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Entry version 63 (16 Jan 2019)
Sequence version 1 (20 Apr 2010)
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Protein

Cartilage intermediate layer protein 2

Gene

Cilp2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in cartilage scaffolding.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cartilage intermediate layer protein 2Imported
Cleaved into the following 2 chains:
Cartilage intermediate layer protein 2 C1By similarity
Cartilage intermediate layer protein 2 C2By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cilp2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1915959 Cilp2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Extracellular matrix, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 20Sequence analysisAdd BLAST20
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500305286521 – 1162Cartilage intermediate layer protein 2Sequence analysisAdd BLAST1142
ChainiPRO_000043717522 – ?715Cartilage intermediate layer protein 2 C1By similarityAdd BLAST694
ChainiPRO_0000437176?716 – 1162Cartilage intermediate layer protein 2 C2By similarityAdd BLAST447

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi158 ↔ 191PROSITE-ProRule annotation
Disulfide bondi162 ↔ 196PROSITE-ProRule annotation
Disulfide bondi173 ↔ 181PROSITE-ProRule annotation
Disulfide bondi314 ↔ 360PROSITE-ProRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi330N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

May be cleaved into 2 chains possibly by a furin-like protease upon or preceding secretion.1 Publication
N-glycosylated.1 Publication

Keywords - PTMi

Cleavage on pair of basic residues, Disulfide bond, Glycoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
D3Z7H8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
D3Z7H8

PRoteomics IDEntifications database

More...
PRIDEi
D3Z7H8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
D3Z7H8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
D3Z7H8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in articulated and meniscal cartilage (at protein level). Also detected in heart, skeletal muscle and brain. Not detected in growth plate cartilage.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

In the knee joint, detected in articular cartilage from 2 weeks of age but not at earlier stages (at protein level). Initially localizes to the surface zone of articular cartilage but by maturity (8 weeks) is found in the intermediate to deep zones (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000044006 Expressed in 113 organ(s), highest expression level in cardiac ventricle

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
D3Z7H8 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000061544

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
D3Z7H8

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
D3Z7H8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini146 – 197TSP type-1PROSITE-ProRule annotationAdd BLAST52
Domaini293 – 377Ig-like C2-typePROSITE-ProRule annotationAdd BLAST85

Keywords - Domaini

Immunoglobulin domain, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJBD Eukaryota
ENOG410XXZR LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000008152

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000111676

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
D3Z7H8

Identification of Orthologs from Complete Genome Data

More...
OMAi
GVWEEES

Database of Orthologous Groups

More...
OrthoDBi
629181at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
D3Z7H8

TreeFam database of animal gene trees

More...
TreeFami
TF330132

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.20.100.10, 1 hit
2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013784 Carb-bd-like_fold
IPR039675 CILP1/CILP2
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR000884 TSP1_rpt
IPR036383 TSP1_rpt_sf
IPR025155 WxxW_domain

The PANTHER Classification System

More...
PANTHERi
PTHR15031 PTHR15031, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13330 Mucin2_WxxW, 1 hit
PF00090 TSP_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00409 IG, 1 hit
SM00408 IGc2, 1 hit
SM00209 TSP1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726 SSF48726, 1 hit
SSF49452 SSF49452, 1 hit
SSF82895 SSF82895, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS50092 TSP1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

D3Z7H8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASPLPLLYL CLAALHLAGA RDATPTEEHT STARGLQGRP PDTGQPSPAL
60 70 80 90 100
EDWEEASEWT SWFNVDHPGG DGDFESLAAI RFYYGPARVC PRPLALEART
110 120 130 140 150
TDWALPAAMG ERVHANPERG FWCLNREQPR GRRCSNYHVR FRCPLEAAWG
160 170 180 190 200
AWGAWGLCSK SCGLGRRLRR RSCQSSSGDT CPGSPQEAQK CVRSRCPGCS
210 220 230 240 250
SDTCGCPNHI LLGSVVTPSG RPLSGARVSL RTRPGTIATS GTHGTFQVPG
260 270 280 290 300
VCAGSKASVS AQMNGFSAGT AQAHANSSNT ATVTIILEEL GKPYLVKHPE
310 320 330 340 350
SRVREAGQNV TFCCKASGTP MPKKYSWFHN GTLLDRRQQG SGPHLELQGL
360 370 380 390 400
HQAQAGEYHC KAWNEAGTVR SRAALLTILA PGQQACDPRP QEHLIKLPDD
410 420 430 440 450
CGQPGGGPTY LDVGLCADTR CPGPVGSGPR CGDAGSRCCS VLRLESRDIR
460 470 480 490 500
CSGYVLPVKV VAECGCRKCL PRRGLVRGRV VAADSGEPLR FARILLGRAP
510 520 530 540 550
IGFTSYQGDF TIEVPPATER LVVTFVDPSG DFVDSVRVLP FDPRGAGVYH
560 570 580 590 600
EIRALRKAAA VLLDAERGGE IPLGSTEEAP ALGELVLPPG TFHHPDGRPY
610 620 630 640 650
TGPVEARVTF VDPRDLASAS AASSDLRFLD SAGELAPLRT YGMFAVDLRA
660 670 680 690 700
PGSTEQLHVA RADVHVDADH VRMPGHAEAL ALWSLDPETG LWEEEGSEQG
710 720 730 740 750
SGGFRRETAA ARVRREERAF LVGALTMRER RLFNLDVPER RRCFVKVRAY
760 770 780 790 800
GTDRFAPAEQ VQGVVVTLLN LEPAPGFTAN PRAWGRFDSA VTGPNGACVP
810 820 830 840 850
AFCDAEKPDA YTAFVTAALG GEELEAAPSR PRATAAVVGV AQPYLERLGY
860 870 880 890 900
QRTDHDDPAL KRTGFRLNLA RPRAGHESEA HGPVYPWRRL RDCEDAPVTD
910 920 930 940 950
SHFRFSRVEA DKYEYDVVPF HEGAPASWTG DLLAWWPNPQ EFRACFLKVR
960 970 980 990 1000
LQGPQEYMVR SHNAGGTHEA TRGRLYGLRD TRSVRHPERP GASAACVEFK
1010 1020 1030 1040 1050
CGGMLFDQRQ VDRTLVTVTP QGSCRRVAVN TLLQDYLARH PPLAAADDPA
1060 1070 1080 1090 1100
AFAMLAPLDA LGHNYGVYTV TDQSPRLAKE IAIGRCFDGS SDGFSREMKA
1110 1120 1130 1140 1150
DAGTAVTFQC REPPARPSLF QRLLENPSSA LGDIRREMGQ ATRYSRVNQT
1160
QAGDTGPFGP GQ
Length:1,162
Mass (Da):125,934
Last modified:April 20, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i96C290391AB60A37
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC158564 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS40363.1

NCBI Reference Sequences

More...
RefSeqi
NP_081094.2, NM_026818.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.334584

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000057831; ENSMUSP00000061544; ENSMUSG00000044006

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
68709

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:68709

UCSC genome browser

More...
UCSCi
uc009lyb.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC158564 Genomic DNA No translation available.
CCDSiCCDS40363.1
RefSeqiNP_081094.2, NM_026818.2
UniGeneiMm.334584

3D structure databases

ProteinModelPortaliD3Z7H8
SMRiD3Z7H8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000061544

PTM databases

iPTMnetiD3Z7H8
PhosphoSitePlusiD3Z7H8

Proteomic databases

MaxQBiD3Z7H8
PaxDbiD3Z7H8
PRIDEiD3Z7H8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000057831; ENSMUSP00000061544; ENSMUSG00000044006
GeneIDi68709
KEGGimmu:68709
UCSCiuc009lyb.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
148113
MGIiMGI:1915959 Cilp2

Phylogenomic databases

eggNOGiENOG410IJBD Eukaryota
ENOG410XXZR LUCA
GeneTreeiENSGT00390000008152
HOGENOMiHOG000111676
InParanoidiD3Z7H8
OMAiGVWEEES
OrthoDBi629181at2759
PhylomeDBiD3Z7H8
TreeFamiTF330132

Miscellaneous databases

Protein Ontology

More...
PROi
PR:D3Z7H8

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000044006 Expressed in 113 organ(s), highest expression level in cardiac ventricle
GenevisibleiD3Z7H8 MM

Family and domain databases

Gene3Di2.20.100.10, 1 hit
2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR013784 Carb-bd-like_fold
IPR039675 CILP1/CILP2
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR000884 TSP1_rpt
IPR036383 TSP1_rpt_sf
IPR025155 WxxW_domain
PANTHERiPTHR15031 PTHR15031, 1 hit
PfamiView protein in Pfam
PF13330 Mucin2_WxxW, 1 hit
PF00090 TSP_1, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00408 IGc2, 1 hit
SM00209 TSP1, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF49452 SSF49452, 1 hit
SSF82895 SSF82895, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS50092 TSP1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCILP2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D3Z7H8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 7, 2016
Last sequence update: April 20, 2010
Last modified: January 16, 2019
This is version 63 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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