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UniProtKB - D3ZCK0 (D3ZCK0_RAT)
Protein
Submitted name:
Zinc finger with KRAB and SCAN domains 4
Gene
Zkscan4
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- identical protein binding Source: RGD
- metal ion binding Source: UniProtKB-KW
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
Reactomei | R-RNO-212436, Generic Transcription Pathway |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger with KRAB and SCAN domains 4Imported |
Gene namesi | Name:Zkscan4Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1309004, Zkscan4 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationARBA annotationExpressioni
Gene expression databases
Bgeei | ENSRNOG00000051823, Expressed in liver and 20 other tissues |
Interactioni
GO - Molecular functioni
- identical protein binding Source: RGD
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000024797 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 48 | SCAN boxInterPro annotationAdd BLAST | 48 | |
Domaini | 168 – 195 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 196 – 223 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 224 – 251 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 252 – 279 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 280 – 307 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 335 – 362 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 363 – 390 | C2H2-typeInterPro annotationAdd BLAST | 28 |
Sequence similaritiesi
Belongs to the krueppel C2H2-type zinc-finger protein family.ARBA annotation
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000159644 |
HOGENOMi | CLU_002678_49_4_1 |
OMAi | GHCREDA |
Family and domain databases
Gene3Di | 1.10.4020.10, 1 hit |
InterProi | View protein in InterPro IPR003309, SCAN_dom IPR038269, SCAN_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF02023, SCAN, 1 hit PF00096, zf-C2H2, 7 hits |
SMARTi | View protein in SMART SM00431, SCAN, 1 hit SM00355, ZnF_C2H2, 7 hits |
SUPFAMi | SSF57667, SSF57667, 4 hits |
PROSITEi | View protein in PROSITE PS50804, SCAN_BOX, 1 hit PS00028, ZINC_FINGER_C2H2_1, 7 hits PS50157, ZINC_FINGER_C2H2_2, 7 hits |
i Sequence
Sequence statusi: Complete.
D3ZCK0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
SKEQILELLV LEQFLTILPG ELQAWVREQH PDSGEEVVAL LEYLDRQLDE
60 70 80 90 100
TPPQVPTGEW SRELLCCKVA LVTSSQDSQS SHSQAMKSLF KHESQESLEC
110 120 130 140 150
SPLQARGLEM KPETRGLPLA EEYKEQKPEQ TVWFLGEDTV QISTSTEASE
160 170 180 190 200
QEGKLQTTQK NATGNRRFYC HECGKSFAQS SGLTKHKRIH TGEKPYECED
210 220 230 240 250
CGKTFIGSSA LVIHQRVHTG EKPYECEECG KVFSHSSNLI KHQRTHTGEK
260 270 280 290 300
PYECDDCGKT FTQSCSLLEH HKIHTGEKPF QCNLCGKAFR RSSHLLRHQR
310 320 330 340 350
IHGDKAAPKL LHGETWEGQS RVASLGDIVE APETYQCNEC ERSFTRSRSL
360 370 380 390
IEHKKIHTGE KPYQCDACGK GFTRTSYLVQ HRRSHVGKKL SHSDL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07027815 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSRNOT00000084976; ENSRNOP00000073850; ENSRNOG00000051823 |
UCSCi | RGD:1309004, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07027815 Genomic DNA No translation available. |
3D structure databases
SMRi | D3ZCK0 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000024797 |
Proteomic databases
PaxDbi | D3ZCK0 |
Genome annotation databases
Ensembli | ENSRNOT00000084976; ENSRNOP00000073850; ENSRNOG00000051823 |
UCSCi | RGD:1309004, rat |
Organism-specific databases
RGDi | 1309004, Zkscan4 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000159644 |
HOGENOMi | CLU_002678_49_4_1 |
OMAi | GHCREDA |
Enzyme and pathway databases
Reactomei | R-RNO-212436, Generic Transcription Pathway |
Gene expression databases
Bgeei | ENSRNOG00000051823, Expressed in liver and 20 other tissues |
Family and domain databases
Gene3Di | 1.10.4020.10, 1 hit |
InterProi | View protein in InterPro IPR003309, SCAN_dom IPR038269, SCAN_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF02023, SCAN, 1 hit PF00096, zf-C2H2, 7 hits |
SMARTi | View protein in SMART SM00431, SCAN, 1 hit SM00355, ZnF_C2H2, 7 hits |
SUPFAMi | SSF57667, SSF57667, 4 hits |
PROSITEi | View protein in PROSITE PS50804, SCAN_BOX, 1 hit PS00028, ZINC_FINGER_C2H2_1, 7 hits PS50157, ZINC_FINGER_C2H2_2, 7 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | D3ZCK0_RAT | |
Accessioni | D3ZCK0Primary (citable) accession number: D3ZCK0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 3, 2013 | |
Last modified: | January 19, 2022 | |
This is version 93 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |