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UniProtKB - D3ZC87 (D3ZC87_RAT)
Protein
Submitted name:
MAF bZIP transcription factor F
Gene
Maff
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: RGD
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific DNA binding Source: RGD
- sequence-specific double-stranded DNA binding Source: RGD
GO - Biological processi
- in utero embryonic development Source: RGD
- positive regulation of transcription by RNA polymerase II Source: RGD
- regulation of epidermal cell differentiation Source: RGD
- regulation of transcription by RNA polymerase II Source: GO_Central
- skeletal muscle cell differentiation Source: RGD
Keywordsi
Molecular function | DNA-bindingARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Enzyme and pathway databases
Reactomei | R-RNO-983231, Factors involved in megakaryocyte development and platelet production |
Names & Taxonomyi
Protein namesi | Submitted name: MAF bZIP transcription factor FSubmitted name: V-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (Avian) (Predicted)Imported |
Gene namesi | ORF Names:rCG_60141Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1309531, Maff |
Subcellular locationi
Nucleus
- nucleus Source: GO_Central
- RNA polymerase II transcription regulator complex Source: RGD
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSRNOG00000012886, Expressed in testis and 21 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 51 – 114 | BZIPInterPro annotationAdd BLAST | 64 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 69 – 110 | Sequence analysisAdd BLAST | 42 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG4196, Eukaryota |
GeneTreei | ENSGT00940000161112 |
HOGENOMi | CLU_112948_0_1_1 |
OMAi | MGENTPH |
OrthoDBi | 1395389at2759 |
TreeFami | TF325689 |
Family and domain databases
InterProi | View protein in InterPro IPR004827, bZIP IPR004826, bZIP_Maf IPR046347, bZIP_sf IPR033531, MafF IPR008917, TF_DNA-bd_sf IPR024874, Transcription_factor_Maf_fam |
PANTHERi | PTHR10129, PTHR10129, 1 hit PTHR10129:SF25, PTHR10129:SF25, 1 hit |
Pfami | View protein in Pfam PF03131, bZIP_Maf, 1 hit |
SMARTi | View protein in SMART SM00338, BRLZ, 1 hit |
SUPFAMi | SSF47454, SSF47454, 1 hit SSF57959, SSF57959, 1 hit |
PROSITEi | View protein in PROSITE PS50217, BZIP, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
D3ZC87-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSVDPLSSKA LKVKRELSEN TPHLSDEALM GLSVRELNRN LRGLSAEEVT
60 70 80 90 100
RLKQRRRTLK NRGYAASCRV KRVCQKEELQ KQKSELEREV DKLARENAAM
110 120 130 140 150
RLELDALRGK CEALQGFARS VAAARGPAAL VAPASVITIV KSVPGPSPAP
DPAPCS
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A8I5ZUD9 | A0A8I5ZUD9_RAT | MAF bZIP transcription factor F | Maff | 168 | Annotation score: | ||
A0A8I6AW56 | A0A8I6AW56_RAT | MAF bZIP transcription factor F | Maff | 184 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473950 Genomic DNA Translation: EDM15807.1 |
RefSeqi | NP_001124045.1, NM_001130573.1 |
Genome annotation databases
Ensembli | ENSRNOT00000017181.5; ENSRNOP00000017181.4; ENSRNOG00000012886.5 |
GeneIDi | 366960 |
KEGGi | rno:366960 |
UCSCi | RGD:1309531, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473950 Genomic DNA Translation: EDM15807.1 |
RefSeqi | NP_001124045.1, NM_001130573.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000017181 |
Genome annotation databases
Ensembli | ENSRNOT00000017181.5; ENSRNOP00000017181.4; ENSRNOG00000012886.5 |
GeneIDi | 366960 |
KEGGi | rno:366960 |
UCSCi | RGD:1309531, rat |
Organism-specific databases
CTDi | 23764 |
RGDi | 1309531, Maff |
Phylogenomic databases
eggNOGi | KOG4196, Eukaryota |
GeneTreei | ENSGT00940000161112 |
HOGENOMi | CLU_112948_0_1_1 |
OMAi | MGENTPH |
OrthoDBi | 1395389at2759 |
TreeFami | TF325689 |
Enzyme and pathway databases
Reactomei | R-RNO-983231, Factors involved in megakaryocyte development and platelet production |
Gene expression databases
Bgeei | ENSRNOG00000012886, Expressed in testis and 21 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR004827, bZIP IPR004826, bZIP_Maf IPR046347, bZIP_sf IPR033531, MafF IPR008917, TF_DNA-bd_sf IPR024874, Transcription_factor_Maf_fam |
PANTHERi | PTHR10129, PTHR10129, 1 hit PTHR10129:SF25, PTHR10129:SF25, 1 hit |
Pfami | View protein in Pfam PF03131, bZIP_Maf, 1 hit |
SMARTi | View protein in SMART SM00338, BRLZ, 1 hit |
SUPFAMi | SSF47454, SSF47454, 1 hit SSF57959, SSF57959, 1 hit |
PROSITEi | View protein in PROSITE PS50217, BZIP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | D3ZC87_RAT | |
Accessioni | D3ZC87Primary (citable) accession number: D3ZC87 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 20, 2010 | |
Last modified: | May 25, 2022 | |
This is version 96 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |