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UniProtKB - D3YYM0 (OVOL3_MOUSE)
Protein
Putative transcription factor ovo-like protein 3
Gene
Ovol3
Organism
Mus musculus (Mouse)
Status
Functioni
May act as a transcription regulator.
By similarityRegions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 69 – 91 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 97 – 119 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 125 – 148 | C2H2-type 3PROSITE-ProRule annotationAdd BLAST | 24 |
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- metal ion binding Source: UniProtKB-KW
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- epidermal cell differentiation Source: GO_Central
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Putative transcription factor ovo-like protein 3 |
Gene namesi | Name:Ovol3 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2388075, Ovol3 |
VEuPathDBi | HostDB:ENSMUSG00000100512 |
Subcellular locationi
Nucleus
- Nucleus Curated
Nucleus
- nucleus Source: GO_Central
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000415414 | 1 – 189 | Putative transcription factor ovo-like protein 3Add BLAST | 189 |
Proteomic databases
PRIDEi | D3YYM0 |
PTM databases
PhosphoSitePlusi | D3YYM0 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000100512, Expressed in liver and 46 other tissues |
Interactioni
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000140811 |
Miscellaneous databases
RNActi | D3YYM0, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 20 | DisorderedSequence analysisAdd BLAST | 20 |
Sequence similaritiesi
Belongs to the krueppel C2H2-type zinc-finger protein family.Curated
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 69 – 91 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 97 – 119 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 125 – 148 | C2H2-type 3PROSITE-ProRule annotationAdd BLAST | 24 |
Keywords - Domaini
Repeat, Zinc-fingerPhylogenomic databases
eggNOGi | KOG3576, Eukaryota |
GeneTreei | ENSGT00940000162348 |
HOGENOMi | CLU_087964_0_0_1 |
InParanoidi | D3YYM0 |
OMAi | RRHVCRC |
OrthoDBi | 1419156at2759 |
PhylomeDBi | D3YYM0 |
Family and domain databases
InterProi | View protein in InterPro IPR027756, Ovo-like IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR10032, PTHR10032, 1 hit |
Pfami | View protein in Pfam PF00096, zf-C2H2, 3 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 4 hits |
SUPFAMi | SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
i Sequence
Sequence statusi: Complete.
D3YYM0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPRVFLVRSR RPQPPNWSHL PDQLRGDAYV PDCSSLAVPP AHRSSGLRDT
60 70 80 90 100
WAVSSQGTLT SAPKGPGTLG CPLCPKAFPL QRMLTRHLKC HSPARRHVCH
110 120 130 140 150
YCGKGFHDAF DLKRHMRTHT GIRPFRCGAC GKAFTQRCSL EAHLAKVHGQ
160 170 180
PASYAYRERR EKLHVCEDCG FTSSRPDAYA QHRTLHRTT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC149067 Genomic DNA No translation available. |
CCDSi | CCDS80691.1 |
RefSeqi | NP_001276746.1, NM_001289817.1 XP_011248918.1, XM_011250616.2 |
Genome annotation databases
Ensembli | ENSMUST00000189482; ENSMUSP00000140811; ENSMUSG00000100512 |
GeneIDi | 381867 |
KEGGi | mmu:381867 |
UCSCi | uc033iyh.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC149067 Genomic DNA No translation available. |
CCDSi | CCDS80691.1 |
RefSeqi | NP_001276746.1, NM_001289817.1 XP_011248918.1, XM_011250616.2 |
3D structure databases
SMRi | D3YYM0 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000140811 |
PTM databases
PhosphoSitePlusi | D3YYM0 |
Proteomic databases
PRIDEi | D3YYM0 |
Genome annotation databases
Ensembli | ENSMUST00000189482; ENSMUSP00000140811; ENSMUSG00000100512 |
GeneIDi | 381867 |
KEGGi | mmu:381867 |
UCSCi | uc033iyh.1, mouse |
Organism-specific databases
CTDi | 728361 |
MGIi | MGI:2388075, Ovol3 |
VEuPathDBi | HostDB:ENSMUSG00000100512 |
Phylogenomic databases
eggNOGi | KOG3576, Eukaryota |
GeneTreei | ENSGT00940000162348 |
HOGENOMi | CLU_087964_0_0_1 |
InParanoidi | D3YYM0 |
OMAi | RRHVCRC |
OrthoDBi | 1419156at2759 |
PhylomeDBi | D3YYM0 |
Miscellaneous databases
BioGRID-ORCSi | 381867, 0 hits in 38 CRISPR screens |
PROi | PR:D3YYM0 |
RNActi | D3YYM0, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000100512, Expressed in liver and 46 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR027756, Ovo-like IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR10032, PTHR10032, 1 hit |
Pfami | View protein in Pfam PF00096, zf-C2H2, 3 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 4 hits |
SUPFAMi | SSF57667, SSF57667, 1 hit |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | OVOL3_MOUSE | |
Accessioni | D3YYM0Primary (citable) accession number: D3YYM0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 25, 2012 |
Last sequence update: | April 16, 2014 | |
Last modified: | February 23, 2022 | |
This is version 76 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families