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Protein
Submitted name:

RCG50849

Gene

Rarg

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-383280 Nuclear Receptor transcription pathway
R-RNO-5362517 Signaling by Retinoic Acid

Names & Taxonomyi

Protein namesi
Submitted name:
RCG50849Imported
Submitted name:
Retinoic acid receptor, gammaImported
Gene namesi
Name:RargImported
ORF Names:rCG_50849Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1583230 Rarg

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiD3ZF61

Expressioni

Gene expression databases

BgeeiENSRNOG00000012499 Expressed in 9 organ(s), highest expression level in lung
ExpressionAtlasiD3ZF61 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiD3ZF61
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini87 – 162Nuclear receptorInterPro annotationAdd BLAST76
Domaini185 – 419NR LBDInterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00870000136372
KOiK08529
OMAiQKVSKAH

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR003078 Retinoic_acid_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01292 RETNOICACIDR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

D3ZF61-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATNKERLFA PNALGPGSGY PGAGFPFAFP GALRGSPPFE MLSPSFRGLG
60 70 80 90 100
QPDLPKEMAS LSVETQSTSS EEMVPSSPSP PPPPRVYKPC FVCNDKSSGY
110 120 130 140 150
HYGVSSCEGC KGFFRRSIQK NMVYTCHRDK NCIINKVTRN RCQYCRLQKC
160 170 180 190 200
FEVGMSKEAV RNDRNKKKKE VKEEGPPDNY ELSPQLEELI TKVSKAHQET
210 220 230 240 250
FPSLCQLGKY TTNSSADHRV QLDLGLWDKF SELATKCIIK IVEFAKRLPG
260 270 280 290 300
FTGLSIADQI TLLKAACLDI LMLRICTRYT PEQDTMTFSD GLTLNRTQMH
310 320 330 340 350
NAGFGPLTDL VFAFAGQLLP LEMDDTETGL LSAICLICGD RMDLEEPEKV
360 370 380 390 400
DKLQEPLLEA LRLYARRRRP SQPYMFPRML MKITDLRGIS TKGAERAITL
410 420 430 440 450
KMEIPGPMPP LIREMLENPE MFEDDSSKPG PHPKASSEDE APGSQGKRGQ

SPQPDQGP
Length:458
Mass (Da):51,016
Last modified:April 20, 2010 - v1
Checksum:i0AD290AE7C163E70
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3ZWV0D3ZWV0_RAT
Retinoic acid receptor, gamma
Rarg
485Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110347 Genomic DNA No translation available.
CH474035 Genomic DNA Translation: EDL86852.1
RefSeqiNP_001128721.1, NM_001135249.1
XP_008764007.1, XM_008765785.2
XP_008764008.1, XM_008765786.2
UniGeneiRn.198797

Genome annotation databases

EnsembliENSRNOT00000017096; ENSRNOP00000017096; ENSRNOG00000012499
GeneIDi685072
KEGGirno:685072

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110347 Genomic DNA No translation available.
CH474035 Genomic DNA Translation: EDL86852.1
RefSeqiNP_001128721.1, NM_001135249.1
XP_008764007.1, XM_008765785.2
XP_008764008.1, XM_008765786.2
UniGeneiRn.198797

3D structure databases

SMRiD3ZF61
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiD3ZF61

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000017096; ENSRNOP00000017096; ENSRNOG00000012499
GeneIDi685072
KEGGirno:685072

Organism-specific databases

CTDi5916
RGDi1583230 Rarg

Phylogenomic databases

GeneTreeiENSGT00870000136372
KOiK08529
OMAiQKVSKAH

Enzyme and pathway databases

ReactomeiR-RNO-383280 Nuclear Receptor transcription pathway
R-RNO-5362517 Signaling by Retinoic Acid

Gene expression databases

BgeeiENSRNOG00000012499 Expressed in 9 organ(s), highest expression level in lung
ExpressionAtlasiD3ZF61 baseline and differential

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR003078 Retinoic_acid_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01292 RETNOICACIDR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZF61_RAT
AccessioniPrimary (citable) accession number: D3ZF61
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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