Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Tripartite motif-containing 12C

Gene

Trim12c

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Tripartite motif-containing 12CImported
Gene namesi
Name:Trim12cImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:4821183 Trim12c

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSMUSG00000057143 Expressed in 201 organ(s), highest expression level in blood
GenevisibleiE9Q987 MM

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 59RING-typeInterPro annotationAdd BLAST45
Domaini91 – 132B box-typeInterPro annotationAdd BLAST42
Domaini279 – 497B30.2/SPRYInterPro annotationAdd BLAST219

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili136 – 167Sequence analysisAdd BLAST32
Coiled coili179 – 228Sequence analysisAdd BLAST50

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410ITFH Eukaryota
ENOG410ZW0W LUCA
GeneTreeiENSGT00760000118893
HOGENOMiHOG000234134
KOiK10648
OMAiNYGFLIY
OrthoDBiEOG091G04O8
TreeFamiTF338674

Family and domain databases

CDDicd00021 BBOX, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR001870 B30.2/SPRY
IPR003879 Butyrophylin_SPRY
IPR013320 ConA-like_dom_sf
IPR003877 SPRY_dom
IPR032917 TRIM5
IPR000315 Znf_B-box
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PANTHERiPTHR24103:SF426 PTHR24103:SF426, 1 hit
PfamiView protein in Pfam
PF00622 SPRY, 1 hit
PF00643 zf-B_box, 1 hit
PRINTSiPR01407 BUTYPHLNCDUF
SMARTiView protein in SMART
SM00336 BBOX, 1 hit
SM00184 RING, 1 hit
SM00449 SPRY, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS50188 B302_SPRY, 1 hit
PS50119 ZF_BBOX, 1 hit
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequencei

Sequence statusi: Complete.

D3Z3L3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASQFMKNLK EEVTCPLCLN LMVKPVSADC GHSFCQGCIT VYFESTKCDK
60 70 80 90 100
EMFSCPVCRL SYQSSNLRPN LHVANIVERL KEFKPSPEEE QKVFNCARHG
110 120 130 140 150
EKLQLFCRKD MMAICWLCER SQEHRGHKTA LIEEVAQEYK EQLQVVLQRL
160 170 180 190 200
MADKKEFENW KDDLQKDRTY WENQIQKDVE NVQSEFKRMR DIMNSEEKKE
210 220 230 240 250
LQKLKQEKEN IINKLAESEN EHAQQSKLLE DFISDVEHQL QCSDIEILQG
260 270 280 290 300
VENIIKRSHT FSMKKPKAIA REQRKFRAPD LQGMLQVLQE VTEAQRYWVQ
310 320 330 340 350
VTLVQNNNPN IAITDDKRQI RYEDLQARNL EHGCENSHEG VLGHPVIQSG
360 370 380 390 400
KHYWEVDVSG KGAWVLGLSD GSYLFNPIFR SNAERNPLFR RGIKNDSHYQ
410 420 430 440 450
PKYGFWVIGL WKKSVYNAFE ECPFTGKPSV LTLSLMVPPC RVGVFLDYAA
460 470 480 490
GTLSFYNISN NGTLIYRFCT ASFPDRVFPY FNPMGSSEPM TICWPDS
Length:497
Mass (Da):57,793
Last modified:October 5, 2016 - v2
Checksum:i84ED36E3CBBCEABF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC142110 Genomic DNA No translation available.
RefSeqiNP_001139479.1, NM_001146007.1
NP_783608.3, NM_175677.4
UniGeneiMm.425502

Genome annotation databases

EnsembliENSMUST00000059037; ENSMUSP00000060100; ENSMUSG00000057143
ENSMUST00000130139; ENSMUSP00000116775; ENSMUSG00000057143
GeneIDi319236
KEGGimmu:319236
UCSCiuc009iwb.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC142110 Genomic DNA No translation available.
RefSeqiNP_001139479.1, NM_001146007.1
NP_783608.3, NM_175677.4
UniGeneiMm.425502

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000059037; ENSMUSP00000060100; ENSMUSG00000057143
ENSMUST00000130139; ENSMUSP00000116775; ENSMUSG00000057143
GeneIDi319236
KEGGimmu:319236
UCSCiuc009iwb.2 mouse

Organism-specific databases

CTDi319236
MGIiMGI:4821183 Trim12c

Phylogenomic databases

eggNOGiENOG410ITFH Eukaryota
ENOG410ZW0W LUCA
GeneTreeiENSGT00760000118893
HOGENOMiHOG000234134
KOiK10648
OMAiNYGFLIY
OrthoDBiEOG091G04O8
TreeFamiTF338674

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000057143 Expressed in 201 organ(s), highest expression level in blood
GenevisibleiE9Q987 MM

Family and domain databases

CDDicd00021 BBOX, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR001870 B30.2/SPRY
IPR003879 Butyrophylin_SPRY
IPR013320 ConA-like_dom_sf
IPR003877 SPRY_dom
IPR032917 TRIM5
IPR000315 Znf_B-box
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PANTHERiPTHR24103:SF426 PTHR24103:SF426, 1 hit
PfamiView protein in Pfam
PF00622 SPRY, 1 hit
PF00643 zf-B_box, 1 hit
PRINTSiPR01407 BUTYPHLNCDUF
SMARTiView protein in SMART
SM00336 BBOX, 1 hit
SM00184 RING, 1 hit
SM00449 SPRY, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS50188 B302_SPRY, 1 hit
PS50119 ZF_BBOX, 1 hit
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3Z3L3_MOUSE
AccessioniPrimary (citable) accession number: D3Z3L3
Secondary accession number(s): E9Q987
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: October 5, 2016
Last modified: October 10, 2018
This is version 71 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again