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Protein
Submitted name:

Splicing factor 1

Gene

Sf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Splicing factor 1Imported
Gene namesi
Name:Sf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:1095403 Sf1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiD3YZD0
PeptideAtlasiD3YZD0
PRIDEiD3YZD0

Expressioni

Gene expression databases

BgeeiENSMUSG00000024949 Expressed in 288 organ(s), highest expression level in ear
ExpressionAtlasiD3YZD0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliD3YZD0
SMRiD3YZD0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini279 – 293CCHC-typeInterPro annotationAdd BLAST15

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0119 Eukaryota
COG5176 LUCA
GeneTreeiENSGT00550000074434
HOGENOMiHOG000237321

Family and domain databases

Gene3Di3.30.1370.10, 1 hit
InterProiView protein in InterPro
IPR031150 BBP/SF1
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR032570 SF1-HH
IPR001878 Znf_CCHC
PANTHERiPTHR11208:SF45 PTHR11208:SF45, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF16275 SF1-HH, 1 hit
PF00098 zf-CCHC, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00343 ZnF_C2HC, 1 hit
SUPFAMiSSF54791 SSF54791, 1 hit
PROSITEiView protein in PROSITE
PS50158 ZF_CCHC, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

D3YZD0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATGANATPL DFPSKKRKRS RWNQDTMEQK TVIPGMPTVI PPGLTREQER
60 70 80 90 100
AYIVQLQIED LTRKLRTGDL GIPPNPEDRS PSPEPIYNSE GKRLNTREFR
110 120 130 140 150
TRKKLEEERH TLITEMVALN PDFKPPADYK PPATRVSDKV MIPQDEYPEI
160 170 180 190 200
NFVGLLIGPR GNTLKNIEKE CNAKIMIRGK GSVKEGKVGR KDGQMLPGED
210 220 230 240 250
EPLHALVTAN TMENVKKAVE QIRNILKQGI ETPEDQNDLR KMQLRELARL
260 270 280 290 300
NGTLREDDNR ILRPWQSSET RSITNTTVCT KCGGAGHIAS DCKFQRPGDP
310 320 330 340 350
QSAQDKARMD KEYLSLMAEL GEAPVPASVG STSGPATTPL ASAPRPAAPA
360 370 380 390 400
SNPPPPSLMS TTQSRPPWMN SGPSENRPYH GMHGGGPGGP GGGPHSFPHP
410 420 430 440 450
LPSLTGGHGG HPMQHNPNGP PPPWMQPPPP PMNQGPHPPG HHGPPPMDQY
460 470 480 490 500
LGSTPVGSGV YRLHQGKGMM PPPPMGMMPP PPPPPSGQPP PPPSGPLPPW
510 520 530 540 550
QQQQQQPPPP PPPSSSMASS TPLPWQQNTT TTTTSAGTGS IPPWQQQQAA
560 570 580 590 600
AAASPGTPQM QGNPTMVPLP PGVQPPLPPG APPPPPPPPP GSAGMMIPPR
610 620 630
GSDGPSHESE DFPRPLVTLP GRQPQQRPWW TGWFGKAA
Length:638
Mass (Da):68,680
Last modified:April 20, 2010 - v1
Checksum:iB2387D7EEDFD2D91
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q64213SF01_MOUSE
Splicing factor 1
Sf1 Zfm1, Zfp162
653Annotation score:
D3YZC9D3YZC9_MOUSE
Splicing factor 1
Sf1
571Annotation score:
E9Q4Q2E9Q4Q2_MOUSE
Splicing factor 1
Sf1
548Annotation score:
D3YVH4D3YVH4_MOUSE
Splicing factor 1
Sf1
267Annotation score:
F6YR19F6YR19_MOUSE
Splicing factor 1
Sf1
225Annotation score:
D6RDB7D6RDB7_MOUSE
Splicing factor 1
Sf1
84Annotation score:
F8WHF9F8WHF9_MOUSE
Splicing factor 1
Sf1
110Annotation score:
F6Z9W2F6Z9W2_MOUSE
Splicing factor 1
Sf1
200Annotation score:
F6SRV1F6SRV1_MOUSE
Splicing factor 1
Sf1
171Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC127556 Genomic DNA No translation available.
AC167245 Genomic DNA No translation available.
RefSeqiXP_006531803.1, XM_006531740.3
UniGeneiMm.256422
Mm.453047

Genome annotation databases

EnsembliENSMUST00000113488; ENSMUSP00000109116; ENSMUSG00000024949
GeneIDi22668

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC127556 Genomic DNA No translation available.
AC167245 Genomic DNA No translation available.
RefSeqiXP_006531803.1, XM_006531740.3
UniGeneiMm.256422
Mm.453047

3D structure databases

ProteinModelPortaliD3YZD0
SMRiD3YZD0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiD3YZD0
PeptideAtlasiD3YZD0
PRIDEiD3YZD0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000113488; ENSMUSP00000109116; ENSMUSG00000024949
GeneIDi22668

Organism-specific databases

CTDi7536
MGIiMGI:1095403 Sf1

Phylogenomic databases

eggNOGiKOG0119 Eukaryota
COG5176 LUCA
GeneTreeiENSGT00550000074434
HOGENOMiHOG000237321

Miscellaneous databases

ChiTaRSiSf1 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000024949 Expressed in 288 organ(s), highest expression level in ear
ExpressionAtlasiD3YZD0 baseline and differential

Family and domain databases

Gene3Di3.30.1370.10, 1 hit
InterProiView protein in InterPro
IPR031150 BBP/SF1
IPR004087 KH_dom
IPR004088 KH_dom_type_1
IPR036612 KH_dom_type_1_sf
IPR032570 SF1-HH
IPR001878 Znf_CCHC
PANTHERiPTHR11208:SF45 PTHR11208:SF45, 1 hit
PfamiView protein in Pfam
PF00013 KH_1, 1 hit
PF16275 SF1-HH, 1 hit
PF00098 zf-CCHC, 1 hit
SMARTiView protein in SMART
SM00322 KH, 1 hit
SM00343 ZnF_C2HC, 1 hit
SUPFAMiSSF54791 SSF54791, 1 hit
PROSITEiView protein in PROSITE
PS50158 ZF_CCHC, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3YZD0_MOUSE
AccessioniPrimary (citable) accession number: D3YZD0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: September 12, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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