Polycystic kidney disease 2-like 1 (Predicted)

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• calcium-activated potassium channel activity Source: Ensembl
• calcium channel activity Source: GO_Central
• calcium ion binding Source: Ensembl
• identical protein binding Source: Ensembl
• muscle alpha-actinin binding Source: Ensembl
• sodium channel activity Source: Ensembl
• sour taste receptor activity Source: Ensembl

GO - Biological processⁱ

• cellular response to acidic pH Source: Ensembl
• detection of mechanical stimulus Source: GO_Central
• protein homotrimerization Source: Ensembl
• smoothened signaling pathway Source: Ensembl

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

Topology

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componentⁱ

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

GO - Molecular functionⁱ

• identical protein binding Source: Ensembl
• muscle alpha-actinin binding Source: Ensembl

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Coiled coil

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MNIMENSKEQ ELQTLGSRVW DNPAYSSPPS PNGTPRICTV SSVALPETQP 
        60         70         80         90        100
KKPEVRRQEK TPRVPVSGCC LLICRGIRGL WGTTLTENTA ENRELYVKTT 
       110        120        130        140        150
LRELVVYIVF LVDVCLLTYG MTSSSAYYYT KVMSELFLHT PSESAVSFQT 
       160        170        180        190        200
ISSMSDFWDG PLLDSLYWTK WYNNQSLGSS SHSFIYYENL LLGVPRLRQL 
       210        220        230        240        250
RVRNDSCVVH EDFREDILNC YDVYSPDKED QLPFGPLNGT AWTYHSQNEL 
       260        270        280        290        300
GGSSHWGRLT SYSGGGYYLD LPGSRQASAE ALQGLQEGLW LDRGTRVVFI 
       310        320        330        340        350
DFSVYNANIN LFCILRLVVE FPATGGAIPS WQIRTVKLIR YVNNWDFFIV 
       360        370        380        390        400
GCEVIFCIFI FYYVVEEILE IRVHRFRYLS SVWNILDLVV ILLSIVAVGF 
       410        420        430        440        450
HVFRTLEVNR LMGELLQQPD TYPDFEFLAF WQTQYNNMNA VNLFFAWIKI 
       460        470        480        490        500
FKYISFNKTM TQLSSTLARC AKDILGFAIM FFIVFFAYAQ LGYLLFGTQV 
       510        520        530        540        550
ESFSTFVKCI FTQFRIILGD FDYNAIDNAN RILGPVYFIT YVFFVFFVLL 
       560        570        580        590        600
NMFLAIINDT YSEVKEELAG QRDQLQLSDL LKQSYSKTLQ RLRLRKERVS 
       610        620        630        640        650
DVQKVLKGGE PEIQFEDFTN TLRELTRRVL QLQRVLEGVV SQVDALSSKL 
       660        670 
KMLERKGELA PSPGMARGAS CLGEPL                           

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ