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Entry version 66 (31 Jul 2019)
Sequence version 1 (20 Apr 2010)
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Protein
Submitted name:

MCG120108, isoform CRA_a

Gene

Rsbn1l

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
MCG120108, isoform CRA_aImported
Submitted name:
Round spermatid basic protein 1-likeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rsbn1lImported
ORF Names:mCG_120108Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3036237 Rsbn1l

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000039968 Expressed in 30 organ(s), highest expression level in thymus

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000039482

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 112DisorderedSequence analysisAdd BLAST112
Regioni128 – 251DisorderedSequence analysisAdd BLAST124
Regioni681 – 762DisorderedSequence analysisAdd BLAST82
Regioni784 – 821DisorderedSequence analysisAdd BLAST38

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi36 – 51PolyampholyteSequence analysisAdd BLAST16
Compositional biasi58 – 72PolarSequence analysisAdd BLAST15
Compositional biasi80 – 112PolarSequence analysisAdd BLAST33
Compositional biasi142 – 229PolyampholyteSequence analysisAdd BLAST88
Compositional biasi230 – 246BasicSequence analysisAdd BLAST17
Compositional biasi684 – 720PolarSequence analysisAdd BLAST37
Compositional biasi789 – 809PolarSequence analysisAdd BLAST21

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4425 Eukaryota
ENOG410XSZP LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001969

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000043117

KEGG Orthology (KO)

More...
KOi
K22610

Database of Orthologous Groups

More...
OrthoDBi
930910at2759

TreeFam database of animal gene trees

More...
TreeFami
TF323256

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026306 RSBN1/Dpy-21

The PANTHER Classification System

More...
PANTHERi
PTHR13354 PTHR13354, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

D3Z0K6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEPPNPARG AVALLSEKEA SGKVQPSSRE PPGSMSAKKV RTEEKKAPRR
60 70 80 90 100
VNGEGGSGGN GGQLQPQSFG SPAAWSFAAR PAASSSSTSR SCYSFSASPS
110 120 130 140 150
VSSASASSSQ PLPRKLLVTP SLLHAQPHRV LLPPVAPPAA AKPRRPKEKR
160 170 180 190 200
EKEKRRQHGL GAAARDENGE AKPLPRDKIK DKIKEKDKER EKKKHKVMSE
210 220 230 240 250
IKKENGDVKI LLKSGKEKPK TNIEDLQIKK VKKKKKKKHK ENEKRKRPKM
260 270 280 290 300
YSKSIQTICS GLLSAEDQEA KSILSDNVKD CIGKNLDTKN CDSKIPDNSD
310 320 330 340 350
FPFVSLKEPR DKNNLRRLDT LAFRQLIHIE HQPNGGAAVI HAYSNELSCL
360 370 380 390 400
SPMEMQRFAE EFVGLVFSEN ESSAAFYVMG IVHGAATYLP DFLDYFSYNF
410 420 430 440 450
PNSPVKMEIL GKKDIETTTM SNFHAQVKRT YSHGTYRAGP MRQISLVGAV
460 470 480 490 500
DEEVGDYFPE FLDMLEASPF LKCTLPWGTL SSLKLESRKD SDDGPIMWVR
510 520 530 540 550
PGEQMIPVAD MPKSPFKRKR TTNEIKNLQY LPRTSEPREM LFEDRTRAHA
560 570 580 590 600
DHIGQGFERQ TTAAVGVLKA VHCGQRPDQP RVTKDVICFH AEDFLEVVQR
610 620 630 640 650
MQLDLHEPPL SQCVQWVDDA KLNQLRREGI RYARIQLYDN DIYFIPRNVV
660 670 680 690 700
HQFKTVSAVC SLAWHVRLKF YHAEEDTCHS TSESTHEKGI ASGPTSSVLG
710 720 730 740 750
AHTENQASSD SVLSDKLPSK YESQQIKHEP GAALRIKEEP GMAPIPEKIR
760 770 780 790 800
TPNNTEGKNS KARLDRAQFS DFHIDMDSAF ENTNKDLKED SCPGSVSNTV
810 820
DTQQHSSVRS SQDRSEDDSL C
Length:821
Mass (Da):91,746
Last modified:April 20, 2010 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4F092FF2187B4ACD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JEI9A0A0G2JEI9_MOUSE
Round spermatid basic protein 1-lik...
Rsbn1l
616Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JDQ6A0A0G2JDQ6_MOUSE
Round spermatid basic protein 1-lik...
Rsbn1l
71Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AC116501 Genomic DNA No translation available.
AC125024 Genomic DNA No translation available.
CH466586 Genomic DNA Translation: EDL03217.1

NCBI Reference Sequences

More...
RefSeqi
NP_001074446.1, NM_001080977.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000036489; ENSMUSP00000039482; ENSMUSG00000039968

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
242860

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:242860

UCSC genome browser

More...
UCSCi
uc008wod.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC116501 Genomic DNA No translation available.
AC125024 Genomic DNA No translation available.
CH466586 Genomic DNA Translation: EDL03217.1
RefSeqiNP_001074446.1, NM_001080977.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000039482

Genome annotation databases

EnsembliENSMUST00000036489; ENSMUSP00000039482; ENSMUSG00000039968
GeneIDi242860
KEGGimmu:242860
UCSCiuc008wod.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
222194
MGIiMGI:3036237 Rsbn1l

Phylogenomic databases

eggNOGiKOG4425 Eukaryota
ENOG410XSZP LUCA
GeneTreeiENSGT00390000001969
HOGENOMiHOG000043117
KOiK22610
OrthoDBi930910at2759
TreeFamiTF323256

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Rsbn1l mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000039968 Expressed in 30 organ(s), highest expression level in thymus

Family and domain databases

InterProiView protein in InterPro
IPR026306 RSBN1/Dpy-21
PANTHERiPTHR13354 PTHR13354, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiD3Z0K6_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: D3Z0K6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: July 31, 2019
This is version 66 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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