Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 72 (08 May 2019)
Sequence version 1 (20 Apr 2010)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Phosphatidylinositol glycan anchor biosynthesis, class G

Gene

Pigg

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Phosphatidylinositol glycan anchor biosynthesis, class GImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PiggImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3576484 Pigg

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei7 – 28HelicalSequence analysisAdd BLAST22
Transmembranei432 – 450HelicalSequence analysisAdd BLAST19
Transmembranei462 – 482HelicalSequence analysisAdd BLAST21
Transmembranei494 – 523HelicalSequence analysisAdd BLAST30
Transmembranei544 – 563HelicalSequence analysisAdd BLAST20
Transmembranei688 – 705HelicalSequence analysisAdd BLAST18
Transmembranei717 – 738HelicalSequence analysisAdd BLAST22
Transmembranei744 – 764HelicalSequence analysisAdd BLAST21
Transmembranei785 – 802HelicalSequence analysisAdd BLAST18
Transmembranei878 – 900HelicalSequence analysisAdd BLAST23
Transmembranei912 – 935HelicalSequence analysisAdd BLAST24
Transmembranei947 – 966HelicalSequence analysisAdd BLAST20

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
D3Z4I0

MaxQB - The MaxQuant DataBase

More...
MaxQBi
D3Z4I0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
D3Z4I0

PRoteomics IDEntifications database

More...
PRIDEi
D3Z4I0

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
D3Z4I0

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
D3Z4I0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000029263 Expressed in 216 organ(s), highest expression level in adult mammalian kidney

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
D3Z4I0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
D3Z4I0 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000031189

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2125 Eukaryota
COG1524 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00910000144269

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000068020

KEGG Orthology (KO)

More...
KOi
K05310

Database of Orthologous Groups

More...
OrthoDBi
848878at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
D3Z4I0

TreeFam database of animal gene trees

More...
TreeFami
TF300609

Family and domain databases

Conserved Domains Database

More...
CDDi
cd16024 GPI_EPT_2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.720.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017850 Alkaline_phosphatase_core_sf
IPR002591 Phosphodiest/P_Trfase
IPR037674 PIG-G_N
IPR039527 PIGG/GPI7

The PANTHER Classification System

More...
PANTHERi
PTHR23072 PTHR23072, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01663 Phosphodiest, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53649 SSF53649, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

D3Z4I0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRLGSGAFAA SCVAIEVIGV AIFIRGFFPA PVRSSARPEH DAETPAPEPV
60 70 80 90 100
AGVRSNWTKL PPPLFSKVVI VLIDALRDDF VFGSKGVKYM PYTTYLVEKG
110 120 130 140 150
ASHSFVAEAK PPTVTMPRIK ALMTGSLPGF VDVIRNLNSP VLLEDNVLRQ
160 170 180 190 200
AKAAGKRIIF YGDETWVKLF PKHFVEYDGT TSFFVSDYIE VDKNVTRHLD
210 220 230 240 250
KVLKRGDWDV LILHYLGLDH IGHISGPNSP LIGHKLSEMD SVLMKIHTSL
260 270 280 290 300
LSKDRETLLP SLLVLCGDHG MSETGSHGAS STEEVSTPLL LISSAFERKP
310 320 330 340 350
GDIRHPKHVQ QTDLAATLAI GLGLPIPKDS VGSLLFPVIE GKPMREQLRF
360 370 380 390 400
LHLNTLQLSK LLQENVPSYE KDPGFEQFKM AEKLHGNWVK LHLEENHSDI
410 420 430 440 450
LLGLGTKVLR HYLGALKTLS LSLSTQVAQY DMYSMAVLAL FLLSTPHVLC
460 470 480 490 500
RKAELDVPLL SPVFSLLFYL VFLVLSAIHV LVCTSSESSC YLCSLSWLAV
510 520 530 540 550
GAVMLLVSAL FCAILSALIR MVIDSTLLKK NAADASSGWS EVNLLLLLGT
560 570 580 590 600
VGHVLSLGAS SFVEEEHQTW YFLINTLCLA LSQETCRSYF LGDECEPQRH
610 620 630 640 650
SHVEQQCVNL LACPLQDSTS YNTPESGTAG KRVSLLEAQG SCKWWTVLAS
660 670 680 690 700
PWLVLLCCRL LRSLNQTGVQ GAHRPDFSHW LTSSDHKVQL SGLAALSLVV
710 720 730 740 750
IFMLVQRRCS LVSKVALALG LLGVFCYRAA IGIVQFPWQS DNKGISKGII
760 770 780 790 800
EARFVYVFVL GILFTGTKDL LKAQVIATDF KTKTVGLWEM HSGLVLLAAL
810 820 830 840 850
LLRPHNLPVL AFSLLIQTVM TKFIWKPLRH DAAEITVMHY WFGQAFFYFQ
860 870 880 890 900
GNSNNIATID ISAGFVGLDT YMEVPATFLT VFGTYVGPVL WASHLVYFLS
910 920 930 940 950
SEGNNSALSR SCFCYALICS VPVATYIVLV TSLRYHLFIW SVFSPKLLYE
960 970
GMHLLITAAI CAVFTATNQT RHRRA
Length:975
Mass (Da):107,688
Last modified:April 20, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i751D896FDED0F6EA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3Z3Y1D3Z3Y1_MOUSE
Phosphatidylinositol glycan anchor ...
Pigg
983Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YTQ6D3YTQ6_MOUSE
Phosphatidylinositol glycan anchor ...
Pigg
850Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC124107 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001074703.1, NM_001081234.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000031189; ENSMUSP00000031189; ENSMUSG00000029263

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
433931

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:433931

UCSC genome browser

More...
UCSCi
uc008ynu.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124107 Genomic DNA No translation available.
RefSeqiNP_001074703.1, NM_001081234.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031189

PTM databases

PhosphoSitePlusiD3Z4I0
SwissPalmiD3Z4I0

Proteomic databases

EPDiD3Z4I0
MaxQBiD3Z4I0
PaxDbiD3Z4I0
PRIDEiD3Z4I0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000031189; ENSMUSP00000031189; ENSMUSG00000029263
GeneIDi433931
KEGGimmu:433931
UCSCiuc008ynu.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54872
MGIiMGI:3576484 Pigg

Phylogenomic databases

eggNOGiKOG2125 Eukaryota
COG1524 LUCA
GeneTreeiENSGT00910000144269
HOGENOMiHOG000068020
KOiK05310
OrthoDBi848878at2759
PhylomeDBiD3Z4I0
TreeFamiTF300609

Miscellaneous databases

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000029263 Expressed in 216 organ(s), highest expression level in adult mammalian kidney
ExpressionAtlasiD3Z4I0 baseline and differential
GenevisibleiD3Z4I0 MM

Family and domain databases

CDDicd16024 GPI_EPT_2, 1 hit
Gene3Di3.40.720.10, 1 hit
InterProiView protein in InterPro
IPR017850 Alkaline_phosphatase_core_sf
IPR002591 Phosphodiest/P_Trfase
IPR037674 PIG-G_N
IPR039527 PIGG/GPI7
PANTHERiPTHR23072 PTHR23072, 1 hit
PfamiView protein in Pfam
PF01663 Phosphodiest, 1 hit
SUPFAMiSSF53649 SSF53649, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD3Z4I0_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D3Z4I0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: May 8, 2019
This is version 72 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again