UniProtKB - D3Z6P9 (D3Z6P9_MOUSE)
Protein
Submitted name:
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
Gene
Ddx43
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- helicase activity Source: UniProtKB-KW
- RNA binding Source: InterPro
Keywordsi
Molecular function | HelicaseUniRule annotation, Hydrolase |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 43Imported |
Gene namesi | Name:Ddx43Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:3642857 Ddx43 |
PTM / Processingi
Proteomic databases
PaxDbi | D3Z6P9 |
PRIDEi | D3Z6P9 |
PTM databases
iPTMneti | D3Z6P9 |
PhosphoSitePlusi | D3Z6P9 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000070291 Expressed in 58 organ(s), highest expression level in testis |
Genevisiblei | D3Z6P9 MM |
Structurei
3D structure databases
ProteinModelPortali | D3Z6P9 |
SMRi | D3Z6P9 |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 240 – 268 | Q_MOTIFInterPro annotationAdd BLAST | 29 | |
Domaini | 271 – 446 | Helicase ATP-bindingInterPro annotationAdd BLAST | 176 | |
Domaini | 458 – 623 | Helicase C-terminalInterPro annotationAdd BLAST | 166 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 240 – 268 | Q motifPROSITE-ProRule annotationAdd BLAST | 29 |
Sequence similaritiesi
Belongs to the DEAD box helicase family.UniRule annotation
Phylogenomic databases
eggNOGi | KOG0336 Eukaryota ENOG410XR3V LUCA |
GeneTreei | ENSGT00940000163229 |
HOGENOMi | HOG000268804 |
InParanoidi | D3Z6P9 |
KOi | K17043 |
OMAi | VLMAERY |
OrthoDBi | 471730at2759 |
PhylomeDBi | D3Z6P9 |
TreeFami | TF312949 |
Family and domain databases
CDDi | cd00079 HELICc, 1 hit |
Gene3Di | 3.30.1370.10, 1 hit |
InterProi | View protein in InterPro IPR011545 DEAD/DEAH_box_helicase_dom IPR014001 Helicase_ATP-bd IPR001650 Helicase_C IPR004087 KH_dom IPR004088 KH_dom_type_1 IPR036612 KH_dom_type_1_sf IPR027417 P-loop_NTPase IPR000629 RNA-helicase_DEAD-box_CS IPR014014 RNA_helicase_DEAD_Q_motif |
Pfami | View protein in Pfam PF00270 DEAD, 1 hit PF00271 Helicase_C, 1 hit PF00013 KH_1, 1 hit |
SMARTi | View protein in SMART SM00487 DEXDc, 1 hit SM00490 HELICc, 1 hit SM00322 KH, 1 hit |
SUPFAMi | SSF52540 SSF52540, 1 hit SSF54791 SSF54791, 1 hit |
PROSITEi | View protein in PROSITE PS00039 DEAD_ATP_HELICASE, 1 hit PS51192 HELICASE_ATP_BIND_1, 1 hit PS51194 HELICASE_CTER, 1 hit PS51195 Q_MOTIF, 1 hit |
i Sequence
Sequence statusi: Complete.
D3Z6P9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSRREPAANA SSSGVAPRRS STGSRGADRT ATEETNRRGR VGSRGAGGGW
60 70 80 90 100
REPAGAAEAT AAGRREPPLC FGVKNDVVGA VIGRGGSKIR EIQNTTNTRI
110 120 130 140 150
QVIKGNPEAE IKIFGNKAMQ TKAKTVIDNV VKKQQNYIPG QRVGIIAFQP
160 170 180 190 200
TVGADTSTSE SVTDDQPLID WDQIREDALK WEKKKWADLP PIKKNFYIES
210 220 230 240 250
ATTSSMSQVQ IDNWRKENFN ITCDDLKDGE KRPIPNPICK FEDAFQSYPE
260 270 280 290 300
VMENIKRAGF QKPTPIQSQA WPIVLQGIDL IGVAQTGTGK TLSYLMPGFI
310 320 330 340 350
HLDSQPLARE QRNGPGMLVL TPTRELALQV EAECSKYSYG DLKSVCVYGG
360 370 380 390 400
GDRDGQIQDV SKGVDIIIAT PGRLNDLQMN NFVNLKSVTY LVLDEADKML
410 420 430 440 450
DMGFEPQIMK ILLDVRPDRQ TIMTSATWPY AVRRLAQSYL KEPMIVYVGT
460 470 480 490 500
LDLVAVSTVK QNIIITTEEE KRTHIQTFLE NMSPKDKVIV FVSRKAVADH
510 520 530 540 550
LSSDLILRHI SVESLHGNRE QSDREKALEN FKTGKVRILI ATDLASRGLD
560 570 580 590 600
VHDITHVYNY DFPRNIEEYV HRVGRTGRAG RTGMSITLIT RNDWRVATEL
610 620 630 640
INILERANQN IPEELVLMAE RYKANKLKRE MEKKMGRPQG KPQKFY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC138587 Genomic DNA No translation available. AC158987 Genomic DNA No translation available. |
RefSeqi | NP_001177973.1, NM_001191044.1 |
UniGenei | Mm.158166 |
Genome annotation databases
Ensembli | ENSMUST00000113367; ENSMUSP00000108994; ENSMUSG00000070291 |
GeneIDi | 100048658 |
KEGGi | mmu:100048658 |
UCSCi | uc012gxe.1 mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC138587 Genomic DNA No translation available. AC158987 Genomic DNA No translation available. |
RefSeqi | NP_001177973.1, NM_001191044.1 |
UniGenei | Mm.158166 |
3D structure databases
ProteinModelPortali | D3Z6P9 |
SMRi | D3Z6P9 |
ModBasei | Search... |
MobiDBi | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000108994 |
PTM databases
iPTMneti | D3Z6P9 |
PhosphoSitePlusi | D3Z6P9 |
Proteomic databases
PaxDbi | D3Z6P9 |
PRIDEi | D3Z6P9 |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Genome annotation databases
Ensembli | ENSMUST00000113367; ENSMUSP00000108994; ENSMUSG00000070291 |
GeneIDi | 100048658 |
KEGGi | mmu:100048658 |
UCSCi | uc012gxe.1 mouse |
Organism-specific databases
CTDi | 55510 |
MGIi | MGI:3642857 Ddx43 |
Phylogenomic databases
eggNOGi | KOG0336 Eukaryota ENOG410XR3V LUCA |
GeneTreei | ENSGT00940000163229 |
HOGENOMi | HOG000268804 |
InParanoidi | D3Z6P9 |
KOi | K17043 |
OMAi | VLMAERY |
OrthoDBi | 471730at2759 |
PhylomeDBi | D3Z6P9 |
TreeFami | TF312949 |
Miscellaneous databases
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000070291 Expressed in 58 organ(s), highest expression level in testis |
Genevisiblei | D3Z6P9 MM |
Family and domain databases
CDDi | cd00079 HELICc, 1 hit |
Gene3Di | 3.30.1370.10, 1 hit |
InterProi | View protein in InterPro IPR011545 DEAD/DEAH_box_helicase_dom IPR014001 Helicase_ATP-bd IPR001650 Helicase_C IPR004087 KH_dom IPR004088 KH_dom_type_1 IPR036612 KH_dom_type_1_sf IPR027417 P-loop_NTPase IPR000629 RNA-helicase_DEAD-box_CS IPR014014 RNA_helicase_DEAD_Q_motif |
Pfami | View protein in Pfam PF00270 DEAD, 1 hit PF00271 Helicase_C, 1 hit PF00013 KH_1, 1 hit |
SMARTi | View protein in SMART SM00487 DEXDc, 1 hit SM00490 HELICc, 1 hit SM00322 KH, 1 hit |
SUPFAMi | SSF52540 SSF52540, 1 hit SSF54791 SSF54791, 1 hit |
PROSITEi | View protein in PROSITE PS00039 DEAD_ATP_HELICASE, 1 hit PS51192 HELICASE_ATP_BIND_1, 1 hit PS51194 HELICASE_CTER, 1 hit PS51195 Q_MOTIF, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | D3Z6P9_MOUSE | |
Accessioni | D3Z6P9Primary (citable) accession number: D3Z6P9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 20, 2010 | |
Last modified: | January 16, 2019 | |
This is version 75 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |