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Protein
Submitted name:

Calmegin

Gene

Clgn

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
CalmeginImported
Submitted name:
RCG51682Imported
Gene namesi
Name:ClgnImported
ORF Names:rCG_51682Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 19

Organism-specific databases

RGDi1592643 Clgn

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei471 – 492HelicalUniRule annotationAdd BLAST22

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19UniRule annotationAdd BLAST19
ChainiPRO_501521008720 – 611UniRule annotationAdd BLAST592

Proteomic databases

PRIDEiD3ZFS2

Expressioni

Gene expression databases

BgeeiENSRNOG00000003755 Expressed in 7 organ(s), highest expression level in testis

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000005071

Family & Domainsi

Sequence similaritiesi

Belongs to the calreticulin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG0675 Eukaryota
ENOG410XP7T LUCA
GeneTreeiENSGT00430000030841
KOiK09551
OMAiKTSYTIM
OrthoDBiEOG091G04SS
TreeFamiTF300618

Family and domain databases

Gene3Di2.10.250.10, 1 hit
InterProiView protein in InterPro
IPR001580 Calret/calnex
IPR018124 Calret/calnex_CS
IPR009033 Calreticulin/calnexin_P_dom_sf
IPR013320 ConA-like_dom_sf
PANTHERiPTHR11073 PTHR11073, 1 hit
PfamiView protein in Pfam
PF00262 Calreticulin, 1 hit
PRINTSiPR00626 CALRETICULIN
SUPFAMiSSF49899 SSF49899, 1 hit
SSF63887 SSF63887, 1 hit
PROSITEiView protein in PROSITE
PS00803 CALRETICULIN_1, 1 hit
PS00804 CALRETICULIN_2, 1 hit
PS00805 CALRETICULIN_REPEAT, 1 hit

Sequencei

Sequence statusi: Complete.

D3ZFS2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHFQGVGLCL GLLFITAKAD FVDDGVEVED FSESSDESDF KDEPSSGTIK
60 70 80 90 100
YKTPQPIGEV YFTETFDSGN LSGWVLSKAK KDDMDSEISI YDGRWEIEEL
110 120 130 140 150
KENQVPGDRG LVLKSKAKHH AISAVLEKPF IFADKPLIVQ YEVNFQDGID
160 170 180 190 200
CGGAYVKLLA DTGDLILENF YDKTSYTIMF GPDKCGEDYK LHLIFRHKHP
210 220 230 240 250
KTGVFEEKHA KPPDVDLKEF FTDRKTHLYT LVMNPDDTFE ILIDQKVVNQ
260 270 280 290 300
GTLLEDVVPP INPPREIDDP NDRKPEEWDD RAKIPDPTAV KPEDWDEKEP
310 320 330 340 350
IQIEDPSAVK PDGWLDDEPK FIPNPKAEKP EDWSDSMDGE WEAPHIPNPA
360 370 380 390 400
CQIGCGEWKP PMIDNPKYKG IWRPPMINNP NYQGIWSPQK IPNPDYFEDD
410 420 430 440 450
HPFLLTSFSA LGLELWSMTP DIYFDNFIIC SEKEVADQWA ADGWELKIMV
460 470 480 490 500
ANANEPGVLR QLTTAAEERP WLWLMYLVMA GLPIALVTSF CWPRKVKKKY
510 520 530 540 550
EDIGPKKADL CQLPSKAALE QEPEEEKAPE KPEDLQEEKK PSETEVVIVE
560 570 580 590 600
KEVIGEPEEK SEEDAETIEG QEEMTKLSKS GSEDEMKDAD ESTGSGDAPV
610
KSLRKRRVRK D
Length:611
Mass (Da):69,472
Last modified:April 20, 2010 - v1
Checksum:i181AC6C9D77A20AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07072631 Genomic DNA No translation available.
AC102976 Genomic DNA No translation available.
CH473972 Genomic DNA Translation: EDL92280.1
RefSeqiNP_001102942.1, NM_001109472.1
UniGeneiRn.45703

Genome annotation databases

EnsembliENSRNOT00000005071; ENSRNOP00000005071; ENSRNOG00000003755
GeneIDi685504
KEGGirno:685504

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07072631 Genomic DNA No translation available.
AC102976 Genomic DNA No translation available.
CH473972 Genomic DNA Translation: EDL92280.1
RefSeqiNP_001102942.1, NM_001109472.1
UniGeneiRn.45703

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000005071

Proteomic databases

PRIDEiD3ZFS2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000005071; ENSRNOP00000005071; ENSRNOG00000003755
GeneIDi685504
KEGGirno:685504

Organism-specific databases

CTDi1047
RGDi1592643 Clgn

Phylogenomic databases

eggNOGiKOG0675 Eukaryota
ENOG410XP7T LUCA
GeneTreeiENSGT00430000030841
KOiK09551
OMAiKTSYTIM
OrthoDBiEOG091G04SS
TreeFamiTF300618

Gene expression databases

BgeeiENSRNOG00000003755 Expressed in 7 organ(s), highest expression level in testis

Family and domain databases

Gene3Di2.10.250.10, 1 hit
InterProiView protein in InterPro
IPR001580 Calret/calnex
IPR018124 Calret/calnex_CS
IPR009033 Calreticulin/calnexin_P_dom_sf
IPR013320 ConA-like_dom_sf
PANTHERiPTHR11073 PTHR11073, 1 hit
PfamiView protein in Pfam
PF00262 Calreticulin, 1 hit
PRINTSiPR00626 CALRETICULIN
SUPFAMiSSF49899 SSF49899, 1 hit
SSF63887 SSF63887, 1 hit
PROSITEiView protein in PROSITE
PS00803 CALRETICULIN_1, 1 hit
PS00804 CALRETICULIN_2, 1 hit
PS00805 CALRETICULIN_REPEAT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZFS2_RAT
AccessioniPrimary (citable) accession number: D3ZFS2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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