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Protein
Submitted name:

Natural resistance-associated macrophage protein 2

Gene

Slc11a2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Natural resistance-associated macrophage protein 2Imported
Gene namesi
Name:Slc11a2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1345279 Slc11a2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiD3Z0R6
PeptideAtlasiD3Z0R6
PRIDEiD3Z0R6

PTM databases

SwissPalmiD3Z0R6

Expressioni

Gene expression databases

BgeeiENSMUSG00000023030 Expressed in 267 organ(s), highest expression level in cardiac ventricle
ExpressionAtlasiD3Z0R6 baseline and differential

Structurei

3D structure databases

SMRiD3Z0R6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1291 Eukaryota
COG1914 LUCA
GeneTreeiENSGT00390000006526

Family and domain databases

InterProiView protein in InterPro
IPR001046 NRAMP_fam
PANTHERiPTHR11706 PTHR11706, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

D3Z0R6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKKQPRAAA AAPNCELKSY SKSTDPQVST MVLDPKEKMP DDGASGDHGD
60 70 80 90 100
SASLGAINPA YSNSSLPHST GDSEEPFTTY FDEKIPIPEE EYSCFSFRKL
110
WAFTGPGFLM
Length:110
Mass (Da):11,913
Last modified:April 20, 2010 - v1
Checksum:i96C327A729524E9C
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P49282NRAM2_MOUSE
Natural resistance-associated macro...
Slc11a2 Dct1, Dmt1, Nramp2
568Annotation score:
D3Z314D3Z314_MOUSE
Natural resistance-associated macro...
Slc11a2
170Annotation score:
F6ZM31F6ZM31_MOUSE
Natural resistance-associated macro...
Slc11a2
220Annotation score:
D3YXP3D3YXP3_MOUSE
Natural resistance-associated macro...
Slc11a2
50Annotation score:
D6RGP0D6RGP0_MOUSE
Natural resistance-associated macro...
Slc11a2
68Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei110Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139571 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000154331; ENSMUSP00000115357; ENSMUSG00000023030
UCSCiuc007xre.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139571 Genomic DNA No translation available.

3D structure databases

SMRiD3Z0R6
ModBaseiSearch...
MobiDBiSearch...

PTM databases

SwissPalmiD3Z0R6

Proteomic databases

MaxQBiD3Z0R6
PeptideAtlasiD3Z0R6
PRIDEiD3Z0R6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000154331; ENSMUSP00000115357; ENSMUSG00000023030
UCSCiuc007xre.1 mouse

Organism-specific databases

MGIiMGI:1345279 Slc11a2

Phylogenomic databases

eggNOGiKOG1291 Eukaryota
COG1914 LUCA
GeneTreeiENSGT00390000006526

Miscellaneous databases

ChiTaRSiSlc11a2 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000023030 Expressed in 267 organ(s), highest expression level in cardiac ventricle
ExpressionAtlasiD3Z0R6 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR001046 NRAMP_fam
PANTHERiPTHR11706 PTHR11706, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3Z0R6_MOUSE
AccessioniPrimary (citable) accession number: D3Z0R6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: September 12, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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