Family with sequence similarity 186, member B

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Coiled coil

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)ⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

        10         20         30         40         50
MEKDNPPHLV TPTSVKAIIS KIETAQLIRT QEDISTQLSD ILDNVNCAIN 
        60         70         80         90        100
RFQEELGYDL KERAKPHQPE QKGKKRFILL EKLAAFSDDA KAKEKHLYEI 
       110        120        130        140        150
LHWLGEWGDS LTYEIKDRSS EEDEALDEWI EVMEKVLPLS LMATKGGIES 
       160        170        180        190        200
LISLCSTLIE DQKKMTQRYK HNFWQDWHEK SPQNKEQGIP VPPSPEQMLQ 
       210        220        230        240        250
DKNTAHLNVS EVRSMLQELL DSTMFNKGEV KAIRYMSAVV ENLNKALTLQ 
       260        270        280        290        300
HKENKSLETK YKYLQVEKNK ELSTQRLHFQ KSIQVLESKR DALLKQVKIL 
       310        320        330        340        350
GDKYHHLLML KHTLEFQLNI AQPASGPEEP TKHFIHYLEP PEKEPLPGQG 
       360        370        380        390        400
TALEKEKQEP KEKGQAVSAL FSSPLTKAWH SGTTPAAPKP IFGTDTDSRV 
       410        420        430        440        450
RDVFVDRTEA LEPVLLHSEV PQIPTQWEKL GDMKDKDQGD HIQEEGAQSK 
       460        470        480        490        500
SLSPGSIRRR LLESHMGHWE EELNWETRRQ QWLQEEEMWL QRQKKWALLE 
       510        520        530        540        550
QEHQEKVRQW EAEAAARQQW QRLTQPEEEK PSPRKEQKAS SEMIFTTTSR 
       560        570        580        590        600
WKSLKKSEST PTPHCRAQSA HQSRSYILAS PHTQQPGQGT QRTLGSAEFL 
       610        620        630        640        650
QRPPTRQVSA KPKKSTSLPV TGTSILRRVS QVSLQQAPGT PKDKVYHIDM 
       660        670        680        690        700
EAQLKNLQVL GGSESEVALP QYLRSKALEV IAIAMDLSIL RLQYLCKKYI 
       710        720        730        740        750
QYRRFQSLRL EMIKHIGAIR QTRVTSKAQN LYLFLENIDH QQSLRLQAWA 
       760        770        780        790        800
DKQRDLEERH QECLHTMVAM FPKLQQEWNV HLSVPVLTHV KPVKSKSSSV 
       810        820        830        840        850
LLQRVRSSHS TTKHRPPPKP RESVPLPITG QQGSQMEAIW KADVASSSHP 
       860        870        880        890        900
IEKKTPTNMC WEQLGGYPDI PRLLVVDEHP SCPRSSVSFK ARSFSASSVQ 
       910        920        930        940 
RKEGQEPSEE LAGPVCKMSS QSLPGSICTK QEGSGSSSTH SIP        

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 100% Identity
• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ