UniProtKB - D3YX59 (D3YX59_MOUSE)
Protein
Submitted name:
Nicotinamide N-methyltransferase
Gene
Nnmt
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- methyltransferase activity Source: UniProtKB-KW
GO - Biological processi
- methylation Source: UniProtKB-KW
Keywordsi
Molecular function | MethyltransferaseARBA annotation, Transferase |
Names & Taxonomyi
Protein namesi | Submitted name: Nicotinamide N-methyltransferaseImported |
Gene namesi | Name:NnmtImported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1099443, Nnmt |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000032271, Expressed in white adipose tissue and 173 other tissues |
ExpressionAtlasi | D3YX59, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 123 – 157 | DisorderedSequence analysisAdd BLAST | 35 |
Sequence similaritiesi
Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT00390000011708 |
HOGENOMi | CLU_141713_1_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR025820, NNMT/PNMT/TEMT_CS IPR000940, NNMT_TEMT_trans IPR029063, SAM-dependent_MTases |
PANTHERi | PTHR10867, PTHR10867, 1 hit |
Pfami | View protein in Pfam PF01234, NNMT_PNMT_TEMT, 1 hit |
SUPFAMi | SSF53335, SSF53335, 1 hit |
PROSITEi | View protein in PROSITE PS01100, NNMT_PNMT_TEMT, 1 hit PS51681, SAM_MT_NNMT_PNMT_TEMT, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
D3YX59-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MESGFTSKDT YLSHFNPRDY LEKYYSFGSR HCAENEILRH LLKNLFKIFC
60 70 80 90 100
LGAVKGELLI DIGSGPTIYQ LLSACESFTE IIVSDYTDQN LWELQKWLKK
110 120 130 140 150
EPGAFDWSPV VTYVCDLEGN RMKGPEKEEK LRRAIKQEPG QSAQARRLPG
DGRCPEE
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketO55239 | NNMT_MOUSE | Nicotinamide N-methyltransferase | Nnmt | 264 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC113548 Genomic DNA No translation available. |
RefSeqi | NP_001297991.1, NM_001311062.1 |
Genome annotation databases
Ensembli | ENSMUST00000119426; ENSMUSP00000112381; ENSMUSG00000032271 |
GeneIDi | 18113 |
UCSCi | uc009pij.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC113548 Genomic DNA No translation available. |
RefSeqi | NP_001297991.1, NM_001311062.1 |
3D structure databases
SMRi | D3YX59 |
ModBasei | Search... |
Proteomic databases
jPOSTi | D3YX59 |
MaxQBi | D3YX59 |
PeptideAtlasi | D3YX59 |
PRIDEi | D3YX59 |
Protocols and materials databases
Antibodypediai | 18379, 462 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000119426; ENSMUSP00000112381; ENSMUSG00000032271 |
GeneIDi | 18113 |
UCSCi | uc009pij.1, mouse |
Organism-specific databases
CTDi | 4837 |
MGIi | MGI:1099443, Nnmt |
Phylogenomic databases
GeneTreei | ENSGT00390000011708 |
HOGENOMi | CLU_141713_1_0_1 |
Miscellaneous databases
BioGRID-ORCSi | 18113, 0 hits in 17 CRISPR screens |
ChiTaRSi | Nnmt, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000032271, Expressed in white adipose tissue and 173 other tissues |
ExpressionAtlasi | D3YX59, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR025820, NNMT/PNMT/TEMT_CS IPR000940, NNMT_TEMT_trans IPR029063, SAM-dependent_MTases |
PANTHERi | PTHR10867, PTHR10867, 1 hit |
Pfami | View protein in Pfam PF01234, NNMT_PNMT_TEMT, 1 hit |
SUPFAMi | SSF53335, SSF53335, 1 hit |
PROSITEi | View protein in PROSITE PS01100, NNMT_PNMT_TEMT, 1 hit PS51681, SAM_MT_NNMT_PNMT_TEMT, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D3YX59_MOUSE | |
Accessioni | D3YX59Primary (citable) accession number: D3YX59 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | April 20, 2010 | |
Last modified: | December 2, 2020 | |
This is version 61 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |