP_001100751.1, NM_001107281.1
UniGeneiRn.61602

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000012424

Proteomic databases

PRIDEiD3ZG44

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000012424; ENSRNOP00000012424; ENSRNOG00000009145
GeneIDi306110
KEGGirno:306110
UCSCiRGD:1309204 rat

Organism-specific databases

CTDi11278
RGDi1309204 Klf12

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00760000118998
InParanoidiD3ZG44
KOiK09205
OMAiMYTTAVR
OrthoDBiEOG091G1BN0
TreeFamiTF350556

Gene expression databases

BgeeiENSRNOG00000009145 Expressed in 9 organ(s), highest expression level in liver
ExpressionAtlasiD3ZG44 baseline and differential
GenevisibleiD3ZG44 RN

Family and domain databases

InterProiView protein in InterPro
IPR030447 KLF12
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR44639 PTHR44639, 1 hit
PfamiView protein in Pfam
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 3 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZG44_RAT
AccessioniPrimary (citable) accession number: D3ZG44
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: November 7, 2018
This is version 76 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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