UniProtKB - D3YVV7 (D3YVV7_MOUSE)
Protein
Submitted name:
NOVA alternative-splicing regulator 2
Gene
Nova2
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- mRNA binding Source: GO_Central
- RNA binding Source: MGI
GO - Biological processi
- mRNA splicing, via spliceosome Source: GO_Central
- negative regulation of cold-induced thermogenesis Source: YuBioLab
- regulation of alternative mRNA splicing, via spliceosome Source: GO_Central
- regulation of gene expression Source: GO_Central
- regulation of RNA metabolic process Source: MGI
Names & Taxonomyi
Protein namesi | Submitted name: NOVA alternative-splicing regulator 2Imported |
Gene namesi | Name:Nova2Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:104296, Nova2 |
Subcellular locationi
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
ChainiPRO_5006722359 | 20 – 556 | Sequence analysisAdd BLAST | 537 |
Proteomic databases
MaxQBi | D3YVV7 |
PeptideAtlasi | D3YVV7 |
PRIDEi | D3YVV7 |
PTM databases
PhosphoSitePlusi | D3YVV7 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000030411, Expressed in primary visual cortex and 146 other tissues |
Interactioni
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000134257 |
Miscellaneous databases
RNActi | D3YVV7, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 95 – 168 | KHInterPro annotationAdd BLAST | 74 | |
Domaini | 193 – 265 | KHInterPro annotationAdd BLAST | 73 | |
Domaini | 469 – 542 | KHInterPro annotationAdd BLAST | 74 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 88 | DisorderedSequence analysisAdd BLAST | 88 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 17 – 67 | Pro-richSequence analysisAdd BLAST | 51 |
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
eggNOGi | KOG2191, Eukaryota |
GeneTreei | ENSGT00940000161740 |
HOGENOMi | CLU_022670_1_1_1 |
OMAi | HRALHMI |
Family and domain databases
Gene3Di | 3.30.1370.10, 3 hits |
InterProi | View protein in InterPro IPR004087, KH_dom IPR004088, KH_dom_type_1 IPR036612, KH_dom_type_1_sf IPR033087, Nova-2 |
PANTHERi | PTHR10288:SF162, PTHR10288:SF162, 1 hit |
Pfami | View protein in Pfam PF00013, KH_1, 3 hits |
SMARTi | View protein in SMART SM00322, KH, 3 hits |
SUPFAMi | SSF54791, SSF54791, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
D3YVV7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRMMAAGAVH GLFTASAAPQ PPPPPPPPPP PQPQPPQQPS PPPQQPPPPP
60 70 80 90 100
QPPQQQQPPP QAPPMEPEAP DSRKRPLETP PEVVCTKRSN TGEEGEYFLK
110 120 130 140 150
VLIPSYAAGS IIGKGGQTIV QLQKETGATI KLSKSKDFYP GTTERVCLVQ
160 170 180 190 200
GTAEALNAVH SFIAEKVREI PQAMTKPEVV NILQPQTTMN PDRAKQAKLI
210 220 230 240 250
VPNSTAGLII GKGGATVKAV MEQSGAWVQL SQKPEGINLQ ERVVTVSGEP
260 270 280 290 300
EQVHKAVSAI VQKVQEDPQS SSCLNISYAN VAGPVANSNP TGSPYASPAD
310 320 330 340 350
VLPAAAAASA AAASGLLGPA GLAGVGAFPA ALPAFSGTDL LAISTALNTL
360 370 380 390 400
ASYGYNTNSL SLGLNSAAAS GVLAAVAAGA NPAAAAAANL LASYAGDAGA
410 420 430 440 450
GPGAGAAPPP PPPPGALGSF ALAAAANGYL GAGAGGAAGA GGAPLVAAAA
460 470 480 490 500
AAGAAGGFLT AEKLAAESAK ELVEIAVPEN LVGAILGKGG KTLVEYQELT
510 520 530 540 550
GARIQISKKG EFLPGTRNRR VTITGSPAAT QAAQYLISQR VTYEQGVRAS
NPQKVG
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1W2P872 | A0A1W2P872_MOUSE | NOVA alternative-splicing regulator... | Nova2 | 492 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC153651 Genomic DNA No translation available. AC170864 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSMUST00000032571; ENSMUSP00000032571; ENSMUSG00000030411 |
UCSCi | uc012fau.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC153651 Genomic DNA No translation available. AC170864 Genomic DNA No translation available. |
3D structure databases
SMRi | D3YVV7 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000134257 |
PTM databases
PhosphoSitePlusi | D3YVV7 |
Proteomic databases
MaxQBi | D3YVV7 |
PeptideAtlasi | D3YVV7 |
PRIDEi | D3YVV7 |
Protocols and materials databases
Antibodypediai | 18063, 158 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000032571; ENSMUSP00000032571; ENSMUSG00000030411 |
UCSCi | uc012fau.1, mouse |
Organism-specific databases
MGIi | MGI:104296, Nova2 |
Phylogenomic databases
eggNOGi | KOG2191, Eukaryota |
GeneTreei | ENSGT00940000161740 |
HOGENOMi | CLU_022670_1_1_1 |
OMAi | HRALHMI |
Miscellaneous databases
ChiTaRSi | Nova2, mouse |
RNActi | D3YVV7, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000030411, Expressed in primary visual cortex and 146 other tissues |
Family and domain databases
Gene3Di | 3.30.1370.10, 3 hits |
InterProi | View protein in InterPro IPR004087, KH_dom IPR004088, KH_dom_type_1 IPR036612, KH_dom_type_1_sf IPR033087, Nova-2 |
PANTHERi | PTHR10288:SF162, PTHR10288:SF162, 1 hit |
Pfami | View protein in Pfam PF00013, KH_1, 3 hits |
SMARTi | View protein in SMART SM00322, KH, 3 hits |
SUPFAMi | SSF54791, SSF54791, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | D3YVV7_MOUSE | |
Accessioni | D3YVV7Primary (citable) accession number: D3YVV7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 20, 2010 |
Last sequence update: | February 17, 2016 | |
Last modified: | August 12, 2020 | |
This is version 83 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |