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Protein
Submitted name:

Heterogeneous nuclear ribonucleoprotein H3

Gene

Hnrnph3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Heterogeneous nuclear ribonucleoprotein H3Imported
Submitted name:
MCG11326, isoform CRA_aImported
Gene namesi
Name:Hnrnph3Imported
ORF Names:mCG_11326Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1926462 Hnrnph3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000020069 Expressed in 284 organ(s), highest expression level in ear vesicle

Interactioni

Protein-protein interaction databases

IntActiD3Z3N4, 1 interactor
D3Z3N4, 1 interactor
STRINGi10090.ENSMUSP00000020263

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 93RRMInterPro annotationAdd BLAST78
Domaini195 – 270RRMInterPro annotationAdd BLAST76

Phylogenomic databases

eggNOGiKOG4211 Eukaryota
ENOG410Z6M0 LUCA
GeneTreeiENSGT00760000119102
HOGENOMiHOG000220896
KOiK12898
OMAiVEFRSHE
OrthoDBiEOG091G0CTJ
TreeFamiTF316157

Family and domain databases

CDDicd12732 RRM2_hnRNPH3, 1 hit
cd12735 RRM3_hnRNPH3, 1 hit
Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR034970 hnRNPH3_RRM2
IPR034969 hnRNPH3_RRM3
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 2 hits
SMARTiView protein in SMART
SM00360 RRM, 2 hits
SUPFAMiSSF54928 SSF54928, 2 hits
PROSITEiView protein in PROSITE
PS50102 RRM, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

D3Z3N4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDWVMKHNGP NDASDGTVRL RGLPFGCSKE EIVQFFQGLE IVPNGITLTM
60 70 80 90 100
DYQGRSTGEA FVQFASKEIA ENALGKHKER IGHRYIEIFR SSRSEIKGFY
110 120 130 140 150
DPPRRLLGQR PGPYDRPIGG RGGYYGAGRG SMYDRMRRGG DGYDGGYGGF
160 170 180 190 200
DDYGGYNNYG YGNDGFDDRM RDGRGMGGHG YGGAGDASSG FHGGHFVHMR
210 220 230 240 250
GLPFRATEND IANFFSPLNP IRVHIDIGAD GRATGEADVE FVTHEDAVAA
260 270 280 290 300
MSKDKNNMQH RYIELFLNST PGGGSGMGGS GMGGYGRDGM DNQGGYGSVG
310 320 330 340
RMGMGNSYSG GYGAPDGLGG YGRGGGGSGG YYGQGGMSGG GWRGMY
Length:346
Mass (Da):36,869
Last modified:April 20, 2010 - v1
Checksum:i604F2E5947930E8E
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3YWT1D3YWT1_MOUSE
Heterogeneous nuclear ribonucleopro...
Hnrnph3 mCG_11326
331Annotation score:
D3Z6Y3D3Z6Y3_MOUSE
Heterogeneous nuclear ribonucleopro...
Hnrnph3
71Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113107 Genomic DNA No translation available.
FQ976555 Genomic DNA No translation available.
CH466553 Genomic DNA Translation: EDL32064.1
RefSeqiNP_001073293.1, NM_001079824.1
XP_006513900.1, XM_006513837.3
XP_006513901.1, XM_006513838.3
UniGeneiMm.274784
Mm.336679

Genome annotation databases

EnsembliENSMUST00000020263; ENSMUSP00000020263; ENSMUSG00000020069
GeneIDi432467
KEGGimmu:432467
UCSCiuc007fjo.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113107 Genomic DNA No translation available.
FQ976555 Genomic DNA No translation available.
CH466553 Genomic DNA Translation: EDL32064.1
RefSeqiNP_001073293.1, NM_001079824.1
XP_006513900.1, XM_006513837.3
XP_006513901.1, XM_006513838.3
UniGeneiMm.274784
Mm.336679

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiD3Z3N4, 1 interactor
D3Z3N4, 1 interactor
STRINGi10090.ENSMUSP00000020263

Protocols and materials databases

DNASUi432467
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000020263; ENSMUSP00000020263; ENSMUSG00000020069
GeneIDi432467
KEGGimmu:432467
UCSCiuc007fjo.1 mouse

Organism-specific databases

CTDi3189
MGIiMGI:1926462 Hnrnph3

Phylogenomic databases

eggNOGiKOG4211 Eukaryota
ENOG410Z6M0 LUCA
GeneTreeiENSGT00760000119102
HOGENOMiHOG000220896
KOiK12898
OMAiVEFRSHE
OrthoDBiEOG091G0CTJ
TreeFamiTF316157

Miscellaneous databases

ChiTaRSiHnrnph3 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020069 Expressed in 284 organ(s), highest expression level in ear vesicle

Family and domain databases

CDDicd12732 RRM2_hnRNPH3, 1 hit
cd12735 RRM3_hnRNPH3, 1 hit
Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR034970 hnRNPH3_RRM2
IPR034969 hnRNPH3_RRM3
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 2 hits
SMARTiView protein in SMART
SM00360 RRM, 2 hits
SUPFAMiSSF54928 SSF54928, 2 hits
PROSITEiView protein in PROSITE
PS50102 RRM, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiD3Z3N4_MOUSE
AccessioniPrimary (citable) accession number: D3Z3N4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: November 7, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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