Maff

Functionⁱ

GO - Molecular functionⁱ

DNA-binding transcription factor activity Source: InterPro
sequence-specific DNA binding Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

in utero embryonic development Source: Ensembl
positive regulation of transcription by RNA polymerase II Source: Ensembl
regulation of epidermal cell differentiation Source: Ensembl
skeletal muscle cell differentiation Source: Ensembl
transcription, DNA-templated Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-bindingSAAS annotation
Biological process	Transcription, Transcription regulationSAAS annotation

Enzyme and pathway databases

Reactomeⁱ	R-RNO-983231 Factors involved in megakaryocyte development and platelet production

Reactomeⁱ

R-RNO-983231 Factors involved in megakaryocyte development and platelet production

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: MAF bZIP transcription factor FImported Submitted name: V-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (Avian) (Predicted)Imported
Gene namesⁱ	Name:MaffImported Synonyms:Maff_predictedImported ORF Names:rCG_60141Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 7

Organism-specific databases

Rat genome database More...RGDⁱ	1309531 Maff

RGDⁱ

1309531 Maff

Subcellular locationⁱ

GO - Cellular component

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000012886 Expressed in 9 organ(s), highest expression level in heart

Bgeeⁱ

ENSRNOG00000012886 Expressed in 9 organ(s), highest expression level in heart

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000017181

STRINGⁱ

10116.ENSRNOP00000017181

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	51 – 114	BZIPInterPro annotationAdd BLAST		64

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	69 – 110	Sequence analysisAdd BLAST		42

Sequence similaritiesⁱ

Belongs to the bZIP family.SAAS annotation

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG4196 Eukaryota ENOG41102C7 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074549
KEGG Orthology (KO) More...KOⁱ	K09037
OMAⁱ	NRQLKLR
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0H46
TreeFamⁱ	TF325689

Family and domain databases

InterProⁱ	View protein in InterPro IPR004827 bZIP IPR004826 bZIP_Maf IPR033531 MafF IPR008917 TF_DNA-bd_sf IPR024874 Transciption_factor_Maf_fam
PANTHERⁱ	PTHR10129 PTHR10129, 1 hit PTHR10129:SF25 PTHR10129:SF25, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03131 bZIP_Maf, 1 hit
SMARTⁱ	View protein in SMART SM00338 BRLZ, 1 hit
SUPFAMⁱ	SSF47454 SSF47454, 1 hit
PROSITEⁱ	View protein in PROSITE PS50217 BZIP, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

D3ZC87-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSVDPLSSKA LKVKRELSEN TPHLSDEALM GLSVRELNRN LRGLSAEEVT 
        60         70         80         90        100
RLKQRRRTLK NRGYAASCRV KRVCQKEELQ KQKSELEREV DKLARENAAM 
       110        120        130        140        150
RLELDALRGK CEALQGFARS VAAARGPAAL VAPASVITIV KSVPGPSPAP 

DPAPCS

Length:156

Mass (Da):17,041

Last modified:April 20, 2010 - v1

Checksum:ⁱ4EBC9EF226D23387

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07058504 Genomic DNA No translation available. CH473950 Genomic DNA Translation: EDM15807.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001124045.1, NM_001130573.1
UniGeneⁱ	Rn.31639

Genome annotation databases

Ensemblⁱ	ENSRNOT00000017181; ENSRNOP00000017181; ENSRNOG00000012886
GeneIDⁱ	366960
KEGGⁱ	rno:366960
UCSC genome browser More...UCSCⁱ	RGD:1309531 rat

Similar proteinsⁱ

50% Identity

Protein	Similar proteins		Species	Score	Length	Source
D3ZC87	Uncharacterized protein		HORSE		97	UniRef50_D3ZC87
transcription factor MafF isoform X1		DELLE		293
Transcription factor MafF (Fragment)		HUMAN		125
MAFF isoform 5 (Fragment)		PONAB		93
Uncharacterized protein (Fragment)		AILME		115
+13

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07058504 Genomic DNA No translation available. CH473950 Genomic DNA Translation: EDM15807.1
RefSeqⁱ	NP_001124045.1, NM_001130573.1
UniGeneⁱ	Rn.31639

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000017181

STRINGⁱ

10116.ENSRNOP00000017181

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000017181; ENSRNOP00000017181; ENSRNOG00000012886
GeneIDⁱ	366960
KEGGⁱ	rno:366960
UCSCⁱ	RGD:1309531 rat

Organism-specific databases

CTDⁱ	23764
RGDⁱ	1309531 Maff

Phylogenomic databases

eggNOGⁱ	KOG4196 Eukaryota ENOG41102C7 LUCA
GeneTreeⁱ	ENSGT00550000074549
KOⁱ	K09037
OMAⁱ	NRQLKLR
OrthoDBⁱ	EOG091G0H46
TreeFamⁱ	TF325689

Enzyme and pathway databases

Reactomeⁱ	R-RNO-983231 Factors involved in megakaryocyte development and platelet production

Reactomeⁱ

R-RNO-983231 Factors involved in megakaryocyte development and platelet production

Gene expression databases

Bgeeⁱ	ENSRNOG00000012886 Expressed in 9 organ(s), highest expression level in heart

Bgeeⁱ

ENSRNOG00000012886 Expressed in 9 organ(s), highest expression level in heart

Family and domain databases

InterProⁱ	View protein in InterPro IPR004827 bZIP IPR004826 bZIP_Maf IPR033531 MafF IPR008917 TF_DNA-bd_sf IPR024874 Transciption_factor_Maf_fam
PANTHERⁱ	PTHR10129 PTHR10129, 1 hit PTHR10129:SF25 PTHR10129:SF25, 1 hit
Pfamⁱ	View protein in Pfam PF03131 bZIP_Maf, 1 hit
SMARTⁱ	View protein in SMART SM00338 BRLZ, 1 hit
SUPFAMⁱ	SSF47454 SSF47454, 1 hit
PROSITEⁱ	View protein in PROSITE PS50217 BZIP, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	D3ZC87_RAT
Accessionⁱ	D3ZC87Primary (citable) accession number: D3ZC87
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 20, 2010
	Last sequence update:	April 20, 2010
	Last modified:	September 12, 2018
	This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - D3ZC87 (D3ZC87_RAT)

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MAF bZIP transcription factor F

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Mitochondrion

Nucleus

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ