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Protein
Submitted name:

Spectrin beta, non-erythrocytic 4

Gene

Sptbn4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • actin binding Source: MGI
  • ankyrin binding Source: MGI
  • phosphatase binding Source: MGI
  • spectrin binding Source: MGI

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-375165 NCAM signaling for neurite out-growth
R-MMU-445095 Interaction between L1 and Ankyrins
R-MMU-5673001 RAF/MAP kinase cascade
R-MMU-6807878 COPI-mediated anterograde transport

Names & Taxonomyi

Protein namesi
Submitted name:
Spectrin beta, non-erythrocytic 4Imported
Gene namesi
Name:Sptbn4Imported
Synonyms:Spnb4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1890574 Sptbn4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiD3YWH8
PeptideAtlasiD3YWH8
PRIDEiD3YWH8

Expressioni

Gene expression databases

BgeeiENSMUSG00000011751 Expressed in 99 organ(s), highest expression level in cerebellum
ExpressionAtlasiD3YWH8 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiD3YWH8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini81 – 128Calponin-homology (CH)InterPro annotationAdd BLAST48

Phylogenomic databases

eggNOGiKOG0035 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00760000118813

Family and domain databases

Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
PfamiView protein in Pfam
PF00307 CH, 1 hit
SUPFAMiSSF47576 SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS50021 CH, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

D3YWH8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVVGDTRFHS LCCNALPPPM AQVPGEVDNM EGPAVSNNNN PSARWESPDR
60 70 80 90 100
GWDREPPAAA NAAASLFECS RIKALADERE AVQKKTFTKW VNSHLARVGC
110 120
HIGDLYADLR DGFVLTRLLE VLSGEQLV
Length:128
Mass (Da):14,017
Last modified:April 20, 2010 - v1
Checksum:i6AD38AEDB3030938
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q91ZE6Q91ZE6_MOUSE
Spectrin beta chain
Sptbn4 Spnb4
2,555Annotation score:
E9PX29E9PX29_MOUSE
Spectrin beta chain
Sptbn4 Spnb4
2,561Annotation score:
E9PZC2E9PZC2_MOUSE
Spectrin beta, non-erythrocytic 4
Sptbn4 Spnb4
1,241Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei128Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC157561 Genomic DNA No translation available.
AC158304 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000152572; ENSMUSP00000120738; ENSMUSG00000011751

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC157561 Genomic DNA No translation available.
AC158304 Genomic DNA No translation available.

3D structure databases

SMRiD3YWH8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiD3YWH8
PeptideAtlasiD3YWH8
PRIDEiD3YWH8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000152572; ENSMUSP00000120738; ENSMUSG00000011751

Organism-specific databases

MGIiMGI:1890574 Sptbn4

Phylogenomic databases

eggNOGiKOG0035 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00760000118813

Enzyme and pathway databases

ReactomeiR-MMU-375165 NCAM signaling for neurite out-growth
R-MMU-445095 Interaction between L1 and Ankyrins
R-MMU-5673001 RAF/MAP kinase cascade
R-MMU-6807878 COPI-mediated anterograde transport

Miscellaneous databases

ChiTaRSiSptbn4 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000011751 Expressed in 99 organ(s), highest expression level in cerebellum
ExpressionAtlasiD3YWH8 baseline and differential

Family and domain databases

Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
PfamiView protein in Pfam
PF00307 CH, 1 hit
SUPFAMiSSF47576 SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS50021 CH, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiD3YWH8_MOUSE
AccessioniPrimary (citable) accession number: D3YWH8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 20, 2010
Last sequence update: April 20, 2010
Last modified: September 12, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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