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UniProtKB - D3ZG35 (D3ZG35_RAT)
Protein
Submitted name:
Zinc finger and BTB domain containing 26 (Predicted), isoform CRA_a
Gene
Zbtb26
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription repressor activity, RNA polymerase II-specific Source: GO_Central
- identical protein binding Source: RGD
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific double-stranded DNA binding Source: RGD
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger and BTB domain containing 26 (Predicted), isoform CRA_aImportedSubmitted name: Zinc finger and BTB domain-containing 26Imported |
Gene namesi | ORF Names:rCG_37712Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1308561, Zbtb26 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000009346, Expressed in liver and 20 other tissues |
Interactioni
GO - Molecular functioni
- identical protein binding Source: RGD
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000012433 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 44 – 108 | BTBInterPro annotationAdd BLAST | 65 | |
Domaini | 284 – 306 | C2H2-typeInterPro annotationAdd BLAST | 23 | |
Domaini | 309 – 336 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 337 – 364 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 365 – 388 | C2H2-typeInterPro annotationAdd BLAST | 24 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 142 – 227 | DisorderedSequence analysisAdd BLAST | 86 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 147 – 165 | Polar residuesSequence analysisAdd BLAST | 19 | |
Compositional biasi | 178 – 212 | Basic and acidic residuesSequence analysisAdd BLAST | 35 | |
Compositional biasi | 213 – 227 | Polar residuesSequence analysisAdd BLAST | 15 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000157920 |
HOGENOMi | CLU_037856_1_0_1 |
OMAi | RGIDKGL |
OrthoDBi | 1318335at2759 |
TreeFami | TF333162 |
Family and domain databases
Gene3Di | 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF00096, zf-C2H2, 4 hits |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 4 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 4 hits |
i Sequence
Sequence statusi: Complete.
D3ZG35-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAFPPGLSA KMSERSDLLH FKFENYGDSM LQKMNKLREE NKFCDVTVLI
60 70 80 90 100
DDVEVQGHKI VFAAGSPFLR DQFLLNDSRE VKISILQSSE VGRQLLLSCY
110 120 130 140 150
SGVLEFPEME LVNYLTAASF LQMSHIVERC TQALWKFIKP KQPMDSKEGS
160 170 180 190 200
EPQSASPQSK EQQGDARGSP KQDLPCIHPS EDSMDMEDSD IQIVKVESIG
210 220 230 240 250
DVSEDRSKKD QNQYISSEPT ALHSSEPQHS LINSTVENRV NELDQSHLHN
260 270 280 290 300
YALSYTGNDD IIMTSKDVFG PNIRGVDKGL QWHHQCPKCT RVFRHLENYA
310 320 330 340 350
NHLKMHKLFM CLLCGKTFTQ KGNLHRHMRV HAGIKPFQCK ICGKTFSQKC
360 370 380 390 400
SLQDHLNLHS GDKPHKCNYC DMVFAHKPVL RKHLKQLHGK NSFDNANERS
410 420 430 440 450
VQDLTVDFDS FACTTVTDSN CQPQPDATQV LDAGKLTQAV LSLRSDSTCV
N
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07051793 Genomic DNA No translation available. CH473983 Genomic DNA Translation: EDM00527.1 |
RefSeqi | NP_001101310.1, NM_001107840.1 |
Genome annotation databases
Ensembli | ENSRNOT00000012433; ENSRNOP00000012433; ENSRNOG00000009346 |
GeneIDi | 311910 |
KEGGi | rno:311910 |
UCSCi | RGD:1308561, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07051793 Genomic DNA No translation available. CH473983 Genomic DNA Translation: EDM00527.1 |
RefSeqi | NP_001101310.1, NM_001107840.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000012433 |
Genome annotation databases
Ensembli | ENSRNOT00000012433; ENSRNOP00000012433; ENSRNOG00000009346 |
GeneIDi | 311910 |
KEGGi | rno:311910 |
UCSCi | RGD:1308561, rat |
Organism-specific databases
CTDi | 57684 |
RGDi | 1308561, Zbtb26 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000157920 |
HOGENOMi | CLU_037856_1_0_1 |
OMAi | RGIDKGL |
OrthoDBi | 1318335at2759 |
TreeFami | TF333162 |
Gene expression databases
Bgeei | ENSRNOG00000009346, Expressed in liver and 20 other tissues |
Family and domain databases
Gene3Di | 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR011333, SKP1/BTB/POZ_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF00096, zf-C2H2, 4 hits |
SMARTi | View protein in SMART SM00225, BTB, 1 hit SM00355, ZnF_C2H2, 4 hits |
SUPFAMi | SSF54695, SSF54695, 1 hit SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 4 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | D3ZG35_RAT | |
Accessioni | D3ZG35Primary (citable) accession number: D3ZG35 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 20, 2010 | |
Last modified: | January 19, 2022 | |
This is version 90 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |