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Protein
Submitted name:

Transmembrane protein 115

Gene

Tmem115

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • replicative cell aging Source: RGD
  • retrograde vesicle-mediated transport, Golgi to ER Source: GO_Central

Enzyme and pathway databases

ReactomeiR-RNO-6807878 COPI-mediated anterograde transport

Names & Taxonomyi

Protein namesi
Submitted name:
Transmembrane protein 115Imported
Submitted name:
Transmembrane protein 115 (Predicted)Imported
Gene namesi
Name:Tmem115Imported
Synonyms:Tmem115_predictedImported
ORF Names:rCG_25499Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi1310540 Tmem115

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 37HelicalSequence analysisAdd BLAST26
Transmembranei57 – 86HelicalSequence analysisAdd BLAST30
Transmembranei98 – 121HelicalSequence analysisAdd BLAST24
Transmembranei127 – 149HelicalSequence analysisAdd BLAST23
Transmembranei161 – 180HelicalSequence analysisAdd BLAST20
Transmembranei186 – 205HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiD3ZE59

Expressioni

Gene expression databases

BgeeiENSRNOG00000021899 Expressed in 10 organ(s), highest expression level in adult mammalian kidney

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000031879

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili281 – 301Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2890 Eukaryota
ENOG410XQM0 LUCA
GeneTreeiENSGT00390000002470
OMAiEIHFWEV
OrthoDBiEOG091G0B9B
TreeFamiTF315100

Family and domain databases

InterProiView protein in InterPro
IPR013861 DUF1751_Mem_euk
PANTHERiPTHR13377 PTHR13377, 1 hit
PfamiView protein in Pfam
PF08551 DUF1751, 1 hit

Sequencei

Sequence statusi: Complete.

D3ZE59-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQRALPGARQ HLGAILASAS VVVKALCAVV LFLYLLSFAV DTGCLAVTPG
60 70 80 90 100
YLFPPNFWIW TLATHGLMEQ HVWDVAISLA TVVVAGRLLE PLWGALELLI
110 120 130 140 150
FFSVVNVSVG LLGAFAYLLT YMASFNLVYL FTIRIHGALG FLGGVLVALK
160 170 180 190 200
QTMGDCVVLR VPQVRVSVVP MLLLALLLLL RLATLLQSPA LASYGFGLLS
210 220 230 240 250
SWVYLRFYQR HSRGRGDMAD HFAFATFFPE ILQPVVGLLA NLVHGLLVKV
260 270 280 290 300
KICQKTVKRY DVGAPSSITI SLPGTDPQDA ERRRQLALKA LNERLKRVED
310 320 330 340 350
QSAWPSMDDD EEEAGAKTDS PLPSEQASTP PGKGTAPEST LITFEAAPLL
Length:350
Mass (Da):38,054
Last modified:April 20, 2010 - v1
Checksum:i29107C53298BFDD5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139927 Genomic DNA No translation available.
CH473954 Genomic DNA Translation: EDL77255.1
RefSeqiNP_001102249.1, NM_001108779.1
UniGeneiRn.7749

Genome annotation databases

EnsembliENSRNOT00000032263; ENSRNOP00000031879; ENSRNOG00000021899
GeneIDi363136
KEGGirno:363136
UCSCiRGD:1310540 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139927 Genomic DNA No translation available.
CH473954 Genomic DNA Translation: EDL77255.1
RefSeqiNP_001102249.1, NM_001108779.1
UniGeneiRn.7749

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000031879

Proteomic databases

PRIDEiD3ZE59

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000032263; ENSRNOP00000031879; ENSRNOG00000021899
GeneIDi363136
KEGGirno:363136
UCSCiRGD:1310540 rat

Organism-specific databases

CTDi11070
RGDi1310540 Tmem115

Phylogenomic databases

eggNOGiKOG2890 Eukaryota
ENOG410XQM0 LUCA
GeneTreeiENSGT00390000002470
OMAiEIHFWEV
OrthoDBiEOG091G0B9B
TreeFamiTF315100

Enzyme and pathway databases

ReactomeiR-RNO-6807878 COPI-mediated anterograde transport

Gene expression databases

BgeeiENSRNOG00000021899 Expressed in 10 organ(s), highest expression level in adult mammalian kidney

Family and domain databases

InterProiView protein in InterPro
IPR013861 DUF1751_Mem_euk
PANTHERiPTHR13377 PTHR13377, 1 hit
PfamiView protein in Pfam
PF08551 DUF1751, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZE59_RAT
AccessioniPrimary (citable) accession number: D3ZE59
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: October 10, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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