Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 88 (07 Oct 2020)
Sequence version 2 (22 Jul 2015)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Phospholipid-transporting ATPase

Gene

Atp8b3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).UniRule annotationARBA annotation EC:7.6.2.1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTranslocaseUniRule annotationARBA annotation
LigandATP-bindingUniRule annotationARBA annotation, MagnesiumUniRule annotationARBA annotation, Metal-bindingARBA annotation, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-RNO-936837, Ion transport by P-type ATPases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phospholipid-transporting ATPaseUniRule annotation (EC:7.6.2.1UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Atp8b3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Rat genome database

More...
RGDi
1307622, Atp8b3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei69 – 86HelicalUniRule annotationAdd BLAST18
Transmembranei293 – 316HelicalUniRule annotationAdd BLAST24
Transmembranei340 – 366HelicalUniRule annotationAdd BLAST27
Transmembranei914 – 934HelicalUniRule annotationAdd BLAST21
Transmembranei946 – 966HelicalUniRule annotationAdd BLAST21
Transmembranei996 – 1019HelicalUniRule annotationAdd BLAST24
Transmembranei1031 – 1052HelicalUniRule annotationAdd BLAST22
Transmembranei1059 – 1087HelicalUniRule annotationAdd BLAST29
Transmembranei1107 – 1128HelicalUniRule annotationAdd BLAST22

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
D3ZE62

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
D3ZE62

PeptideAtlas

More...
PeptideAtlasi
D3ZE62

PRoteomics IDEntifications database

More...
PRIDEi
D3ZE62

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
D3ZE62

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
D3ZE62

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000024975, Expressed in testis and 16 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000031877

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini21 – 97PhoLip_ATPase_NInterPro annotationAdd BLAST77
Domaini883 – 1133PhoLip_ATPase_CInterPro annotationAdd BLAST251

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1230 – 1255DisorderedSequence analysisAdd BLAST26
Regioni1260 – 1279DisorderedSequence analysisAdd BLAST20
Regioni1300 – 1340DisorderedSequence analysisAdd BLAST41

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili626 – 646Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1315 – 1340PolarSequence analysisAdd BLAST26

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. [View classification]UniRule annotationARBA annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0206, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160463

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000846_3_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
D3ZE62

KEGG Orthology (KO)

More...
KOi
K01530

Identification of Orthologs from Complete Genome Data

More...
OMAi
HTVMAEW

Database of Orthologous Groups

More...
OrthoDBi
587717at2759

TreeFam database of animal gene trees

More...
TreeFami
TF300654

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.1110.10, 1 hit
3.40.50.1000, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR030349, ATP8B3
IPR023299, ATPase_P-typ_cyto_dom_N
IPR018303, ATPase_P-typ_P_site
IPR023298, ATPase_P-typ_TM_dom_sf
IPR008250, ATPase_P-typ_transduc_dom_A_sf
IPR036412, HAD-like_sf
IPR023214, HAD_sf
IPR006539, P-type_ATPase_IV
IPR032631, P-type_ATPase_N
IPR001757, P_typ_ATPase
IPR032630, P_typ_ATPase_c

The PANTHER Classification System

More...
PANTHERi
PTHR24092, PTHR24092, 1 hit
PTHR24092:SF78, PTHR24092:SF78, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16212, PhoLip_ATPase_C, 1 hit
PF16209, PhoLip_ATPase_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56784, SSF56784, 1 hit
SSF81653, SSF81653, 1 hit
SSF81660, SSF81660, 1 hit
SSF81665, SSF81665, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01652, ATPase-Plipid, 1 hit
TIGR01494, ATPase_P-type, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00154, ATPASE_E1_E2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

D3ZE62-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDDAHLEEDL EDKDTEFTWE VKANDRAYHK QFRKKGFLCW RQKKYKSNAI
60 70 80 90 100
HTAKYNVFSF LPLNLYEQFR RVSNLYFLFI IILQSIPEIS TLPWFTLFAP
110 120 130 140 150
LVCLLMIRAA RDLVDDIGRH RSDRIINNRP CQILKGKSFL WKKWKNLCVG
160 170 180 190 200
DVVCLSKDNI VPADLLLLAS TEPSSLCYLE TADIDGETNL KFRQALMVTH
210 220 230 240 250
HELTSPKKMA SFQGIVTCEE PNSRMHHFVG SLEWNSRKYP LDIGNLLLRG
260 270 280 290 300
CKIRNTDTCY GLVIYAGLDT KIMKNCGKIH LKRTKLDLMM NKLVILIFMS
310 320 330 340 350
LVIASMFLTL GFAFMVKEFK AKHHYMSSMQ GRTDAMDSFF IFWGFLILLS
360 370 380 390 400
VMVPMAMFII AEFIYLGNSI FINWDLSMYY EPLDIPAKAR STSLNDHLGQ
410 420 430 440 450
VQYIFSDKTG TLTQNIMTFK KCCINGCTYD SDDEHGTLRK RNPYSWNPFA
460 470 480 490 500
DGKLQFYNKE LESLVRGKQD RAVQEFWRLL AICHTVMVQE KDNQLLYQAA
510 520 530 540 550
SPDEEALVAA ARNFGYVFLS RTQDTITLVE LGEERVYQVL AMMDFNSVRK
560 570 580 590 600
RMSVLVRNPE GSICLYTKGA DTVILERLHH KGVMEATTEE VLAAFAEQTL
610 620 630 640 650
RTLCLAYKDV AEDAYKEWEP EHQEAALLLQ NRAQALHQVY NKLEQNLQLL
660 670 680 690 700
GVTAIEDKLQ DGVPETIRCL KKGNIKMWVL TGDKPETAVN IGFACQLLSE
710 720 730 740 750
NMSILEDKDI KGLLENYWDE NEHQRAFQTM THHNMALVIN GEFLDQLLLS
760 770 780 790 800
LRKEPRALVQ NAVVDEATQE PGVSALDFLQ ARRISQMWRN FGTTMATSQS
810 820 830 840 850
DASKTRESPE ERRERAFVDL ASKCQAVICC RVTPKQKALV VALVKKYQQV
860 870 880 890 900
VTLAIGDGAN DVNMIKTADI GVGLAGQEGM QAVQNSDYVL AQFCYLQRLL
910 920 930 940 950
LVHGRWSYMR ICKFLRYFFY KTVASMMAQI WFSLFNGFSA QPLYEGWFLA
960 970 980 990 1000
LFNLLYSTLP VLYIGLFEQD VTAEKSLKMP ELYTAGQKDE LFNYSIFVQA
1010 1020 1030 1040 1050
IAHGTITSLI NFFVTILVSY DMTKTGSSPD YQSFGVLVAI SSLLSITLEV
1060 1070 1080 1090 1100
ILVVKYWTLL FVGTVVVSLS SYVIFTSLTE SLLLFRISPK TFPFLFADYN
1110 1120 1130 1140 1150
VIREPSSLLV IVLNVTLNTL PMLAVRIIRR TVLKRHPKKE EEVPSEELTV
1160 1170 1180 1190 1200
EPAMRLRRGM PARRSSYAFS HHEGYANLIT QGTILRRHTH VDEFYGDTAC
1210 1220 1230 1240 1250
NSPNPSEEDV PWQHKESIFN PRKISILAKK RRQHYGKGSQ GEVHPNASSQ
1260 1270 1280 1290 1300
TTEKQTAINI DNHETKKLPT TTSAMSGQLQ VSSSEDQAFY SALSQYSLAS
1310 1320 1330 1340
RPERMDVRSS SWKGPLLRDS ASSRSSHLEV TTQLHSHTSS
Length:1,340
Mass (Da):152,940
Last modified:July 22, 2015 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i75CFA495AD80762B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC120291 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_001076355.1, XM_001076355.6
XP_234937.3, XM_234937.9

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000039813; ENSRNOP00000031877; ENSRNOG00000024975

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
299616

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:299616

UCSC genome browser

More...
UCSCi
RGD:1307622, rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120291 Genomic DNA No translation available.
RefSeqiXP_001076355.1, XM_001076355.6
XP_234937.3, XM_234937.9

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000031877

PTM databases

iPTMnetiD3ZE62
PhosphoSitePlusiD3ZE62

Proteomic databases

jPOSTiD3ZE62
PaxDbiD3ZE62
PeptideAtlasiD3ZE62
PRIDEiD3ZE62

Genome annotation databases

EnsembliENSRNOT00000039813; ENSRNOP00000031877; ENSRNOG00000024975
GeneIDi299616
KEGGirno:299616
UCSCiRGD:1307622, rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
148229
RGDi1307622, Atp8b3

Phylogenomic databases

eggNOGiKOG0206, Eukaryota
GeneTreeiENSGT00940000160463
HOGENOMiCLU_000846_3_2_1
InParanoidiD3ZE62
KOiK01530
OMAiHTVMAEW
OrthoDBi587717at2759
TreeFamiTF300654

Enzyme and pathway databases

ReactomeiR-RNO-936837, Ion transport by P-type ATPases

Miscellaneous databases

Protein Ontology

More...
PROi
PR:D3ZE62

Gene expression databases

BgeeiENSRNOG00000024975, Expressed in testis and 16 other tissues

Family and domain databases

Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR030349, ATP8B3
IPR023299, ATPase_P-typ_cyto_dom_N
IPR018303, ATPase_P-typ_P_site
IPR023298, ATPase_P-typ_TM_dom_sf
IPR008250, ATPase_P-typ_transduc_dom_A_sf
IPR036412, HAD-like_sf
IPR023214, HAD_sf
IPR006539, P-type_ATPase_IV
IPR032631, P-type_ATPase_N
IPR001757, P_typ_ATPase
IPR032630, P_typ_ATPase_c
PANTHERiPTHR24092, PTHR24092, 1 hit
PTHR24092:SF78, PTHR24092:SF78, 1 hit
PfamiView protein in Pfam
PF16212, PhoLip_ATPase_C, 1 hit
PF16209, PhoLip_ATPase_N, 1 hit
SUPFAMiSSF56784, SSF56784, 1 hit
SSF81653, SSF81653, 1 hit
SSF81660, SSF81660, 1 hit
SSF81665, SSF81665, 1 hit
TIGRFAMsiTIGR01652, ATPase-Plipid, 1 hit
TIGR01494, ATPase_P-type, 1 hit
PROSITEiView protein in PROSITE
PS00154, ATPASE_E1_E2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD3ZE62_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D3ZE62
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: July 22, 2015
Last modified: October 7, 2020
This is version 88 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again