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UniProtKB - D3ZF98 (D3ZF98_RAT)
Protein
Submitted name:
MAX network transcriptional repressor
Gene
Mnt
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- chromatin binding Source: RGD
- DNA binding Source: RGD
- DNA-binding transcription factor activity Source: RGD
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- DNA-binding transcription repressor activity, RNA polymerase II-specific Source: RGD
- protein dimerization activity Source: InterPro
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: RGD
GO - Biological processi
- cell aging Source: RGD
- negative regulation of apoptotic signaling pathway Source: RGD
- negative regulation of transcription by RNA polymerase II Source: RGD
- regulation of cell cycle Source: RGD
- regulation of transcription, DNA-templated Source: RGD
- regulation of transcription by RNA polymerase II Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: MAX network transcriptional repressor |
Gene namesi | Name:MntImported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1308683, Mnt |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000002894, Expressed in brain and 20 other tissues |
ExpressionAtlasi | D3ZF98, baseline and differential |
Interactioni
GO - Molecular functioni
- protein dimerization activity Source: InterPro
Protein-protein interaction databases
IntActi | D3ZF98, 1 interactor |
STRINGi | 10116.ENSRNOP00000003933 |
Family & Domainsi
Phylogenomic databases
eggNOGi | KOG2483, Eukaryota |
GeneTreei | ENSGT00510000048287 |
HOGENOMi | CLU_020165_1_0_1 |
InParanoidi | D3ZF98 |
TreeFami | TF315654 |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
D3ZF98-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSIETLLEAA RFLEWQAQQQ QRAREEQERL RLEREREREQ EQKRASNLAR
60 70 80 90 100
LAHALPVEEP RVEAPPLPLS PPAPPPAPPP PLATPAPLTV IPIPVVTNSP
110 120 130 140 150
QSLPPPPPLP PAAQPLPLAP RQPALVSTPG LSIKEPVPLP TRPQVPTPAP
160 170 180 190 200
LLPDSKTTVA PTGSPKPLQP LPTPILTIAP HPGVQPQLAP QQPPPPTLGT
210 220 230 240 250
LKLAPAEEAK SSEQKKRPGG RAHLKECFET LKRNIPNVDD KKTSNLSVLR
260 270 280 290 300
TALRYIQSLK RKEKEYEHEM ERLAREKIAT QQRLAELKHE LSQWMDVLEI
310 320 330 340 350
DRVLRQTGQP EDDQASTSTA SEGEDNVDEE MEGDRAGLGP PKLNHRPQPE
360 370 380 390 400
LLKAALPTPS TAPAPLPAHP HPHPHPVALS PAHLPVQQQP PQQKTPLPAP
410 420 430 440 450
PPPPATPTQT LVPAPAHLVA TAGGGSTVIA HTATTHASVI QTVNHVLQGP
460 470 480 490 500
GGKHIAHIAP SAPSPAVQLA PATPPIGHIT VHPATLNHVA HLGSQLPLYP
510 520 530 540 550
QPVAVSQPVA VSHIAHTLSH QQVNGTAGLG PPATVMAKPA VGAQVVHHPQ
560 570
LVGQTVLNPV TMVTMPSFPV STLKLA
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0U1RRY7 | A0A0U1RRY7_RAT | MAX network transcriptional repress... | Mnt | 590 | Annotation score: |
Genome annotation databases
Ensembli | ENSRNOT00000003933.6; ENSRNOP00000003933.5; ENSRNOG00000002894.8 |
Similar proteinsi
Cross-referencesi
3D structure databases
SMRi | D3ZF98 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | D3ZF98, 1 interactor |
STRINGi | 10116.ENSRNOP00000003933 |
Proteomic databases
PaxDbi | D3ZF98 |
Genome annotation databases
Ensembli | ENSRNOT00000003933.6; ENSRNOP00000003933.5; ENSRNOG00000002894.8 |
Organism-specific databases
RGDi | 1308683, Mnt |
Phylogenomic databases
eggNOGi | KOG2483, Eukaryota |
GeneTreei | ENSGT00510000048287 |
HOGENOMi | CLU_020165_1_0_1 |
InParanoidi | D3ZF98 |
TreeFami | TF315654 |
Miscellaneous databases
PROi | PR:D3ZF98 |
Gene expression databases
Bgeei | ENSRNOG00000002894, Expressed in brain and 20 other tissues |
ExpressionAtlasi | D3ZF98, baseline and differential |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | D3ZF98_RAT | |
Accessioni | D3ZF98Primary (citable) accession number: D3ZF98 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | May 25, 2022 | |
Last modified: | May 25, 2022 | |
This is version 71 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |