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Protein
Submitted name:

RCG32142, isoform CRA_b

Gene

Tp53rk

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • protein serine/threonine kinase activity Source: GO_Central

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-6804756 Regulation of TP53 Activity through Phosphorylation

Names & Taxonomyi

Protein namesi
Submitted name:
RCG32142, isoform CRA_bImported
Submitted name:
TP53-regulating kinaseImported
Gene namesi
Name:Tp53rkImported
ORF Names:rCG_32142Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1304911 Tp53rk

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiD3ZCD7

Expressioni

Gene expression databases

BgeeiENSRNOG00000007285 Expressed in 9 organ(s), highest expression level in testis

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000050360

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 244Protein kinaseInterPro annotationAdd BLAST221

Phylogenomic databases

eggNOGiKOG3087 Eukaryota
COG3642 LUCA
GeneTreeiENSGT00390000012914
KOiK08851
OMAiHKLYMEY
OrthoDBiEOG091G0LKE
TreeFamiTF325502

Family and domain databases

InterProiView protein in InterPro
IPR022495 Bud32
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR008266 Tyr_kinase_AS
PANTHERiPTHR12209 PTHR12209, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
TIGRFAMsiTIGR03724 arch_bud32, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00109 PROTEIN_KINASE_TYR, 1 hit

Sequencei

Sequence statusi: Complete.

D3ZCD7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGASSEAEA EALAAARERS RLFLSGLELV QQGAEARVFR GRFQGRAAVV
60 70 80 90 100
KHRFPKGYRH PELEARLGRR RTVQEARALL RCRRAGIAAP VVFFVDYASN
110 120 130 140 150
CLYMEEIEDS VTVRDYIQST METKQDPQCL LDLARKIGQV LARLHDEDLI
160 170 180 190 200
HGDLTTSNML LTRPLEQLHI VLIDFGLSFV SGLPEDKGVD LYVLEKAFLS
210 220 230 240
THPHTETVFE AFLKSYGASS KKSDPVLKKL DEVRLRGRKR SMVG
Length:244
Mass (Da):27,428
Last modified:April 20, 2010 - v1
Checksum:iC4726AA49C97DB78
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07054611 Genomic DNA No translation available.
CH474005 Genomic DNA Translation: EDL96432.1
RefSeqiNP_001102076.1, NM_001108606.1
UniGeneiRn.19574

Genome annotation databases

EnsembliENSRNOT00000049082; ENSRNOP00000050360; ENSRNOG00000007285
GeneIDi362272
KEGGirno:362272

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07054611 Genomic DNA No translation available.
CH474005 Genomic DNA Translation: EDL96432.1
RefSeqiNP_001102076.1, NM_001108606.1
UniGeneiRn.19574

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000050360

Proteomic databases

PRIDEiD3ZCD7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000049082; ENSRNOP00000050360; ENSRNOG00000007285
GeneIDi362272
KEGGirno:362272

Organism-specific databases

CTDi112858
RGDi1304911 Tp53rk

Phylogenomic databases

eggNOGiKOG3087 Eukaryota
COG3642 LUCA
GeneTreeiENSGT00390000012914
KOiK08851
OMAiHKLYMEY
OrthoDBiEOG091G0LKE
TreeFamiTF325502

Enzyme and pathway databases

ReactomeiR-RNO-6804756 Regulation of TP53 Activity through Phosphorylation

Gene expression databases

BgeeiENSRNOG00000007285 Expressed in 9 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR022495 Bud32
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR008266 Tyr_kinase_AS
PANTHERiPTHR12209 PTHR12209, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
TIGRFAMsiTIGR03724 arch_bud32, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00109 PROTEIN_KINASE_TYR, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3ZCD7_RAT
AccessioniPrimary (citable) accession number: D3ZCD7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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