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Protein
Submitted name:

Kinetochore-associated protein NSL1 homolog

Gene

Nsl1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-MMU-2467813 Separation of Sister Chromatids
R-MMU-2500257 Resolution of Sister Chromatid Cohesion
R-MMU-5663220 RHO GTPases Activate Formins
R-MMU-68877 Mitotic Prometaphase

Names & Taxonomyi

Protein namesi
Submitted name:
Kinetochore-associated protein NSL1 homologImported
Gene namesi
Name:Nsl1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:2685830 Nsl1

Subcellular locationi

PTM / Processingi

Proteomic databases

PeptideAtlasiD3Z4S2
PRIDEiD3Z4S2

Expressioni

Gene expression databases

BgeeiENSMUSG00000062510 Expressed in 108 organ(s), highest expression level in humerus cartilage element
ExpressionAtlasiD3Z4S2 baseline and differential

Structurei

3D structure databases

SMRiD3Z4S2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili108 – 128Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IXS8 Eukaryota
ENOG41125EG LUCA
GeneTreeiENSGT00390000001374
HOGENOMiHOG000113863

Family and domain databases

InterProiView protein in InterPro
IPR013950 Mis14/Nsl1
PANTHERiPTHR31749 PTHR31749, 1 hit
PfamiView protein in Pfam
PF08641 Mis14, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

D3Z4S2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAVSETVLV SAPQDHDAQA ASDPQATAAD SPLEDFRVRC TLKRAVMEVM
60 70 80 90 100
EMCGRFVQEL GAVLPEDVRE LALRDAQWTF ESAVQENVSF NGQAWEEAKE
110 120 130 140 150
HGLMDSDIKV LEDEFDELIV DVATKRRQYP RRILESVIKT LKAQHASLKQ
160 170 180 190
YHPVVHPLDL KCDPDPGTQC VISGRVIFSE LHWILEEVNS DSI
Length:193
Mass (Da):21,685
Last modified:October 5, 2016 - v8
Checksum:i03D6E5A79D0882C3
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8K305NSL1_MOUSE
Kinetochore-associated protein NSL1...
Nsl1
281Annotation score:
E9QME3E9QME3_MOUSE
Kinetochore-associated protein NSL1...
Nsl1
281Annotation score:
E9Q3W6E9Q3W6_MOUSE
Kinetochore-associated protein NSL1...
Nsl1
174Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei193Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC138229 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000076952; ENSMUSP00000076220; ENSMUSG00000062510

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC138229 Genomic DNA No translation available.

3D structure databases

SMRiD3Z4S2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiD3Z4S2
PRIDEiD3Z4S2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000076952; ENSMUSP00000076220; ENSMUSG00000062510

Organism-specific databases

MGIiMGI:2685830 Nsl1

Phylogenomic databases

eggNOGiENOG410IXS8 Eukaryota
ENOG41125EG LUCA
GeneTreeiENSGT00390000001374
HOGENOMiHOG000113863

Enzyme and pathway databases

ReactomeiR-MMU-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-MMU-2467813 Separation of Sister Chromatids
R-MMU-2500257 Resolution of Sister Chromatid Cohesion
R-MMU-5663220 RHO GTPases Activate Formins
R-MMU-68877 Mitotic Prometaphase

Miscellaneous databases

ChiTaRSiNsl1 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000062510 Expressed in 108 organ(s), highest expression level in humerus cartilage element
ExpressionAtlasiD3Z4S2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR013950 Mis14/Nsl1
PANTHERiPTHR31749 PTHR31749, 1 hit
PfamiView protein in Pfam
PF08641 Mis14, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3Z4S2_MOUSE
AccessioniPrimary (citable) accession number: D3Z4S2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 58 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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